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$Γ$-Convergence of an Ambrosio-Tortorelli approximation scheme for image segmentation

Given an image $u_0$, the aim of minimising the Mumford-Shah functional is to find a decomposition of the image domain into sub-domains and a piecewise smooth approximation $u$ of $u_0$ such that $u$ varies smoothly within each sub-domain. Since the Mumford-Shah functional is highly non-smooth, regularizations such as the Ambrosio-Tortorelli approximation can be considered which is one of the most computationally efficient approximations of the Mumford-Shah functional for image segmentation. While very impressive numerical results have been achieved in a large range of applications when minimising the functional, no analytical results are currently available for minimizers of the functional in the piecewise smooth setting, and this is the goal of this work. Our main result is the $Γ$-convergence of the Ambrosio-Tortorelli approximation of the Mumford-Shah functional for piecewise smooth approximations. This requires the introduction of an appropriate function space. As a consequence of our $Γ$-convergence result, we can infer the convergence of minimizers of the respective functionals.

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FFPN: Fourier Feature Pyramid Network for Ultrasound Image Segmentation

Ultrasound (US) image segmentation is an active research area that requires real-time and highly accurate analysis in many scenarios. The detect-to-segment (DTS) frameworks have been recently proposed to balance accuracy and efficiency. However, existing approaches may suffer from inadequate contour encoding or fail to effectively leverage the encoded results. In this paper, we introduce a novel Fourier-anchor-based DTS framework called Fourier Feature Pyramid Network (FFPN) to address the aforementioned issues. The contributions of this paper are two fold. First, the FFPN utilizes Fourier Descriptors to adequately encode contours. Specifically, it maps Fourier series with similar amplitudes and frequencies into the same layer of the feature map, thereby effectively utilizing the encoded Fourier information. Second, we propose a Contour Sampling Refinement (CSR) module based on the contour proposals and refined features produced by the FFPN. This module extracts rich features around the predicted contours to further capture detailed information and refine the contours. Extensive experimental results on three large and challenging datasets demonstrate that our method outperforms other DTS methods in terms of accuracy and efficiency. Furthermore, our framework can generalize well to other detection or segmentation tasks.

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From Denoising Training to Test-Time Adaptation: Enhancing Domain Generalization for Medical Image Segmentation

In medical image segmentation, domain generalization poses a significant challenge due to domain shifts caused by variations in data acquisition devices and other factors. These shifts are particularly pronounced in the most common scenario, which involves only single-source domain data due to privacy concerns. To address this, we draw inspiration from the self-supervised learning paradigm that effectively discourages overfitting to the source domain. We propose the Denoising Y-Net (DeY-Net), a novel approach incorporating an auxiliary denoising decoder into the basic U-Net architecture. The auxiliary decoder aims to perform denoising training, augmenting the domain-invariant representation that facilitates domain generalization. Furthermore, this paradigm provides the potential to utilize unlabeled data. Building upon denoising training, we propose Denoising Test Time Adaptation (DeTTA) that further: (i) adapts the model to the target domain in a sample-wise manner, and (ii) adapts to the noise-corrupted input. Extensive experiments conducted on widely-adopted liver segmentation benchmarks demonstrate significant domain generalization improvements over our baseline and state-of-the-art results compared to other methods. Code is available at https://github.com/WenRuxue/DeTTA.

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Collaborative Position Reasoning Network for Referring Image Segmentation

Given an image and a natural language expression as input, the goal of referring image segmentation is to segment the foreground masks of the entities referred by the expression. Existing methods mainly focus on interactive learning between vision and language to enhance the multi-modal representations for global context reasoning. However, predicting directly in pixel-level space can lead to collapsed positioning and poor segmentation results. Its main challenge lies in how to explicitly model entity localization, especially for non-salient entities. In this paper, we tackle this problem by executing a Collaborative Position Reasoning Network (CPRN) via the proposed novel Row-and-Column interactive (RoCo) and Guided Holistic interactive (Holi) modules. Specifically, RoCo aggregates the visual features into the row- and column-wise features corresponding two directional axes respectively. It offers a fine-grained matching behavior that perceives the associations between the linguistic features and two decoupled visual features to perform position reasoning over a hierarchical space. Holi integrates features of the two modalities by a cross-modal attention mechanism, which suppresses the irrelevant redundancy under the guide of positioning information from RoCo. Thus, with the incorporation of RoCo and Holi modules, CPRN captures the visual details of position reasoning so that the model can achieve more accurate segmentation. To our knowledge, this is the first work that explicitly focuses on position reasoning modeling. We also validate the proposed method on three evaluation datasets. It consistently outperforms existing state-of-the-art methods.

