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Ziyang Pan

Publications and source records attributed to Ziyang Pan.

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Multi-Signal Safety Surveillance with Bayesian Latent Factor Modeling and Bias Correction

Safety surveillance increasingly involves repeated monitoring of many exposure-outcome signals in observational healthcare data, where sparse information, dependence across related signals, and systematic error can complicate inference. Existing frameworks typically focus on either correcting residual bias using negative controls or borrowing information across exposure-outcome pairs, but not both. We propose a multi-signal Bayesian sequential surveillance framework that integrates empirical bias correction with low-rank latent factor modeling. At each analysis time, a hierarchical Bayesian model learns exposure-specific bias distributions from negative control outcomes assumed to have null latent effects. Conditional on these distributions, low-rank latent factors are estimated across exposures and outcomes of interest to share information across correlated signals. As new data accrue, posterior inference is updated sequentially, yielding bias-corrected posterior summaries of effect sizes across multiple monitored signals. We illustrate the method in a postmarket vaccine safety surveillance study using a large US insurance claims database.

stat.ME

GLM-5V-Turbo: Toward a Native Foundation Model for Multimodal Agents

We present GLM-5V-Turbo, a step toward native foundation models for multimodal agents. As foundation models are increasingly deployed in real environments, agentic capability depends not only on language reasoning, but also on the ability to perceive, interpret, and act over heterogeneous contexts such as images, videos, webpages, documents, GUIs. GLM-5V-Turbo is built around this objective: multimodal perception is integrated as a core component of reasoning, planning, tool use, and execution, rather than as an auxiliary interface to a language model. This report summarizes the main improvements behind GLM-5V-Turbo across model design, multimodal training, reinforcement learning, toolchain expansion, and integration with agent frameworks. These developments lead to strong performance in multimodal coding, visual tool use, and framework-based agentic tasks, while preserving competitive text-only coding capability. More importantly, our development process offers practical insights for building multimodal agents, highlighting the central role of multimodal perception, hierarchical optimization, and reliable end-to-end verification.

cs.CV

Vision2Web: A Hierarchical Benchmark for Visual Website Development with Agent Verification

Recent advances in large language models have improved the capabilities of coding agents, yet systematic evaluation of complex, end-to-end website development remains limited. To address this gap, we introduce Vision2Web, a hierarchical benchmark for visual website development, spanning from static UI-to-code generation, interactive multi-page frontend reproduction, to long-horizon full-stack website development. The benchmark is constructed from real-world websites and comprises a total of 193 tasks across 16 categories, with 918 prototype images and 1,255 test cases. To support flexible, thorough and reliable evaluation, we propose workflow-based agent verification paradigm based on two complementary components: a GUI agent verifier and a VLM-based judge. We evaluate multiple visual language models instantiated under different coding-agent frameworks, revealing substantial performance gaps at all task levels, with state-of-the-art models still struggling on full-stack development.

cs.SE

GLM-4.5V and GLM-4.1V-Thinking: Towards Versatile Multimodal Reasoning with Scalable Reinforcement Learning

We present GLM-4.1V-Thinking, GLM-4.5V, and GLM-4.6V, a family of vision-language models (VLMs) designed to advance general-purpose multimodal understanding and reasoning. In this report, we share our key findings in the development of the reasoning-centric training framework. We first develop a capable vision foundation model with significant potential through large-scale pre-training, which arguably sets the upper bound for the final performance. We then propose Reinforcement Learning with Curriculum Sampling (RLCS) to unlock the full potential of the model, leading to comprehensive capability enhancement across a diverse range of tasks, including STEM problem solving, video understanding, content recognition, coding, grounding, GUI-based agents, and long document interpretation. In a comprehensive evaluation across 42 public benchmarks, GLM-4.5V achieves state-of-the-art performance on nearly all tasks among open-source models of similar size, and demonstrates competitive or even superior results compared to closed-source models such as Gemini-2.5-Flash on challenging tasks including Coding and GUI Agents. Meanwhile, the smaller GLM-4.1V-9B-Thinking remains highly competitive-achieving superior results to the much larger Qwen2.5-VL-72B on 29 benchmarks. We open-source both GLM-4.1V-9B-Thinking and GLM-4.5V. We further introduce the GLM-4.6V series, open-source multimodal models with native tool use and a 128K context window. A brief overview is available at https://z.ai/blog/glm-4.6v. Code, models and more information are released at https://github.com/zai-org/GLM-V.

cs.CV

Data Integration in Causal Inference

Integrating data from multiple heterogeneous sources has become increasingly popular to achieve a large sample size and diverse study population. This paper reviews development in causal inference methods that combines multiple datasets collected by potentially different designs from potentially heterogeneous populations. We summarize recent advances on combining randomized clinical trial with external information from observational studies or historical controls, combining samples when no single sample has all relevant variables with application to two-sample Mendelian randomization, distributed data setting under privacy concerns for comparative effectiveness and safety research using real-world data, Bayesian causal inference, and causal discovery methods.

stat.ME