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Pritiraj Mohanty

Publications and source records attributed to Pritiraj Mohanty.

At least 19 recordsLinked to original sources

Radio Frequency Field-Induced Enhancement of Detection Sensitivity in Silicon Nanowire Sensors

Sensitive biomarker detection in physiological fluids is often limited by Debye screening, which suppresses electrostatic signals at sensor surfaces. Here we report a sensing approach based on flexoelectric resonance in silicon nanowire field-effect transistors. An applied radiofrequency field induces strain gradients in the nanowires, generating flexoelectric polarization that is amplified at resonant frequencies. This effect enhances the sensitivity of conductance measurements to small surface charge variations associated with biomolecular binding. Using C-reactive protein as a model biomarker, we observe an order-of-magnitude improvement in detection sensitivity compared to conventional operation, with a 62% conductance increase versus 30% without radiofrequency modulation. The high-frequency field also perturbs the electrical double layer, reducing Debye screening in high-ionic-strength environments. These combined effects enable direct biomarker detection without sample dilution. This work establishes flexoelectric resonance as a general strategy for improving nanoscale biosensing performance in physiologically relevant conditions.

cond-mat.mtrl-sci↗

Measurement of nonlinear piezoelectric coefficients using a micromechanical resonator

We describe and demonstrate a method by which the nonlinear piezoelectric properties of a piezoelectric material may be measured by detecting the force that it applies on a suspended micromechanical resonator at one of its mechanical resonance frequencies. Resonators are used in countless applications; this method could provide a means for better-characterizing material behaviors within real MEMS devices. Further, special devices can be designed to probe this nonlinear behavior at specific frequencies with enhanced signal sizes. The resonators used for this experiment are actuated using a 1-$μ$m-thick layer of aluminum nitride. When driven at large amplitudes, the piezoelectric layer generates harmonics, which are measurable in the response of the resonator. In this experiment, we measured the second-order piezoelectric coefficient of aluminum nitride to be $-(23.1\pm14.1)\times10^{-22}\ \mathrm{m/V^2}$.

physics.app-ph↗

Optical Wireless Information Transfer with Nonlinear Micromechanical Resonators

Wireless transfer of information is the basis of modern communication. It includes cellular, WiFi, Bluetooth and GPS systems, all of which use electromagnetic radio waves with frequencies ranging from typically 100 MHz to a few GHz. However, several long-standing challenges with standard radio-wave wireless transmission still exist, including keeping secure transmission of data from potential compromise. Here, we demonstrate wireless information transfer using a line-of-sight optical architecture with a micromechanical element. In this fundamentally new approach, a laser beam encoded with information impinges on a nonlinear micromechanical resonator located a distance from the laser. The force generated by the radiation pressure of the laser light on the nonlinear micromechanical resonator produces a sideband modulation signal, which carries the precise information encoded in the subtle changes in the radiation pressure. Using this, we demonstrate data and image transfer with one hundred percent fidelity with a single 96 micron by 270 micron silicon resonator element in an optical frequency band. This mechanical approach relies only on the momentum of the incident photons and is therefore able to use any portion of the optical frequency banda band that is 10,000 times wider than the radio frequency band. Our line-of-sight architecture using highly scalable micromechanical resonators offers new possibilities in wireless communication. Due to their small size, these resonators can be easily arrayed while maintaining a small form factor to provide redundancy and parallelism.

physics.app-ph↗

Micromechanical microphone using sideband modulation of nonlinear resonators

We report the successful detection of an audio signal via sideband modulation of a nonlinear piezoelectric micromechanical resonator. The 270$\times$96-$μ$m resonator was shown to be reliable in audio detection for sound intensity levels as low as ambient room noise and to have an unamplified sensitivity of 23.9 $μ$V/Pa. Such an approach may be adapted in acoustic sensors and microphones for consumer electronics or medical equipment such as hearing aids.

physics.app-ph↗

Wireless transfer of power by a 35-GHz metamaterial split-ring resonator rectenna

Wireless transfer of power via high frequency microwave radiation using a miniature split ring resonator rectenna is reported. RF power is converted into DC power by integrating a rectification circuit with the split ring resonator. The near-field behavior of the rectenna is investigated with microwave radiation in the frequency range between 20-40 GHz with a maximum power level of 17 dBm. The observed resonance peaks match those predicted by simulation. Polarization studies show the expected maximum in signal when the electric field is polarized along the edge of the split ring resonator with the gap and minimum for perpendicular orientation. The efficiency of the rectenna is on the order of 1% for a frequency of 37.2 GHz. By using a cascading array of 9 split ring resonators the output power was increased by a factor of 20.

physics.ins-det↗

Perspective: Melanoma diagnosis and monitoring: Sunrise for melanoma therapy but early detection remains in the shade