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Q2A: Querying Implicit Fully Continuous Feature Pyramid to Align Features for Medical Image Segmentation

Recent medical image segmentation methods apply implicit neural representation (INR) to the decoder for achieving a continuous coordinate decoding to tackle the drawback of conventional discrete grid-based data representations. However, the INR-based decoder cannot well handle the feature misalignment problem brought about by the naive latent code acquisition strategy in INR. Although there exist many feature alignment works, they all adopt a progressive multi-step aligning paradigm on a discrete feature pyramid, which is incompatible with the continuous one-step characteristics of INR-based decoder, and thus fails to be the solution. Therefore, we propose Q2A, a novel one-step query-based aligning paradigm, to solve the feature misalignment problem in the INR-based decoder. Specifically, for each target coordinate, Q2A first generates several queries depicting the spatial offsets and the cell resolutions of the contextual features aligned to the coordinate, then calculates the corresponding aligned features by feeding the queries into a novel implicit fully continuous feature pyramid (FCFP), finally fuses the aligned features to predict the class distribution. In FCFP, we further propose a novel universal partition-and-aggregate strategy (P&A) to replace the naive interpolation strategy for latent code acquisition in INR, which mitigates the information loss problem that occurs when the query cell resolution is relatively large and achieves an effective feature decoding at arbitrary continuous resolution. We conduct extensive experiments on two medical datasets, i.e. Glas and Synapse, and a universal dataset, i.e. Cityscapes, and they show the superiority of the proposed Q2A.

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pFLFE: Cross-silo Personalized Federated Learning via Feature Enhancement on Medical Image Segmentation

In medical image segmentation, personalized cross-silo federated learning (FL) is becoming popular for utilizing varied data across healthcare settings to overcome data scarcity and privacy concerns. However, existing methods often suffer from client drift, leading to inconsistent performance and delayed training. We propose a new framework, Personalized Federated Learning via Feature Enhancement (pFLFE), designed to mitigate these challenges. pFLFE consists of two main stages: feature enhancement and supervised learning. The first stage improves differentiation between foreground and background features, and the second uses these enhanced features for learning from segmentation masks. We also design an alternative training approach that requires fewer communication rounds without compromising segmentation quality, even with limited communication resources. Through experiments on three medical segmentation tasks, we demonstrate that pFLFE outperforms the state-of-the-art methods.

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PraNet-V2: Dual-Supervised Reverse Attention for Medical Image Segmentation

Accurate medical image segmentation is essential for effective diagnosis and treatment. Previously, PraNet-V1 was proposed to enhance polyp segmentation by introducing a reverse attention (RA) module that utilizes background information. However, PraNet-V1 struggles with multi-class segmentation tasks. To address this limitation, we propose PraNet-V2, which, compared to PraNet-V1, effectively performs a broader range of tasks including multi-class segmentation. At the core of PraNet-V2 is the Dual-Supervised Reverse Attention (DSRA) module, which incorporates explicit background supervision, independent background modeling, and semantically enriched attention fusion. Our PraNet-V2 framework demonstrates strong performance on four polyp segmentation datasets. Additionally, by integrating DSRA to iteratively enhance foreground segmentation results in three state-of-the-art semantic segmentation models, we achieve up to a 1.36% improvement in mean Dice score. Code is available at: https://github.com/ai4colonoscopy/PraNet-V2/tree/main/binary_seg/jittor.

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Exploiting Unlabeled Structures through Task Consistency Training for Versatile Medical Image Segmentation

Versatile medical image segmentation (VMIS) targets the segmentation of multiple classes, while obtaining full annotations for all classes is often impractical due to the time and labor required. Leveraging partially labeled datasets (PLDs) presents a promising alternative; however, current VMIS approaches face significant class imbalance due to the unequal category distribution in PLDs. Existing methods attempt to address this by generating pseudo-full labels. Nevertheless, these typically require additional models and often result in potential performance degradation from label noise. In this work, we introduce a Task Consistency Training (TCT) framework to address class imbalance without requiring extra models. TCT includes a backbone network with a main segmentation head (MSH) for multi-channel predictions and multiple auxiliary task heads (ATHs) for task-specific predictions. By enforcing a consistency constraint between the MSH and ATH predictions, TCT effectively utilizes unlabeled anatomical structures. To avoid error propagation from low-consistency, potentially noisy data, we propose a filtering strategy to exclude such data. Additionally, we introduce a unified auxiliary uncertainty-weighted loss (UAUWL) to mitigate segmentation quality declines caused by the dominance of specific tasks. Extensive experiments on eight abdominal datasets from diverse clinical sites demonstrate our approach's effectiveness.

