arXiv · 2005.02689
Dynamic brain spectrum acquired by a real-time ultra-spectral imaging chip with reconfigurable metasurfaces
Abstract
Spectral imaging paves way for various fields and particular in biomedical research. However, spectral imaging mainly depending on spatial or temporal scanning, cannot achieve high temporal, spatial and spectral resolution simultaneously. In this study, we demonstrated a silicon real-time ultra-spectral imaging chip based on reconfigurable metasurfaces, comprising of 155,216 (356$\times$436) image-adaptive micro-spectrometers with ultra-high center-wavelength accuracy of 0.04 nm and spectral resolution of 0.8 nm. It is employed for imaging brain hemodynamics, and the dynamic spectral absorption properties of deoxyhemoglobin and oxyhemoglobin in a rat barrel cortex were obtained, which enlighten the spectroscopy in vivo studies and other real-time applications.
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Jian Xiong, Xusheng Cai, Kaiyu Cui, Yidong Huang, Jiawei Yang, Hongbo Zhu, Wenzheng Li, Bo Hong, Shijie Rao, Zekun Zheng, Sheng Xu, Yuhan He, Fang Liu, Xue Feng, Wei Zhang. 2020-05-06. Dynamic brain spectrum acquired by a real-time ultra-spectral imaging chip with reconfigurable metasurfaces. https://doi.org/10.1364/optica.440013
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