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arXiv · 1409.4139

A feasible roadmap for developing volumetric probability atlas of localized prostate cancer

Liang Zhao·Jianhua Xuan·Yue Wang
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Abstract

A statistical volumetric model, showing the probability map of localized prostate cancer within the host anatomical structure, has been developed from 90 optically-imaged surgical specimens. This master model permits an accurate characterization of prostate cancer distribution patterns and an atlas-informed biopsy sampling strategy. The model is constructed by mapping individual prostate models onto a site model, together with localized tumors. An accurate multi-object non-rigid warping scheme is developed based on a mixture of principal-axis registrations. We report our evaluation and pilot studies on the effectiveness of the method and its application to optimizing needle biopsy strategies.

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Liang Zhao, Jianhua Xuan, Yue Wang. 2014-09-15. A feasible roadmap for developing volumetric probability atlas of localized prostate cancer. https://arxiv.org/abs/1409.4139

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