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Unified Start, Personalized End: Progressive Pruning for Efficient 3D Medical Image Segmentation

3D medical image segmentation often faces heavy resource and time consumption, limiting its scalability and rapid deployment in clinical environments. Existing efficient segmentation models are typically static and manually designed prior to training, which restricts their adaptability across diverse tasks and makes it difficult to balance performance with resource efficiency. In this paper, we propose PSP-Seg, a progressive pruning framework that enables dynamic and efficient 3D segmentation. PSP-Seg begins with a redundant model and iteratively prunes redundant modules through a combination of block-wise pruning and a functional decoupling loss. We evaluate PSP-Seg on five public datasets, benchmarking it against seven state-of-the-art models and six efficient segmentation models. Results demonstrate that the lightweight variant, PSP-Seg-S, achieves performance on par with nnU-Net while reducing GPU memory usage by 42-45%, training time by 29-48%, and parameter number by 83-87% across all datasets. These findings underscore PSP-Seg's potential as a cost-effective yet high-performing alternative for widespread clinical application.

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K-Prism: A Knowledge-Guided and Prompt Integrated Universal Medical Image Segmentation Model

Medical image segmentation is fundamental to clinical decision-making, yet existing models remain fragmented. They are usually trained on single knowledge sources and specific to individual tasks, modalities, or organs. This fragmentation contrasts sharply with clinical practice, where experts seamlessly integrate diverse knowledge: anatomical priors from training, exemplar-based reasoning from reference cases, and iterative refinement through real-time interaction. We present $\textbf{K-Prism}$, a unified segmentation framework that mirrors this clinical flexibility by systematically integrating three knowledge paradigms: (i) $\textit{semantic priors}$ learned from annotated datasets, (ii) $\textit{in-context knowledge}$ from few-shot reference examples, and (iii) $\textit{interactive feedback}$ from user inputs like clicks or scribbles. Our key insight is that these heterogeneous knowledge sources can be encoded into a dual-prompt representation: 1-D sparse prompts defining $\textit{what}$ to segment and 2-D dense prompts indicating $\textit{where}$ to attend, which are then dynamically routed through a Mixture-of-Experts (MoE) decoder. This design enables flexible switching between paradigms and joint training across diverse tasks without architectural modifications. Comprehensive experiments on 18 public datasets spanning diverse modalities (CT, MRI, X-ray, pathology, ultrasound, etc.) demonstrate that K-Prism achieves state-of-the-art performance across semantic, in-context, and interactive segmentation settings.

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DTEA: Dynamic Topology Weaving and Instability-Driven Entropic Attenuation for Medical Image Segmentation

In medical image segmentation, skip connections are used to merge global context and reduce the semantic gap between encoder and decoder. Current methods often struggle with limited structural representation and insufficient contextual modeling, affecting generalization in complex clinical scenarios. We propose the DTEA model, featuring a new skip connection framework with the Semantic Topology Reconfiguration (STR) and Entropic Perturbation Gating (EPG) modules. STR reorganizes multi-scale semantic features into a dynamic hypergraph to better model cross-resolution anatomical dependencies, enhancing structural and semantic representation. EPG assesses channel stability after perturbation and filters high-entropy channels to emphasize clinically important regions and improve spatial attention. Extensive experiments on three benchmark datasets show our framework achieves superior segmentation accuracy and better generalization across various clinical settings. The code is available at \href{https://github.com/LWX-Research/DTEA}{https://github.com/LWX-Research/DTEA}.

