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Zongyi Xu

Publications and source records attributed to Zongyi Xu.

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REFINE: Trajectory Representation Learning via Closed-Loop Transcription -- Extended Version

Trajectory representation learning underpins a wide range of trajectory analytics tasks; however, most existing self-supervised approaches, whether discriminative or generative, adopt an open-loop paradigm, relying on fixed data augmentations or random masking without feedback, which limits their ability to generalize and scale. We propose REFINE, a simple yet effective Representation lEarning Framework vIa closed-loop traNscription rEfinement for trajectory data. Drawing upon feedback control theory, REFINE tightly couples road-network-aware generative reconstruction with feedback-driven contrastive learning, enabling the model to capture fine-grained local movement semantics and global spatio-temporal dependencies without manually designed augmentation views. We further provide a control-theoretic analysis that establishes convergence guarantees for the proposed closed-loop optimization. Extensive experiments on four real-world datasets demonstrate that REFINE consistently outperforms state-of-the-art methods across multiple downstream tasks while remaining computationally efficient and scalable. This paper is an extended version of REFINE: Trajectory Representation Learning via Closed-Loop Transcription, to appear in KDD 2026.

cs.LG

DGCPath: Distribution-Aware Generative Contrastive Framework for Self-supervised Path Representation Learning -- Extended Version

Due to the proliferation of vehicle trajectory data enabled by advanced sensing technologies, path representation learning has become a pivotal task in intelligent transportation systems. Although existing self-supervised approaches have achieved promising performance, their dependence on deterministic contrastive learning paradigms and handcrafted view augmentation strategies inherently restricts their cross-scenario generalization capabilities. To address these limitations, we present DGCPath, an innovative Distribution-aware Generative Contrastive learning framework for Path representation. This framework establishes a synergistic connection between generative modeling and distributional contrastive learning, enabling the acquisition of robust and transferable feature embeddings. Specifically, our framework incorporates: (1) a diffusion-based view generator that autonomously produces semantically coherent yet diverse trajectory views from Gaussian noise; (2) a variational contrastive mechanism that enforces latent feature alignment at the distribution level, transcending conventional instance-wise consistency; and (3) a novel generative cross-supervision module that reinforces view-level consistency through cross-view reconstruction learning. Comprehensive evaluations on three real-world trajectory datasets demonstrate that DGCPath outperforms state-of-the-art baselines on two distinct downstream tasks, validating its enhanced generalization capability and representation effectiveness.

cs.AI

PanFoMa: A Lightweight Foundation Model and Benchmark for Pan-Cancer

Single-cell RNA sequencing (scRNA-seq) is essential for decoding tumor heterogeneity. However, pan-cancer research still faces two key challenges: learning discriminative and efficient single-cell representations, and establishing a comprehensive evaluation benchmark. In this paper, we introduce PanFoMa, a lightweight hybrid neural network that combines the strengths of Transformers and state-space models to achieve a balance between performance and efficiency. PanFoMa consists of a front-end local-context encoder with shared self-attention layers to capture complex, order-independent gene interactions; and a back-end global sequential feature decoder that efficiently integrates global context using a linear-time state-space model. This modular design preserves the expressive power of Transformers while leveraging the scalability of Mamba to enable transcriptome modeling, effectively capturing both local and global regulatory signals. To enable robust evaluation, we also construct a large-scale pan-cancer single-cell benchmark, PanFoMaBench, containing over 3.5 million high-quality cells across 33 cancer subtypes, curated through a rigorous preprocessing pipeline. Experimental results show that PanFoMa outperforms state-of-the-art models on our pan-cancer benchmark (+4.0\%) and across multiple public tasks, including cell type annotation (+7.4\%), batch integration (+4.0\%) and multi-omics integration (+3.1\%). The code is available at https://github.com/Xiaoshui-Huang/PanFoMa.

q-bio.GN

Cross3DReg: Towards a Large-scale Real-world Cross-source Point Cloud Registration Benchmark

