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arXiv · 0910.0567

Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for in vivo Cancer Therapy

Zhuang Liu·Alice C. Fan·Kavya Rakhra·Sarah Sherlock·Andrew Goodwin·Xiaoyuan Chen·Qiwei Yang·Dean W. Felsher·Hongjie Dai
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Abstract

Many therapeutic advantages such as prolonged circulation in the blood, increased tumor drug uptake, enhanced therapeutic efficacy, and markedly reduced toxic side effects are provided by a carbon nanotube based chemotherapeutic formulation. In this system, doxorubicin (DOX) is loaded onto the sidewalls of functionalized single-walled carbon nanotubes by supramolecular pi-pi stacking.

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Zhuang Liu, Alice C. Fan, Kavya Rakhra, Sarah Sherlock, Andrew Goodwin, Xiaoyuan Chen, Qiwei Yang, Dean W. Felsher, Hongjie Dai. 2009-10-03. Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for in vivo Cancer Therapy. https://arxiv.org/abs/0910.0567

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