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SpectralMamba-UNet: Frequency-Disentangled State Space Modeling for Texture-Structure Consistent Medical Image Segmentation

Accurate medical image segmentation requires effective modeling of both global anatomical structures and fine-grained boundary details. Recent state space models (e.g., Vision Mamba) offer efficient long-range dependency modeling. However, their one-dimensional serialization weakens local spatial continuity and high-frequency representation. To this end, we propose SpectralMamba-UNet, a novel frequency-disentangled framework to decouple the learning of structural and textural information in the spectral domain. Our Spectral Decomposition and Modeling (SDM) module applies discrete cosine transform to decompose low- and high-frequency features, where low frequency contributes to global contextual modeling via a frequency-domain Mamba and high frequency preserves boundary-sensitive details. To balance spectral contributions, we introduce a Spectral Channel Reweighting (SCR) mechanism to form channel-wise frequency-aware attention, and a Spectral-Guided Fusion (SGF) module to achieve adaptively multi-scale fusion in the decoder. Experiments on five public benchmarks demonstrate consistent improvements across diverse modalities and segmentation targets, validating the effectiveness and generalizability of our approach.

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FedEU: Evidential Uncertainty-Driven Federated Fine-Tuning of Vision Foundation Models for Remote Sensing Image Segmentation

Remote sensing image segmentation (RSIS) in federated environments has gained increasing attention because it enables collaborative model training across distributed datasets without sharing raw imagery or annotations. Federated RSIS combined with parameter-efficient fine-tuning (PEFT) can unleash the generalization power of pretrained foundation models for real-world applications, with minimal parameter aggregation and communication overhead. However, the dynamic adaptation of pretrained models to heterogeneous client data inevitably increases update uncertainty and compromises the reliability of collaborative optimization due to the lack of uncertainty estimation for each local model. To bridge this gap, we present FedEU, a federated optimization framework for fine-tuning RSIS models driven by evidential uncertainty. Specifically, personalized evidential uncertainty modeling is introduced to quantify epistemic variations of local models and identify high-risk areas under local data distributions. Furthermore, the client-specific feature embedding (CFE) is exploited to enhance channel-aware feature representation while preserving client-specific properties through personalized attention and an element-aware parameter update approach. These uncertainty estimates are uploaded to the server to enable adaptive global aggregation via a Top-k uncertainty-guided weighting (TUW) strategy, which mitigates the impact of distribution shifts and unreliable updates. Extensive experiments on three large-scale heterogeneous datasets demonstrate the superior performance of FedEU. More importantly, FedEU enables balanced model adaptation across diverse clients by explicitly reducing prediction uncertainty, resulting in more robust and reliable federated outcomes. The source codes will be available at https://github.com/zxk688/FedEU.

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DCAU-Net: Differential Cross Attention and Channel-Spatial Feature Fusion for Medical Image Segmentation

Accurate medical image segmentation requires effective modeling of both long-range dependencies and fine-grained boundary details. While transformers mitigate the issue of insufficient semantic information arising from the limited receptive field inherent in convolutional neural networks, they introduce new challenges: standard self-attention incurs quadratic computational complexity and often assigns non-negligible attention weights to irrelevant regions, diluting focus on discriminative structures and ultimately compromising segmentation accuracy. Existing attention variants, although effective in reducing computational complexity, fail to suppress redundant computation and inadvertently impair global context modeling. Furthermore, conventional fusion strategies in encoder-decoder architectures, typically based on simple concatenation or summation, can not adaptively integrate high-level semantic information with low-level spatial details. To address these limitations, we propose DCAU-Net, a novel yet efficient segmentation framework with two key ideas. First, a new Differential Cross Attention (DCA) is designed to compute the difference between two independent softmax attention maps to adaptively highlight discriminative structures. By replacing pixel-wise key and value tokens with window-level summary tokens, DCA dramatically reduces computational complexity without sacrificing precision. Second, a Channel-Spatial Feature Fusion (CSFF) strategy is introduced to adaptively recalibrate features from skip connections and up-sampling paths through using sequential channel and spatial attention, effectively suppressing redundant information and amplifying salient cues. Experiments on two public benchmarks demonstrate that DCAU-Net achieves competitive performance with enhanced segmentation accuracy and robustness.

