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arXiv · 0802.1107

Quantized current blockade and hydrodynamic correlations in biopolymer translocation through nanopores: evidence from multiscale simulations

Massimo Bernaschi·Simone Melchionna·Sauro Succi·Maria Fyta·Efthimios Kaxiras
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Abstract

We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent, using an innovative multi-scale methodology which treats the biopolymer at the microscopic scale as combined with a self-consistent mesoscopic description for the solvent fluid dynamics. We report evidence for quantized current blockade depending on the folding configuration and offer detailed information on the role of hydrodynamic correlations in speeding-up the translocation process.

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Massimo Bernaschi, Simone Melchionna, Sauro Succi, Maria Fyta, Efthimios Kaxiras. 2008-02-08. Quantized current blockade and hydrodynamic correlations in biopolymer translocation through nanopores: evidence from multiscale simulations. https://doi.org/10.1021/nl073251f

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