Cross-source point cloud registration, which aims to align point cloud data from different sensors, is a fundamental task in 3D vision. However, compared to the same-source point cloud registration, cross-source registration faces two core challenges: the lack of publicly available large-scale real-world datasets for training the deep registration models, and the inherent differences in point clouds captured by multiple sensors. The diverse patterns induced by the sensors pose great challenges in robust and accurate point cloud feature extraction and matching, which negatively influence the registration accuracy. To advance research in this field, we construct Cross3DReg, the currently largest and real-world multi-modal cross-source point cloud registration dataset, which is collected by a rotating mechanical lidar and a hybrid semi-solid-state lidar, respectively. Moreover, we design an overlap-based cross-source registration framework, which utilizes unaligned images to predict the overlapping region between source and target point clouds, effectively filtering out redundant points in the irrelevant regions and significantly mitigating the interference caused by noise in non-overlapping areas. Then, a visual-geometric attention guided matching module is proposed to enhance the consistency of cross-source point cloud features by fusing image and geometric information to establish reliable correspondences and ultimately achieve accurate and robust registration. Extensive experiments show that our method achieves state-of-the-art registration performance. Our framework reduces the relative rotation error (RRE) and relative translation error (RTE) by $63.2\%$ and $40.2\%$, respectively, and improves the registration recall (RR) by $5.4\%$, which validates its effectiveness in achieving accurate cross-source registration.

cs.CV

Non-target Divergence Hypothesis: Toward Understanding Domain Gaps in Cross-Modal Knowledge Distillation

Compared to single-modal knowledge distillation, cross-modal knowledge distillation faces more severe challenges due to domain gaps between modalities. Although various methods have proposed various solutions to overcome these challenges, there is still limited research on how domain gaps affect cross-modal knowledge distillation. This paper provides an in-depth analysis and evaluation of this issue. We first introduce the Non-Target Divergence Hypothesis (NTDH) to reveal the impact of domain gaps on cross-modal knowledge distillation. Our key finding is that domain gaps between modalities lead to distribution differences in non-target classes, and the smaller these differences, the better the performance of cross-modal knowledge distillation. Subsequently, based on Vapnik-Chervonenkis (VC) theory, we derive the upper and lower bounds of the approximation error for cross-modal knowledge distillation, thereby theoretically validating the NTDH. Finally, experiments on five cross-modal datasets further confirm the validity, generalisability, and applicability of the NTDH.

cs.CV

Weakly Supervised LiDAR Semantic Segmentation via Scatter Image Annotation

Weakly supervised LiDAR semantic segmentation has made significant strides with limited labeled data. However, most existing methods focus on the network training under weak supervision, while efficient annotation strategies remain largely unexplored. To tackle this gap, we implement LiDAR semantic segmentation using scatter image annotation, effectively integrating an efficient annotation strategy with network training. Specifically, we propose employing scatter images to annotate LiDAR point clouds, combining a pre-trained optical flow estimation network with a foundation image segmentation model to rapidly propagate manual annotations into dense labels for both images and point clouds. Moreover, we propose ScatterNet, a network that includes three pivotal strategies to reduce the performance gap caused by such annotations. Firstly, it utilizes dense semantic labels as supervision for the image branch, alleviating the modality imbalance between point clouds and images. Secondly, an intermediate fusion branch is proposed to obtain multimodal texture and structural features. Lastly, a perception consistency loss is introduced to determine which information needs to be fused and which needs to be discarded during the fusion process. Extensive experiments on the nuScenes and SemanticKITTI datasets have demonstrated that our method requires less than 0.02% of the labeled points to achieve over 95% of the performance of fully-supervised methods. Notably, our labeled points are only 5% of those used in the most advanced weakly supervised methods.

cs.CV

Hierarchical Point-based Active Learning for Semi-supervised Point Cloud Semantic Segmentation

Impressive performance on point cloud semantic segmentation has been achieved by fully-supervised methods with large amounts of labelled data. As it is labour-intensive to acquire large-scale point cloud data with point-wise labels, many attempts have been made to explore learning 3D point cloud segmentation with limited annotations. Active learning is one of the effective strategies to achieve this purpose but is still under-explored. The most recent methods of this kind measure the uncertainty of each pre-divided region for manual labelling but they suffer from redundant information and require additional efforts for region division. This paper aims at addressing this issue by developing a hierarchical point-based active learning strategy. Specifically, we measure the uncertainty for each point by a hierarchical minimum margin uncertainty module which considers the contextual information at multiple levels. Then, a feature-distance suppression strategy is designed to select important and representative points for manual labelling. Besides, to better exploit the unlabelled data, we build a semi-supervised segmentation framework based on our active strategy. Extensive experiments on the S3DIS and ScanNetV2 datasets demonstrate that the proposed framework achieves 96.5% and 100% performance of fully-supervised baseline with only 0.07% and 0.1% training data, respectively, outperforming the state-of-the-art weakly-supervised and active learning methods. The code will be available at https://github.com/SmiletoE/HPAL.