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Venice-H1: Failure-Aware Query Re-Ranking with Multi-Scale Grid Signatures for Referring Image Segmentation

Modern Referring Image Segmentation (RIS) systems generate multiple candidate masks per expression but rely on a simple heuristic--typically the argmax detection score--to select the final output. We identify query selection as a failure-case bottleneck: although heuristic selection succeeds on 82-93% of samples, the residual 7-18% of failures dominate the error budget, leaving a best-query selection gap of 3-11% mIoU. We introduce Venice-H1, a lightweight, backbone-decoupled post-hoc re-ranking module that encodes each candidate through multi-scale grid signatures--compact spatial descriptors pooled onto 4x4, 8x8, and 16x16 grids--and feeds them to a Transformer-based re-ranker with a Failure Gate (ROCAUC 0.78-0.82) that intervenes only when the default choice is likely suboptimal. Instantiated on DeRIS-L and DeRIS-B, Venice-H1 achieves delta_fail of +1.40 and +0.89 mIoU with strictly positive 95% CIs on all 16/16 (split, backbone) pairs and harmful-switch rates below 0.53%. Zero-shot transfer to medical referring segmentation (MS-CXR, M3D-RefSeg-2D) yields +1.16 and +0.51 mIoU without RIS-backbone fine-tuning. The module adds approximately 11.3M parameters and under 1 ms latency.

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KANResDiff: Learning Local Residual Diffusion via Kolmogorov-Arnold Network for Ambiguous Medical Image Segmentation

Ambiguous medical image segmentation aims to provide a series of diverse but plausible segmentation hypotheses. However, existing methods introduce stochasticity in a fixed and pre-defined manner, failing to form a progressive semantic modeling process. To address these challenges, we propose KANResDiff to learn local residual diffusion with Kolmogorov-Arnold Network, thereby assigning distinct roles across stages for ambiguity modeling. Specifically, we propose Independent Time Encoding that offers spline-based time embeddings instead of linear ones from MLPs, which enhances the independence across inference stages and assigns progressive semantic roles to different stages. We propose Residual Schrodinger Bridge that injects deterministic residual prior with learnable weights by constructing local Schrodinger Bridge instead of following manually settings, achieving a flexible deterministic-stochastic interaction and stage-aware ambiguity modeling thanks to local optimal diffusion path. Extensive experimental results on two public datasets demonstrate that KANResDiff achieves SOTA performance on GED and HM-IoU, with maximum improvements of 16.8% and 7.7%, respectively, while maintaining competitive performance on the MDM metric. Source code is available at https://github.com/PerceptionComputingLab/KANResDiff.

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Interactive Binary Image Segmentation with Edge Preservation

Binary image segmentation plays an important role in computer vision and has been widely used in many applications such as image and video editing, object extraction, and photo composition. In this paper, we propose a novel interactive binary image segmentation method based on the Markov Random Field (MRF) framework and the fast bilateral solver (FBS) technique. Specifically, we employ the geodesic distance component to build the unary term. To ensure both computation efficiency and effective responsiveness for interactive segmentation, superpixels are used in computing geodesic distances instead of pixels. Furthermore, we take a bilateral affinity approach for the pairwise term in order to preserve edge information and denoise. Through the alternating direction strategy, the MRF energy minimization problem is divided into two subproblems, which then can be easily solved by steepest gradient descent (SGD) and FBS respectively. Experimental results on the VGG interactive image segmentation dataset show that the proposed algorithm outperforms several state-of-the-art ones, and in particular, it can achieve satisfactory edge-smooth segmentation results even when the foreground and background color appearances are quite indistinctive.

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Continual Learning for Image Segmentation with Dynamic Query

Image segmentation based on continual learning exhibits a critical drop of performance, mainly due to catastrophic forgetting and background shift, as they are required to incorporate new classes continually. In this paper, we propose a simple, yet effective Continual Image Segmentation method with incremental Dynamic Query (CISDQ), which decouples the representation learning of both old and new knowledge with lightweight query embedding. CISDQ mainly includes three contributions: 1) We define dynamic queries with adaptive background class to exploit past knowledge and learn future classes naturally. 2) CISDQ proposes a class/instance-aware Query Guided Knowledge Distillation strategy to overcome catastrophic forgetting by capturing the inter-class diversity and intra-class identity. 3) Apart from semantic segmentation, CISDQ introduce the continual learning for instance segmentation in which instance-wise labeling and supervision are considered. Extensive experiments on three datasets for two tasks (i.e., continual semantic and instance segmentation are conducted to demonstrate that CISDQ achieves the state-of-the-art performance, specifically, obtaining 4.4% and 2.9% mIoU improvements for the ADE 100-10 (6 steps) setting and ADE 100-5 (11 steps) setting.

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