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Zvi Rosen

Publications and source records attributed to Zvi Rosen.

At least 19 recordsLinked to original sources

Linearizing Algebraic Matroids

Although algebraic matroids were discovered in the 1930s, interest in them was largely dormant until their recent use in applications of algebraic geometry. Because nonlinear algebra is computationally challenging, it is easier to work with an isomorphic linear matroid if one exists. We describe an explicit construction that produces a linear representation over an algebraically closed field of characteristic zero starting with the data used in applications. We will also discuss classical examples of algebraic matroids in the modern language of polynomial ideals, illustrating how the existence of an isomorphic linear matroid depends on properties of the field.

math.AC

Angular constraints on planar frameworks

Consider a collection of points in the plane and the sets of slopes or directions of the lines between pairs of points. It is known that the algebraic matroid on the set of direction constraints between the points is equivalent to the algebraic matroid on the set of distances between the points. This is the well-studied generic 2-dimensional rigidity matroid of a graph. This article studies a higher-level construction built on the slope data: an angle constraint system obtained by prescribing relationships between pairs of slopes. The central question we analyze is: when is an angle system rigid, in the sense that every nontrivial motion alters one of the fixed angles? We formulate the problem in matricial terms for certain edge-colored graphs, finding precise necessary conditions for when such edge-colored graphs are rigid, and a combinatorial characterization of generic rigidity for a special case. We also prove the validity of an equivalent formulation of the angle matroid as the algebraic matroid of a field extension.

math.CO

Oriented Matroids and Combinatorial Neural Codes

A combinatorial neural code $\mathscr C\subseteq 2^{[n]}$ is convex if it arises as the intersection pattern of convex open subsets of $\mathbb R^d$. We relate the emerging theory of convex neural codes to the established theory of oriented matroids, both categorically and with respect to geometry and computational complexity. On the categorical side, we show that the map taking an acyclic oriented matroid to the code of positive parts of its topes is a faithful functor. We adapt the oriented matroid ideal introduced by Novik, Postnikov, and Sturmfels into a functor from the category of oriented matroids to the category of rings; then, we show that the resulting ring maps naturally to the neural ring of the matroid's neural code. For geometry and computational complexity, we show that a code has a realization with convex polytopes if and only if it lies below the code of a representable oriented matroid in the partial order of codes introduced by Jeffs. We show that previously published examples of non-convex codes do not lie below any oriented matroids, and we construct examples of non-convex codes lying below non-representable oriented matroids. By way of this construction, we can apply Mnëv-Sturmfels universality to show that deciding whether a combinatorial code is convex is NP-hard.

math.CO

On the Number of Equilibria Balancing Newtonian Point Masses with a Central Force

We consider the critical points (equilibria) of a planar potential generated by $n$ Newtonian point masses augmented with a quadratic term (such as arises from a centrifugal effect). Particular cases of this problem have been considered previously in studies of the circular restricted $n$-body problem. We show that the number of equilibria is finite for a generic set of parameters, and we establish estimates for the number of equilibria. We prove that the number of equilibria is bounded below by $n+1$, and we provide examples to show that this lower bound is sharp. We prove an upper bound on the number of equilibria that grows exponentially in $n$. In order to establish a lower bound on the maximum number of equilibria, we analyze a class of examples, referred to as ``ring configurations'', consisting of $n-1$ equal masses positioned at vertices of a regular polygon with an additional mass located at the center. Previous numerical observations indicate that these configurations can produce as many as $5n-5$ equilibria. We verify analytically that the ring configuration has at least $5n-5$ equilibria when the central mass is sufficiently small. We conjecture that the maximum number of equilibria grows linearly with the number of point masses. We also discuss some mathematical similarities to other equilibrium problems in mathematical physics, namely, Maxwell's problem from electrostatics and the image counting problem from gravitational lensing.

math-ph

Sparse moments of univariate step functions and allele frequency spectra

We study the univariate moment problem of piecewise-constant density functions on the interval $[0,1]$ and its consequences for an inference problem in population genetics. We show that, up to closure, any collection of $n$ moments is achieved by a step function with at most $n-1$ breakpoints and that this bound is tight. We use this to show that any point in the $n$th coalescence manifold in population genetics can be attained by a piecewise constant population history with at most $n-2$ changes. Both the moment cones and the coalescence manifold are projected spectrahedra and we describe the problem of finding a nearest point on them as a semidefinite program.

