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arXiv · 2101.03006

Absence of enhanced uptake of fluorescent magnetic particles into human liver cells in a strong magnetic field gradient

Leon Abelmann·Eunheui Gwag·Baeckkyoung Sung
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Abstract

We investigated whether we can detect enhanced magnetic nanoparticle uptake under application of a large magnetic force by tagging the particles with a fluorescent dye. Human liver cells were cultured in a micro-channel slide and exposed to two types of magnetic nanoparticles with a diameter of 100 nm at a concentration of 10000 particles/cell for 24 hours. Even though we achieved a magnetic force that exceeded the gravitational force by a factor of 25, we did not observe a statistically significant increase of immobilised particles per cell.

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Leon Abelmann, Eunheui Gwag, Baeckkyoung Sung. 2021-01-08. Absence of enhanced uptake of fluorescent magnetic particles into human liver cells in a strong magnetic field gradient. https://arxiv.org/abs/2101.03006

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