arXiv · 2011.13867
Fluctuating diffusivity of RNA-protein particles: Analogy with thermodynamics
Abstract
A formal analogy of fluctuating diffusivity to thermodynamics is discussed for messenger RNA molecules fluorescently fused to a protein in living cells. Regarding the average value of the fluctuating diffusivity of such RNA-protein particles as the analog of the internal energy, the analogs of the quantity of heat and work are identified. The Clausius-like inequality is shown to hold for the entropy associated with diffusivity fluctuations, which plays a role analogous to the thermodynamic entropy, and the analog of the quantity of heat. The change of the statistical fluctuation distribution is also examined from a geometric perspective. The present discussions may contribute to a deeper understanding of the fluctuating diffusivity in view of the laws of thermodynamics.
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Yuichi Itto. 2020-11-27. Fluctuating diffusivity of RNA-protein particles: Analogy with thermodynamics. https://doi.org/10.3390/e23030333
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