On the kinetics that moves Myosin V

Christian Maes; Winny O'Kelly de Galway

doi:10.1016/j.physa.2015.05.071

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arXiv · 1412.6689

On the kinetics that moves Myosin V

Christian Maes·Winny O'Kelly de Galway

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Abstract

Molecular motor proteins such as Myosin V, Dynein or Kinesin are no ratchets, at least not with a flashing asymmetric potential; the crucial asymmetry is in the dynamical activity. We make that explicit in terms of a simple Markov model, emphasizing the kinetic (and non-thermodynamic) aspects of stochastic transport. The analysis shows the presence of a fluctuation symmetry in that part of the dynamical activity which is antisymmetric under reversal of trailing and leading head of the motor. The direction of the motor motion is determined by it.

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Christian Maes, Winny O'Kelly de Galway. 2014-12-20. On the kinetics that moves Myosin V. https://doi.org/10.1016/j.physa.2015.05.071

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