Dynamics of a nonlinear infection viral propagation model with one fixed boundary and one free boundary

Abstract

In this paper we study a nonlinear infection viral propagation model with diffusion, in which, the left boundary is fixed and with homogeneous Dirichlet boundary conditions, while the right boundary is free. We find that the habitat always expands to the half line $[0, \infty)$, and that the virus and infected cells always die out when the {\it Basic Reproduction Number} $\mathcal{R}_0\le 1$, while the virus and infected cells have persistence properties when $\mathcal{R}_0>1$. To obtain the persistence properties of virus and infected cells when $\mathcal{R}_0>1$, the most work of this paper focuses on the existence and uniqueness of positive equilibrium solutions for subsystems and the existence of positive equilibrium solutions for the entire system.