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Baeckkyoung Sung

Publications and source records attributed to Baeckkyoung Sung.

4 recordsLinked to original sources

Electronics-free, ultra-low-power, wearable sensor chip for high-frequency electromagnetic field detection

High-frequency electromagnetic fields (EMFs) are increasingly recognized either as environmental risk factors or as tools for electromagnetic attacks, which are difficult to detect in situ. Existing high-frequency EMF sensors face significant limitations related to structural simplicity, integration with mobile technology, and low energy consumption. To address these challenges, we propose a novel sensor concept based on a magnetically hybridized liquid crystal (LC) microdevice. The hybrid LC chip is designed to exhibit an optical response to external radio-frequency fields without the need for electronic components or an external power supply, relying solely on ambient light. Both sides of the chip are covered with polymer-based crossed polarizer films. The chip is filled with flexible matrices containing thermotropic LCs, such as the rod-like 4-cyano-4'-pentylbiphenyl, into which a network of thin ferromagnetic wires is embedded. The resulting field-responsive LC microdisplay operates via a simple magnetothermal mechanism, and its optical response is sufficiently strong to be visible to the naked eye.

physics.app-ph↗

Permanent magnet systems to study the interaction between magnetic nanoparticles and cells in microslide channels

We optimized designs of permanent magnet systems to study the effect of magnetic nanoparticles on cell cultures in microslide channels. This produced two designs, one of which is based on a large cylindrical magnet that applies a uniform force density of 6 MN/m$^3$ on soft magnetic iron-oxide spherical nanoparticles at a field strength of over 300 mT. We achieved a force uniformity of better than 14% over the channel area leading to a concentration variation that was below our measurement resolution. The second design was aimed at maximizing the force by using a Halbach array. We indeed increased the force by more than one order of magnitude at force density values over 400 MN/m$^3$, but at the cost of uniformity. However, the latter system can be used to trap magnetic nanoparticles efficiently and to create concentration gradients. We demonstrated both designs by analyzing the effect of magnetic forces on the cell viability of human hepatoma HepG2 cells in the presence of bare Fe$_2$O$_3$ and cross-linked dextran iron-oxide cluster-type particles (MicroMod). Python scripts for magnetic force calculations and particle trajectory modeling as well as source files for 3D prints have been made available so these designs can be easily adapted and optimized for other geometries.

physics.bio-ph↗

Absence of enhanced uptake of fluorescent magnetic particles into human liver cells in a strong magnetic field gradient

We investigated whether we can detect enhanced magnetic nanoparticle uptake under application of a large magnetic force by tagging the particles with a fluorescent dye. Human liver cells were cultured in a micro-channel slide and exposed to two types of magnetic nanoparticles with a diameter of 100 nm at a concentration of 10000 particles/cell for 24 hours. Even though we achieved a magnetic force that exceeded the gravitational force by a factor of 25, we did not observe a statistically significant increase of immobilised particles per cell.

physics.bio-ph↗

Depletion-driven Morphological Transitions in Hexagonal Crystallites of Virus Rods

The assembly of nanometer-sized building blocks into complex morphologies is not only of fundamental interest but also plays a key role in material science and nanotechnology. We show that the shape of self-assembled superstructures formed by rod-like viruses can be controlled by tuning the attraction via the depletion interaction between the rods. Using nonadsorbing polymers as a depleting agent, we demonstrate that a hierarchical unidimensional self-organization into crystalline clusters emerges progressively upon increasing depletion attraction -and enhanced growth kinetics. We observe a polymorphic change proceeding from two-dimensional (2D) crystalline monolayers at weak depletion to one-dimensional (1D) columnar fibers at strong depletion, via the formation of smectic fibrils at intermediate depletion strength. A simple theory for reversible polymerization enables us to determine the typical bond energy between monomeric units making up the smectic fibrils. We also demonstrate that gentle flow-assistance can be used to template filament-like structures into highly aligned supported films. Our results showcase a generic bottom-up approach for tuning the morphology of crystalline superstructures through modification of the interaction between non-spherical building blocks. This provides a convenient pathway for controlling self-organization, dimensionality and structure-formation of anisotropic nanoparticles for use in nanotechnology and functional materials.

cond-mat.soft↗