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arXiv · 1705.04998

Transport or Store? Synthesizing Flow-based Microfluidic Biochips using Distributed Channel Storage

Chunfeng Liu·Bing Li·Hailong Yao·Paul Pop·Tsung-Yi Ho·Ulf Schlichtmann
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Abstract

Flow-based microfluidic biochips have attracted much atten- tion in the EDA community due to their miniaturized size and execution efficiency. Previous research, however, still follows the traditional computing model with a dedicated storage unit, which actually becomes a bottleneck of the performance of bio- chips. In this paper, we propose the first architectural synthe- sis framework considering distributed storage constructed tem- porarily from transportation channels to cache fluid samples. Since distributed storage can be accessed more efficiently than a dedicated storage unit and channels can switch between the roles of transportation and storage easily, biochips with this dis- tributed computing architecture can achieve a higher execution efficiency even with fewer resources. Experimental results con- firm that the execution efficiency of a bioassay can be improved by up to 28% while the number of valves in the biochip can be reduced effectively.

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Chunfeng Liu, Bing Li, Hailong Yao, Paul Pop, Tsung-Yi Ho, Ulf Schlichtmann. 2017-05-14. Transport or Store? Synthesizing Flow-based Microfluidic Biochips using Distributed Channel Storage. https://arxiv.org/abs/1705.04998

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