math.PR

Hyperplane Neural Codes and the Polar Complex

Hyperplane codes are a class of convex codes that arise as the output of a one layer feed-forward neural network. Here we establish several natural properties of stable hyperplane codes in terms of the {\it polar complex} of the code, a simplicial complex associated to any combinatorial code. We prove that the polar complex of a stable hyperplane code is shellable and show that most currently known properties of the hyperplane codes follow from the shellability of the appropriate polar complex.

q-bio.NC

Algebraic matroids in action

In recent years, various notions of algebraic independence have emerged as a central and unifying theme in a number of areas of applied mathematics, including algebraic statistics and the rigidity theory of bar-and-joint frameworks. In each of these settings the fundamental problem is to determine the extent to which certain unknowns depend algebraically on given data. This has, in turn, led to a resurgence of interest in algebraic matroids, which are the combinatorial formalism for algebraic (in)dependence. We give a self-contained introduction to algebraic matroids together with examples highlighting their potential application.

math.CO

Algebraic signatures of convex and non-convex codes

A convex code is a binary code generated by the pattern of intersections of a collection of open convex sets in some Euclidean space. Convex codes are relevant to neuroscience as they arise from the activity of neurons that have convex receptive fields. In this paper, we use algebraic methods to determine if a code is convex. Specifically, we use the neural ideal of a code, which is a generalization of the Stanley-Reisner ideal. Using the neural ideal together with its standard generating set, the canonical form, we provide algebraic signatures of certain families of codes that are non-convex. We connect these signatures to the precise conditions on the arrangement of sets that prevent the codes from being convex. Finally, we also provide algebraic signatures for some families of codes that are convex, including the class of intersection-complete codes. These results allow us to detect convexity and non-convexity in a variety of situations, and point to some interesting open questions.

q-bio.NC

Geometry of the sample frequency spectrum and the perils of demographic inference

The sample frequency spectrum (SFS), which describes the distribution of mutant alleles in a sample of DNA sequences, is a widely used summary statistic in population genetics. The expected SFS has a strong dependence on the historical population demography and this property is exploited by popular statistical methods to infer complex demographic histories from DNA sequence data. Most, if not all, of these inference methods exhibit pathological behavior, however. Specifically, they often display runaway behavior in optimization, where the inferred population sizes and epoch durations can degenerate to 0 or diverge to infinity, and show undesirable sensitivity of the inferred demography to perturbations in the data. The goal of this paper is to provide theoretical insights into why such problems arise. To this end, we characterize the geometry of the expected SFS for piecewise-constant demographic histories and use our results to show that the aforementioned pathological behavior of popular inference methods is intrinsic to the geometry of the expected SFS. We provide explicit descriptions and visualizations for a toy model with sample size 4, and generalize our intuition to arbitrary sample sizes n using tools from convex and algebraic geometry. We also develop a universal characterization result which shows that the expected SFS of a sample of size n under an arbitrary population history can be recapitulated by a piecewise-constant demography with only k(n) epochs, where k(n) is between n/2 and 2n-1. The set of expected SFS for piecewise-constant demographies with fewer than k(n) epochs is open and non-convex, which causes the above phenomena for inference from data.

q-bio.PE

Convex Neural Codes in Dimension 1

Neural codes are collections of binary strings motivated by patterns of neural activity. In this paper, we study algorithmic and enumerative aspects of convex neural codes in dimension 1 (i.e. on a line or a circle). We use the theory of consecutive-ones matrices to obtain some structural and algorithmic results; we use generating functions to obtain enumerative results.

math.CO

What makes a neural code convex?

Neural codes allow the brain to represent, process, and store information about the world. Combinatorial codes, comprised of binary patterns of neural activity, encode information via the collective behavior of populations of neurons. A code is called convex if its codewords correspond to regions defined by an arrangement of convex open sets in Euclidean space. Convex codes have been observed experimentally in many brain areas, including sensory cortices and the hippocampus, where neurons exhibit convex receptive fields. What makes a neural code convex? That is, how can we tell from the intrinsic structure of a code if there exists a corresponding arrangement of convex open sets? In this work, we provide a complete characterization of local obstructions to convexity. This motivates us to define max intersection-complete codes, a family guaranteed to have no local obstructions. We then show how our characterization enables one to use free resolutions of Stanley-Reisner ideals in order to detect violations of convexity. Taken together, these results provide a significant advance in understanding the intrinsic combinatorial properties of convex codes.

