Temperature induced tunable particle separation

Aleksandra Słapik; Jerzy Łuczka; Jakub Spiechowicz

Home/Archive/arXiv

arXiv · 1910.08808

Temperature induced tunable particle separation

Aleksandra Słapik·Jerzy Łuczka·Jakub Spiechowicz

View original source ↗Read source document ↗Export metadata ↓

Abstract

An effective approach to isolation of sub-micro sized particles is desired to separate cancer and healthy cells or in therapy of Parkinson's and Alzheimer's disease. However, since bioparticles span a large size range comprising several orders of magnitude, development of an adequate separation method is a challenging task. We consider a collection of non-interacting Brownian particles of various sizes moving in a symmetric periodic potential and subjected to an external unbiased harmonic driving as well as a constant bias. We reveal a nonintuitive, yet efficient, separation mechanism based on thermal fluctuations induced negative mobility phenomenon in which particles of a given size move in a direction opposite to the applied bias. By changing solely temperature of the system one can separate particles of various strictly defined sizes. This novel approach may be important step towards development of point-of-care lab-on-a-chip devices.

Explore related subjects

cond-mat.stat-mech cond-mat.mes-hall cond-mat.soft physics.chem-ph

Keep this discovery

BibTeX RIS

Aleksandra Słapik, Jerzy Łuczka, Jakub Spiechowicz. 2019-10-19. Temperature induced tunable particle separation. https://arxiv.org/abs/1910.08808

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Universal sampling of spin systems across quenched disorder

Statistical physics extracts macroscopic laws by averaging over the many microscopic degrees of freedom of a system. Disordered systems demand a second and far harder average, one over the quenched randomness itself. The classic analytical routes, the replica and cavity methods, become uncontrolled outside mean-field or tree-like limits, and conventional numerical algorithms like parallel tempering require expensive, independent equilibration for every disorder realization. In this work, we introduce a universal neural variational framework that amortizes inference across the disorder ensemble, eliminating both the need for per-instance Markov chain equilibration and the cost of retraining instance-specific variational ansatzes. Built on an encoder-decoder Transformer architecture, after training once, it produces an explicit approximation to the Boltzmann distribution given previously unseen disorder realizations without further optimization. We validate this framework on 2D Edwards-Anderson models, and apply it to the random-bond Ising model, successfully capturing the Binder cumulant crossings near the Nishimori multicritical point. These results shift the object of variational inference from the single instance to the disorder ensemble, opening a route to frustrated many-body systems where instance-by-instance computation is prohibitive.

cond-mat.stat-mech↗

arXiv2026

Information-Theoretic Characterization of Macroscopic Chaos Emerging from the Chemical Master Equation

Open chemical reaction networks exhibit stochastic concentration dynamics at finite system sizes, whereas their macroscopic limit is governed by deterministic rate equations that can display chaos. In this Letter, we show theoretically that a rate of information loss constructed from two-time mutual information recovers the Kolmogorov-Sinai entropy in the deterministic limit. We verify this result through numerical simulations of a Markov jump process for a three-species system involving seven reactions.

cond-mat.stat-mech↗

arXiv2026

Orientational order on non-orientable domains

We study the statistical properties of passive and active many-body systems with orientational degrees of freedom on non-orientable domains. By rephrasing topological constraints as non-local symmetry relations on an orientable double-cover, we show that non-orientability eliminates global rotational soft modes without acting like an external field. In a passive XY model, this results in topological caging, where orientational fluctuations that exhibit conventional diffusive behavior on a torus saturate on a Klein bottle to a finite value that we compute exactly in the thermodynamic limit. In models of active self-propelled particles with orientational degrees of freedom, topological caging persists despite continuously changing interaction neighborhoods. In an active Ising spin model, non-orientability enforces the coexistence of ordered anti-parallel domains with vanishing global polar order, a state that is absent on orientable domains.

cond-mat.stat-mech↗