Melanoma is one of the most dangerous forms of cancer. The five-year survival rate is 98% if it is detected early. However, this rate plummets to 63% for regional disease and 17% when tumors have metastasized, that is, spread to distant sites. Furthermore, the incidence of melanoma has been rising by about 3% per year, whereas the incidence of cancers that are more common is decreasing. A handful of targeted therapies have recently become available that have finally shown real promise for treatment, but for reasons that remain unclear only a fraction of patients respond long term. These drugs often increase survival by only a few months in metastatic patient groups before relapse occurs. More effective treatment may be possible if a diagnosis can be made when the tumor burden is still low. Here, an overview of the current state-of-the-art is provided along with an argument for newer technologies towards early point-of-care diagnosis of melanoma.

q-bio.TO↗

Nanomechanical detection of the spin Hall effect

The spin Hall effect creates a spin current in response to a charge current in a material that has strong spin-orbit coupling. The size of the spin Hall effect in many materials is disputed, requiring independent measurements of the effect. We develop a novel mechanical method to measure the size of the spin Hall effect, relying on the equivalence between spin and angular momentum. The spin current carries angular momentum, so the flow of angular momentum will result in a mechanical torque on the material. We determine the size and geometry of this torque and demonstrate that it can be measured using a nanomechanical device. Our results show that measurement of the spin Hall effect in this manner is possible and also opens possibilities for actuating nanomechanical systems with spin currents.

cond-mat.mes-hall↗

Field Effect Transistor Nanosensor for Breast Cancer Diagnostics

Silicon nanochannel field effect transistor (FET) biosensors are one of the most promising technologies in the development of highly sensitive and label-free analyte detection for cancer diagnostics. With their exceptional electrical properties and small dimensions, silicon nanochannels are ideally suited for extraordinarily high sensitivity. In fact, the high surface-to-volume ratios of these systems make single molecule detection possible. Further, FET biosensors offer the benefits of high speed, low cost, and high yield manufacturing, without sacrificing the sensitivity typical for traditional optical methods in diagnostics. Top down manufacturing methods leverage advantages in Complementary Metal Oxide Semiconductor (CMOS) technologies, making richly multiplexed sensor arrays a reality. Here, we discuss the fabrication and use of silicon nanochannel FET devices as biosensors for breast cancer diagnosis and monitoring.

q-bio.QM↗

Detection of the melanoma biomarker TROY using silicon nanowire field-effect transistors

Antibody-functionalized silicon nanowire field-effect transistors have been shown to exhibit excellent analyte detection sensitivity enabling sensing of analyte concentrations at levels not readily accessible by other methods. One example where accurate measurement of small concentrations is necessary is detection of serum biomarkers, such as the recently discovered tumor necrosis factor receptor superfamily member TROY (TNFRSF19), which may serve as a biomarker for melanoma. TROY is normally only present in brain but it is aberrantly expressed in primary and metastatic melanoma cells and shed into the surrounding environment. In this study, we show the detection of different concentrations of TROY in buffer solution using top-down fabricated silicon nanowires. We demonstrate the selectivity of our sensors by comparing the signal with that obtained from bovine serum albumin in buffer solution. Both the signal size and the reaction kinetics serve to distinguish the two signals. Using a fast-mixing two-compartment reaction model, we are able to extract the association and dissociation rate constants for the reaction of TROY with the antibody immobilized on the sensor surface.

q-bio.QM↗

Noise color and asymmetry in stochastic resonance with silicon nanomechanical resonators

Stochastic resonance with white noise has been well established as a potential signal amplification mechanism in nanomechanical two-state systems. While white noise represents the archetypal stimulus for stochastic resonance, typical operating environments for nanomechanical devices often contain different classes of noise, particularly colored noise with a 1/f spectrum. As a result, improved understanding of the effects of noise color will be helpful in maximizing device performance. Here we report measurements of stochastic resonance in a silicon nanomechanical resonator using 1/f noise and Ornstein-Uhlenbeck noise types. Power spectral densities and residence time distributions provide insight into asymmetry of the bistable amplitude states, and the data sets suggest that 1/f^alpha noise spectra with increasing noise color (i.e. alpha) may lead to increasing asymmetry in the system, reducing the achievable amplification. Furthermore, we explore the effects of correlation time tau on stochastic resonance with the use of exponentially correlated noise. We find monotonic suppression of the spectral amplification as the correlation time increases.

cond-mat.mes-hall↗

Electrostatically actuated silicon-based nanomechanical switch at room temperature

We demonstrate a silicon-based high frequency nanomechanical device capable of switching controllably between two states at room temperature. The device uses a nanomechanical resonator with two distinct states in the hysteretic nonlinear regime. In contrast to prior work, we demonstrate room temperature electrostatic actuation and sensing of the switching device with 100% fidelity by phase modulating the drive signal. This phase-modulated device can be used as a low-power high-speed mechanical switch integrated on-chip with silicon circuitry.

cond-mat.mes-hall↗

Nanomechanical Detection of Itinerant Electron Spin Flip

Spin is an intrinsically quantum property, characterized by angular momentum. A change in the spin state is equivalent to a change in the angular momentum or mechanical torque. This spin-induced torque has been invoked as the intrinsic mechanism in experiments ranging from the measurements of angular momentum of photons g-factor of metals and magnetic resonance to the magnetization reversal in magnetic multi-layers A spin-polarized current introduced into a nonmagnetic nanowire produces a torque associated with the itinerant electron spin flip. Here, we report direct measurement of this mechanical torque and itinerant electron spin polarization in an integrated nanoscale torsion oscillator, which could yield new information on the itinerancy of the d-band electrons. The unprecedented torque sensitivity of 10^{-22} N m/ \sqrt{Hz} may enable applications for spintronics, precision measurements of CP-violating forces, untwisting of DNA and torque generating molecules.