cs.CV

GenReg: Deep Generative Method for Fast Point Cloud Registration

Accurate and efficient point cloud registration is a challenge because the noise and a large number of points impact the correspondence search. This challenge is still a remaining research problem since most of the existing methods rely on correspondence search. To solve this challenge, we propose a new data-driven registration algorithm by investigating deep generative neural networks to point cloud registration. Given two point clouds, the motivation is to generate the aligned point clouds directly, which is very useful in many applications like 3D matching and search. We design an end-to-end generative neural network for aligned point clouds generation to achieve this motivation, containing three novel components. Firstly, a point multi-perception layer (MLP) mixer (PointMixer) network is proposed to efficiently maintain both the global and local structure information at multiple levels from the self point clouds. Secondly, a feature interaction module is proposed to fuse information from cross point clouds. Thirdly, a parallel and differential sample consensus method is proposed to calculate the transformation matrix of the input point clouds based on the generated registration results. The proposed generative neural network is trained in a GAN framework by maintaining the data distribution and structure similarity. The experiments on both ModelNet40 and 7Scene datasets demonstrate that the proposed algorithm achieves state-of-the-art accuracy and efficiency. Notably, our method reduces $2\times$ in registration error (CD) and $12\times$ running time compared to the state-of-the-art correspondence-based algorithm.

cs.CV

Gaussian Process Regression and Classification using International Classification of Disease Codes as Covariates

International Classification of Disease (ICD) codes are widely used for encoding diagnoses in electronic health records (EHR). Automated methods have been developed over the years for predicting biomedical responses using EHR that borrow information among diagnostically similar patients. Relatively less attention has been paid to developing patient similarity measures that model the structure of ICD codes and the presence of multiple chronic conditions, where a chronic condition is defined as a set of ICD codes. Motivated by this problem, we first develop a type of string kernel function for measuring similarity between a pair of subsets of ICD codes, which uses the definition of chronic conditions. Second, we extend this similarity measure to define a family of covariance functions on subsets of ICD codes. Using this family, we develop Gaussian process (GP) priors for Bayesian nonparametric regression and classification using diagnoses and other demographic information as covariates. Markov chain Monte Carlo (MCMC) algorithms are used for posterior inference and predictions. The proposed methods are free of any tuning parameters and are well-suited for automated prediction of continuous and categorical biomedical responses that depend on chronic conditions. We evaluate the practical performance of our method on EHR data collected from 1660 patients at the University of Iowa Hospitals and Clinics (UIHC) with six different primary cancer sites. Our method has better sensitivity and specificity than its competitors in classifying different primary cancer sites and estimates the marginal associations between chronic conditions and primary cancer sites.

stat.ME

Multilevel active registration for kinect human body scans: from low quality to high quality

Registration of 3D human body has been a challenging research topic for over decades. Most of the traditional human body registration methods require manual assistance, or other auxiliary information such as texture and markers. The majority of these methods are tailored for high-quality scans from expensive scanners. Following the introduction of the low-quality scans from cost-effective devices such as Kinect, the 3D data capturing of human body becomes more convenient and easier. However, due to the inevitable holes, noises and outliers in the low-quality scan, the registration of human body becomes even more challenging. To address this problem, we propose a fully automatic active registration method which deforms a high-resolution template mesh to match the low-quality human body scans. Our registration method operates on two levels of statistical shape models: (1) the first level is a holistic body shape model that defines the basic figure of human; (2) the second level includes a set of shape models for every body part, aiming at capturing more body details. Our fitting procedure follows a coarse-to-fine approach that is robust and efficient. Experiments show that our method is comparable with the state-of-the-art methods.

cs.GR