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arXiv · 2307.16690

Model predictive control for the prescription of antithyroid agents

Maylin Menzel·Tobias M. Wolff·Johannes W. Dietrich·Matthias A. Müller
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Abstract

Although hyperthyroidism is a common disease, the pharmaceutical therapy is based on a trial-and-error approach. We extend a mathematical model of the pituitary-thyroid feedback loop such that the intake of one antithyroid agent, namely methimazole (MMI), can be considered and use a model predictive control (MPC) scheme to determine suitable dosages.

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Maylin Menzel, Tobias M. Wolff, Johannes W. Dietrich, Matthias A. Müller. 2023-07-31. Model predictive control for the prescription of antithyroid agents. https://arxiv.org/abs/2307.16690

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