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Zongliang Yue

Publications and source records attributed to Zongliang Yue.

5 recordsLinked to original sources

A Temporal Machine Learning-Based Time-to-Event Model for Predicting ALS Progression and Healthcare Utilization

Amyotrophic lateral sclerosis (ALS) is a progressive and heterogeneous neurodegenerative disease in which predicting clinically meaningful milestones, such as assistive device use, remains challenging. We developed a time-to-event, digital-twin-inspired framework that integrates longitudinal ALS Functional Rating Scale-Revised (ALSFRS-R) trajectories with survival modeling to support individualized prediction of functional decline and assistive device utilization. We constructed a harmonized longitudinal dataset by integrating diagnosis records, ALSFRS-R assessments, activities of daily living, and demographic information, followed by preprocessing to ensure data quality, temporal alignment, and cohort consistency. Correlation-based clustering identified coherent functional domains spanning bulbar, upper limb, axial, lower limb, and respiratory systems. Generalized additive mixed models characterized nonlinear, domain-specific functional decline across all domains. In addition, a temporal machine learning model was developed to predict longitudinal functional decline and capture stage-dependent disease progression. Cox proportional hazards modeling further identified lower limb function, particularly walking and stair climbing, as the strongest predictors of earlier wheelchair access. Building on these results, we implemented a digital twin-inspired temporal machine learning-based time-to-event (TTE) model that generates individualized survival curves and dynamically predicts wheelchair-free survival. This framework provides a scalable, interpretable, and clinically actionable approach for linking ALS progression with personalized decision support, with applications in proactive care planning, clinical trial stratification, and precision medicine.

cs.LG

Optimizing Carbon Footprint in ICT through Swarm Intelligence with Algorithmic Complexity

Global emissions from fossil fuel combustion and cement production were recorded in 2022, signaling a resurgence to pre-pandemic levels and providing an apodictic indication that emission peaks have not yet been achieved. Significant contributions to this upward trend are made by the Information and Communication Technology (ICT) industry due to its substantial energy consumption. This shows the need for further exploration of swarm intelligence applications to measure and optimize the carbon footprint within ICT. All causative factors are evaluated based on the quality of data collection; variations from each source are quantified; and an objective function related to carbon footprint in ICT energy management is optimized. Emphasis is placed on the asyndetic integration of data sources to construct a convex optimization problem. An apodictic necessity to prevent the erosion of accuracy in carbon footprint assessments is addressed. Complexity percentages ranged from 5.25% for the Bat Algorithm to 7.87% for Fast Bacterial Swarming, indicating significant fluctuations in resource intensity among algorithms. These findings suggest that we were able to quantify the environmental impact of various swarm algorithms.

cs.NE

Handwriting Anomalies and Learning Disabilities through Recurrent Neural Networks and Geometric Pattern Analysis

Dyslexia and dysgraphia are learning disabilities that profoundly impact reading, writing, and language processing capabilities. Dyslexia primarily affects reading, manifesting as difficulties in word recognition and phonological processing, where individuals struggle to connect sounds with their corresponding letters. Dysgraphia, on the other hand, affects writing skills, resulting in difficulties with letter formation, spacing, and alignment. The coexistence of dyslexia and dysgraphia complicates diagnosis, requiring a nuanced approach capable of adapting to these complexities while accurately identifying and differentiating between the disorders. This study utilizes advanced geometrical patterns and recurrent neural networks (RNN) to identify handwriting anomalies indicative of dyslexia and dysgraphia. Handwriting is first standardized, followed by feature extraction that focuses on baseline deviations, letter connectivity, stroke thickness, and other anomalies. These features are then fed into an RNN-based autoencoder to identify irregularities. Initial results demonstrate the ability of this RNN model to achieve state-of-art performance on combined dyslexia and dysgraphia detection, while showing the challenges associated with complex pattern adaptation of deep-learning to a diverse corpus of about 33,000 writing samples.

q-bio.QM

Integrating Artificial Open Generative Artificial Intelligence into Software Supply Chain Security

While new technologies emerge, human errors always looming. Software supply chain is increasingly complex and intertwined, the security of a service has become paramount to ensuring the integrity of products, safeguarding data privacy, and maintaining operational continuity. In this work, we conducted experiments on the promising open Large Language Models (LLMs) into two main software security challenges: source code language errors and deprecated code, with a focus on their potential to replace conventional static and dynamic security scanners that rely on predefined rules and patterns. Our findings suggest that while LLMs present some unexpected results, they also encounter significant limitations, particularly in memory complexity and the management of new and unfamiliar data patterns. Despite these challenges, the proactive application of LLMs, coupled with extensive security databases and continuous updates, holds the potential to fortify Software Supply Chain (SSC) processes against emerging threats.

cs.CR

Logarithmic Positional Partition Interval Encoding

One requirement of maintaining digital information is storage. With the latest advances in the digital world, new emerging media types have required even more storage space to be kept than before. In fact, in many cases it is required to have larger amounts of storage to keep up with protocols that support more types of information at the same time. In contrast, compression algorithms have been integrated to facilitate the transfer of larger data. Numerical representations are construed as embodiments of information. However, this correct association of a sequence could feasibly be inverted to signify an elongated series of numerals. In this work, a novel mathematical paradigm was introduced to engineer a methodology reliant on iterative logarithmic transformations, finely tuned to numeric sequences. Through this fledgling approach, an intricate interplay of polymorphic numeric manipulations was conducted. By applying repeated logarithmic operations, the data were condensed into a minuscule representation. Approximately thirteen times surpassed the compression method, ZIP. Such extreme compaction, achieved through iterative reduction of expansive integers until they manifested as single-digit entities, conferred a novel sense of informational embodiment. Instead of relegating data to classical discrete encodings, this method transformed them into a quasi-continuous, logarithmically. By contrast, this introduced approach revealed that morphing data into deeply compressed numerical substrata beyond conventional boundaries was feasible. A holistic perspective emerges, validating that numeric data can be recalibrated into ephemeral sequences of logarithmic impressions. It was not merely a matter of reducing digits, but of reinterpreting data through a resolute numeric vantage.

cs.DS