SearcharxivSearch

arXiv · 2008.02469

Design, Development and Comparison of two Different Measurements Devices for Time-Resolved Determination of Phase Shifts of Bioimpedances

Abstract

Bioimpedance measurements are a non-invasive method to determine the composition of organic tissue. For measuring the complex bioimpedance between two electrodes, an alternating current with a constant amplitude is injected into the tissue. The developed voltage drop is used to calculate the real and imaginary part of the impedance under test. Measurements in the past indicated that it could be possible that the beating of the heart has an effect on the measured phase shift of the impedance under test. In this work a hardware system is developed, capable of measuring changes of the bioimpedance phase shift with high resolution. Two different measurement methods are used. The first method is an analog circuit, which has been developed in a previous project. The other method uses the integrated circuit AFE4300 (Texas Instruments) [1]. The results of both methods are transmitted with a microcontroller (Xmega256A3BU from Atmel Corp.) via the USB interface to a host PC. On the host PC the visualization of the measurements and the control of the embedded system is achieved with a developed LabView program. The work includes the development of the hardware and software, as well as a comparison of the accuracy of the two measurement methods. The result of a verification of the systems is that both measurement methods have an effective resolution of about 0.3{\deg}.

Explore related subjects

Keep this discovery

BibTeXRIS

Roman Kusche, Steffen Kaufmann, Martin Ryschka. 2020-08-06. Design, Development and Comparison of two Different Measurements Devices for Time-Resolved Determination of Phase Shifts of Bioimpedances. https://arxiv.org/abs/2008.02469

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

High-Speed Semi-FE Readout Module for ATLAS MDT at HL-LHC: Design and Production-Level Characterization

The High-Luminosity upgrade of the Large Hadron Collider (HL-LHC) introduces increased demands on the ATLAS Muon Spectrometer, particularly in terms of data throughput, timing distribution and system reliability. The Phase-II Chamber Service Module (CSM) is a key component of the upgraded Monitored Drift Tube (MDT) trigger and readout system, providing a high-speed interface between the front-end electronics and the backend systems. This paper describes the design and implementation of the Phase-II CSM, together with its validation. The results show that the CSM supports two independent optical uplinks, each operating at a line rate of 10.24 Gbps, together with clock distribution and slow control in the expected operating environment. Integration with small-diameter MDT (sMDT) chambers and tests with the prototype L0MDT trigger system are also presented. The CSM boards are now in production and will be used for installation and integration during the upcoming LHC Long Shutdown.

physics.ins-det

Spectral Discrimination of Deposited Gamma-Ray Energies in a Simulated CeBr$_3$ Scintillator

We show that wavelength measurements of individual detected optical photons may provide additional information about gamma-ray energy deposited in a CeBr$_3$ crystal when the detected-photon-count distributions overlap for nearby gamma-ray energies. Monoenergetic 662 and 629 keV gammas are used in a Geant4 simulation of a $25\times25\times20~\mathrm{mm^3}$ CeBr$_3$ crystal. Assuming a light yield of $6.0\times10^4$ photons/MeV, a wavelength-independent photon-detection efficiency of 30%, and a wavelength resolution of $\sigma_{\lambda}=40$ nm, we find that the fraction of photons reconstructed above 385 nm gives an event-level separation of $\sim$ 2 standard deviations between the 662 and 629 keV event populations selected within the same $\sim$ 1%-wide detected-photon-count interval. No timing or reconstructed interaction-position information is used. The result demonstrates, within the present simulation model, that event-dependent optical spectra can retain energy information beyond an undifferentiated photon count.

physics.ins-det

Operation of a negative ion gas time projection chamber without electronegative fill gases

The high fidelity reconstruction of particle tracks in micropatterned gaseous time projection chambers renders this technology ideal for future rare-event searches, including direction-sensitive dark matter experiments. Large drift distances are typically required for such experiments, so that the overall spatial resolution is limited by diffusion. Negative ion drift exhibits lower diffusion than electron drift and is thus an attractive option for realising a large-scale detector. The use of electronegative gases to create negative ions introduces technical challenges, most notably a reduction in gain when compared to conventional gas mixtures. In this study, we demonstrate a new method for negative ion generation via dissociative electron attachment using the conventional molecular fill gas CF$_4$. Our optical measurements of negative ion drift indicate electron attachment lengths of $<$1 mm and comparable gain to electron avalanches. The individual negative ion avalanches were also time-resolved, allowing the number of ions reaching the readout to be counted. We measure an improved energy resolution by single ion counting, relative to an integrated electron avalanche signal measured under identical gain conditions.

physics.ins-det