cond-mat.mes-hall↗

Evidence of universality in the dynamical response of micromechanical diamond resonators at millikelvin temperatures

We report kelvin to millikelvin-temperature measurements of dissipation and frequency shift in megahertz-range resonators fabricated from ultra-nanocrystalline diamond. Frequency shift $δf/f_0$ and dissipation $Q^{-1}$ demonstrate temperature dependence in the millikelvin range similar to that predicted by the glass model of tunneling two level systems. The logarithmic temperature dependence of $δf/ f_0$ is in good agreement with such models, which include phonon relaxation and phonon resonant absorption. Dissipation shows a weak power law, $Q^{-1}\propto T^{1/3}$, followed by saturation at low temperature. A comparison of both the scaled frequency shift and dissipation in equivalent micromechanical structures made of single-crystal silicon and gallium arsenide indicates universality in the dynamical response.

cond-mat.mes-hall↗

Surface modified silicon nanochannel for urea sensing

Silicon nanowires have been surface functionalized with the enzyme urease for biosensor applications to detect and quantify urea concentration. The device is nanofabricated from a silicon on insulator (SOI) wafer with a top down lithography approach. The differential conductance of silicon nanowires can be tuned for optimum performance using the source drain bias voltage, and is sensitive to urea at low concentration. The experimental results show a linear relationship between surface potential change and urea concentration in the range of 0.1 to 0.68 mM. The sensitivity of our devices shows high reproducibility with time and different measurement conditions. The nanowire urea biosensor offers the possibility of high quality, reusable enzyme sensor array integration with silicon based circuits.

physics.bio-ph↗

Measurement of Aharonov-Bohm oscillations in mesoscopic metallic rings in the presence of high-frequency electromagnetic fields

We report measurements of Aharonov-Bohm oscillations in normal metal rings in the presence of high frequency electromagnetic fields. The power dependence of the decoherence time scale tau_phi(P) agrees well with the anticipated power law tau_phi proportional to P^(-1/5) when the field-induced decoherence rate tau_ac^(-1) is large compared to the intrinsic decoherence rate tau_o^(-1), measured in the absence of external fields. As theoretically expected, we observe a decline in field-induced decoherence when tau_ac^(-1)<=tau_o^(-1). The frequency dependence of tau_phi shows a minimum in the oscillation amplitude at a characteristic frequency, omega_(ac)=1/tau_(o), where tau_(o) is evaluated from the oscillation amplitude using the standard mesoscopic theory. Both the suppression in the oscillation amplitude and the concomitant change in conductivity allow a direct measurement of the intrinsic decoherence time scale.

cond-mat.mes-hall↗

Quantum Nanomechanics

Quantum Nanomechanics is the emerging field which pertains to the mechanical behavior of nanoscale systems in the quantum domain. Unlike the conventional studies of vibration of molecules and phonons in solids, quantum nanomechanics is defined as the quantum behavior of the entire mechanical structure, including all of its constituents--the atoms, the molecules, the ions, the electrons as well as other excitations. The relevant degrees of freedom of the system are described by macroscopic variables and quantum mechanics in these variables is the essential aspect of quantum nanomechanics. In spite of its obvious importance, however, quantum nanomechanics still awaits proper and complete physical realization. In this article, I provide a conceptual framework for defining quantum nanomechanical systems and their characteristic behaviors, and chart out possible avenues for the experimental realization of bona fide quantum nanomechanical systems.

cond-mat.mes-hall↗

Channel-Width Dependent Enhancement in Nanoscale Field Effect Transistor

We report the observation of channel-width dependent enhancement in nanoscale field effect transistors containing lithographically-patterned silicon nanowires as the conduction channel. These devices behave as conventional metal-oxide-semiconductor field-effect transistors in reverse source drain bias. Reduction of nanowire width below 200 nm leads to dramatic change in the threshold voltage. Due to increased surface-to-volume ratio, these devices show higher transconductance per unit width at smaller width. Our devices with nanoscale channel width demonstrate extreme sensitivity to surface field profile, and therefore can be used as logic elements in computation and as ultrasensitive sensors of surface-charge in chemical and biological species.

cond-mat.other↗

Nanoscale field effect transistor for biomolecular signal amplification

We report amplification of biomolecular recognition signal in lithographically defined silicon nanochannel devices. The devices are configured as field effect transistors (FET) in the reversed source-drain bias region. The measurement of the differential conductance of the nanowire channels in the FET allows sensitive detection of changes in the surface potential due to biomolecular binding. Narrower silicon channels demonstrate higher sensitivity to binding due to increased surface-to-volume ratio. The operation of the device in the negative source-drain region demonstrates signal amplification. The equivalence between protein binding and change in the surface potential is described.

physics.bio-ph↗