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arXiv · 2101.11709

A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy

J. P. J. Chen·K. E. Schmidt·J. C. H. Spence·R. A. Kirian
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Abstract

We develop an algorithm capable of imaging a three-dimensional object given a collection of two-dimensional images of that object that are significantly influenced by the curvature of the Ewald sphere. These two-dimensional images cannot be approximated as projections of the object. Such an algorithm is useful in cryo-electron microscopy where larger samples, higher resolution, or lower energy electron beams are desired, all of which contribute to the significance of Ewald curvature.

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J. P. J. Chen, K. E. Schmidt, J. C. H. Spence, R. A. Kirian. 2021-02-07. A new solution to the curved Ewald sphere problem for 3D image reconstruction in electron microscopy. https://doi.org/10.1016/j.ultramic.2021.113234

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