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arXiv · 1803.04554

Reconstruction Algorithm Design for Mitigating the Orientation Dependent Conspicuity of Fiber-Like signals in Digital Breast Tomosynthesis

Sean D. Rose·Ingrid Reiser·Emil Y. Sidky·Xiaochuan Pan
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Abstract

There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Cooper's ligaments, blood vessels, and spiculated lesions. Such structures can exhibit orientation dependent variations in conspicuity. This study demonstrates the presence of in-plane orientation-dependent signal conspicuity for fiber-like signals in DBT and shows how reconstruction algorithm design can mitigate this phenomenon. We uncover a tradeoff between minimizing orientation-dependence and preserving depth resolution that is dictated by the regularization strength employed in reconstruction.

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Sean D. Rose, Ingrid Reiser, Emil Y. Sidky, Xiaochuan Pan. 2018-03-12. Reconstruction Algorithm Design for Mitigating the Orientation Dependent Conspicuity of Fiber-Like signals in Digital Breast Tomosynthesis. https://arxiv.org/abs/1803.04554

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