Silicon-based nanochannel glucose sensor

Xihua Wang; Yu Chen; Katherine A. Gibney; Shyamsunder Erramilli; Pritiraj Mohanty

doi:10.1063/1.2832648

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arXiv · 0802.1721

Silicon-based nanochannel glucose sensor

Xihua Wang·Yu Chen·Katherine A. Gibney·Shyamsunder Erramilli·Pritiraj Mohanty

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Abstract

Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The differential conductance of silicon nanowires, tuned with source-drain bias voltage, is demonstrated to be sensitive to the biocatalyzed oxidation of glucose. The glucose biosensor response is linear in the 0.5-8 mM concentration range with 3-5 min response time. This silicon nanochannel-based glucose biosensor technology offers the possibility of high density, high quality glucose biosensor integration with silicon-based circuitry.

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BibTeX RIS

Xihua Wang, Yu Chen, Katherine A. Gibney, Shyamsunder Erramilli, Pritiraj Mohanty. 2008-02-12. Silicon-based nanochannel glucose sensor. https://doi.org/10.1063/1.2832648

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