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arXiv · 2107.12006

Thermodynamics and SARS-CoV-2: neurological effects in post-Covid 19 syndrome

Umberto Lucia·Giulia Grisolia·Thomas S. Deisboeck
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Abstract

There is increasing evidence that infection with SARS-CoV-2 can cause a spectrum of neurological symptoms. In this paper, we develop a theoretical concept underlying such neurological COVID-19 consequences by employing a non-equilibrium thermodynamic approach that allows linking the neuronal electric potential with a virus-induced pH variation. Our theoretical findings support further experimental work on therapeutically correcting electrolyte imbalances, such as Na$^+$ and K$^+$, to attenuate the neurological effects of SARS-CoV-2.

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Umberto Lucia, Giulia Grisolia, Thomas S. Deisboeck. 2021-07-26. Thermodynamics and SARS-CoV-2: neurological effects in post-Covid 19 syndrome. https://doi.org/10.1478/aapp.992a3

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