arXiv · 1904.03127
Deep Learning Under the Microscope: Improving the Interpretability of Medical Imaging Neural Networks
Abstract
In this paper, we propose a novel interpretation method tailored to histological Whole Slide Image (WSI) processing. A Deep Neural Network (DNN), inspired by Bag-of-Features models is equipped with a Multiple Instance Learning (MIL) branch and trained with weak supervision for WSI classification. MIL avoids label ambiguity and enhances our model's expressive power without guiding its attention. We utilize a fine-grained logit heatmap of the models activations to interpret its decision-making process. The proposed method is quantitatively and qualitatively evaluated on two challenging histology datasets, outperforming a variety of baselines. In addition, two expert pathologists were consulted regarding the interpretability provided by our method and acknowledged its potential for integration into several clinical applications.
Explore related subjects
Keep this discovery
Magdalini Paschali, Muhammad Ferjad Naeem, Walter Simson, Katja Steiger, Martin Mollenhauer, Nassir Navab. 2019-04-05. Deep Learning Under the Microscope: Improving the Interpretability of Medical Imaging Neural Networks. https://arxiv.org/abs/1904.03127
Cite the original work for its findings. Save a collection to share your selection of sources.