q-bio.NC

The geometry of rank-one tensor completion

The geometry of the set of restrictions of rank-one tensors to some of their coordinates is studied. This gives insight into the problem of rank-one completion of partial tensors. Particular emphasis is put on the semialgebraic nature of the problem, which arises for real tensors with constraints on the parameters. The algebraic boundary of the completable region is described for tensors parametrized by probability distributions and where the number of observed entries equals the number of parameters. If the observations are on the diagonal of a tensor of format $d\times\dots\times d$, the complete semialgebraic description of the completable region is found.

math.AG

Algebraic Tools for the Analysis of State Space Models

We present algebraic techniques to analyze state space models in the areas of structural identifiability, observability, and indistinguishability. While the emphasis is on surveying existing algebraic tools for studying ODE systems, we also present a variety of new results. In particular: on structural identifiability, we present a method using linear algebra to find identifiable functions of the parameters of a model for unidentifiable models. On observability, we present techniques using Gröbner bases and algebraic matroids to test algebraic observability of state space models. On indistinguishability, we present a sufficient condition for distinguishability using computational algebra and demonstrate testing indistinguishability.

math.OC

Matrix Completion for the Independence Model

We investigate the problem of completing partial matrices to rank-one matrices in the standard simplex. The motivation for studying this problem comes from statistics: A lack of eligible completion can provide a falsification test for partial observations to come from the independence model. For each pattern of specified entries, we give equations and inequalities which are satisfied if and only if an eligible completion exists. We also describe the set of valid completions, and we optimize over this set.

math.ST

Line arrangements modeling curves of high degree: equations, syzygies and secants

We study curves consisting of unions of projective lines whose intersections are given by graphs. Under suitable hypotheses on the graph, these so-called \emph{graph curves} can be embedded in projective space as line arrangements. We discuss property $N_p$ for these embeddings and are able to produce products of linear forms that generate the ideal in certain cases. We also briefly discuss questions regarding the higher-dimensional subspace arrangements obtained by taking the secant varieties of graph curves.

math.AG

Algebraic Systems Biology: A Case Study for the Wnt Pathway

Steady state analysis of dynamical systems for biological networks give rise to algebraic varieties in high-dimensional spaces whose study is of interest in their own right. We demonstrate this for the shuttle model of the Wnt signaling pathway. Here the variety is described by a polynomial system in 19 unknowns and 36 parameters. Current methods from computational algebraic geometry and combinatorics are applied to analyze this model.

q-bio.MN

Parameter-free methods distinguish Wnt pathway models and guide design of experiments

The canonical Wnt signaling pathway, mediated by $β$-catenin, is crucially involved in development, adult stem cell tissue maintenance and a host of diseases including cancer. We undertake analysis of different mathematical models of Wnt from the literature, and compare them to a new mechanistic model of Wnt signaling that targets spatial localization of key molecules. Using Bayesian methods we infer parameters for each of the models to mammalian Wnt signaling data and find that all models can fit this time course. We are able to overcome this lack of data by appealing to algebraic methods (concepts from chemical reaction network theory and matroid theory) to analyze the models without recourse to specific parameter values. These approaches provide insight into Wnt signaling: The new model (unlike any other investigated) permits a bistable switch in the system via control of shuttling and degradation parameters, corresponding to stem-like vs committed cell states in the differentiation hierarchy. Our analysis also identifies groups of variables that must be measured to fully characterize and discriminate between competing models, and thus serves as a guide for performing minimal experiments for model comparison.

q-bio.QM

Computing Algebraic Matroids

An affine variety induces the structure of an algebraic matroid on the set of coordinates of the ambient space. The matroid has two natural decorations: a circuit polynomial attached to each circuit, and the degree of the projection map to each base, called the base degree. Decorated algebraic matroids can be computed via symbolic computation using Groebner bases, or through linear algebra in the space of differentials (with decorations calculated using numerical algebraic geometry). Both algorithms are developed here. Failure of the second algorithm occurs on a subvariety called the non-matroidal or NM- locus. Decorated algebraic matroids have widespread relevance anywhere that coordinates have combinatorial significance. Examples are computed from applied algebra, in algebraic statistics and chemical reaction network theory, as well as more theoretical examples from algebraic geometry and matroid theory.

math.CO