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arXiv · 1504.06463

The dichotomy structure of Y chromosome Haplogroup N

Kang Hu·Shi Yan·Kai Liu·Chao Ning·Lan-Hai Wei·Shi-Lin Li·Bing Song·Ge Yu·Feng Chen·Li-Jun Liu·Zhi-Peng Zhao·Chuan-Chao Wang·Ya-Jun Yang·Zhen-Dong Qin·Jing-Ze Tan·Fu-Zhong Xue·Hui Li·Long-Li Kang·Li Jin
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Abstract

Haplogroup N-M231 of human Y chromosome is a common clade from Eastern Asia to Northern Europe, being one of the most frequent haplogroups in Altaic and Uralic-speaking populations. Using newly discovered bi-allelic markers from high-throughput DNA sequencing, we largely improved the phylogeny of Haplogroup N, in which 16 subclades could be identified by 33 SNPs. More than 400 males belonging to Haplogroup N in 34 populations in China were successfully genotyped, and populations in Northern Asia and Eastern Europe were also compared together. We found that all the N samples were typed as inside either clade N1-F1206 (including former N1a-M128, N1b-P43 and N1c-M46 clades), most of which were found in Altaic, Uralic, Russian and Chinese-speaking populations, or N2-F2930, common in Tibeto-Burman and Chinese-speaking populations. Our detailed results suggest that Haplogroup N developed in the region of China since the final stage of late Paleolithic Era.

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Kang Hu, Shi Yan, Kai Liu, Chao Ning, Lan-Hai Wei, Shi-Lin Li, Bing Song, Ge Yu, Feng Chen, Li-Jun Liu, Zhi-Peng Zhao, Chuan-Chao Wang, Ya-Jun Yang, Zhen-Dong Qin, Jing-Ze Tan, Fu-Zhong Xue, Hui Li, Long-Li Kang, Li Jin. 2015-04-24. The dichotomy structure of Y chromosome Haplogroup N. https://arxiv.org/abs/1504.06463

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