Transformer-Based Inverse Microrheology for Experimental Mechanics at Ultra-High Strain Rates

Abstract

Traditional rheological tools are often limited in characterizing soft materials under ultra-high strain-rate loading conditions (> 1000 s^-1) due to constraints in spatiotemporal resolution, loading rate, and invasiveness. Recently, inertial microcavitation rheometry (IMR), which utilizes laser-induced inertial cavitation (LIC) to dynamically deform surrounding materials, has emerged as a powerful experimental mechanics technique for probing nonlinear viscoelastic properties under extreme loading conditions. However, conventional IMR relies on computationally expensive iterative inverse fitting procedures, limiting its scalability and real-time applicability. Here, we introduce a new AI-enhanced experimental mechanics framework, called Bubble Dynamics Transformer (BDT), that integrates physics-based cavitation simulations with Transformer neural network architectures to achieve rapid inverse characterization of soft material viscoelasticity from experimentally measured bubble dynamics. The proposed framework directly predicts viscoelastic material parameters from time-resolved bubble radius evolution curves without iterative optimization. The BDT is trained using synthetic datasets generated from physics-based Keller--Miksis cavitation simulations and validated using experimental laser-induced cavitation data obtained from hydrogels and viscous polymer solutions. The proposed AI-driven framework demonstrates excellent agreement with our previous IMR while substantially accelerating constitutive parameter inference. Experimental demonstrations further reveal the capability of the framework to characterize rate-dependent material behavior across a wide range of soft materials, from viscous liquids to various viscoelastic hydrogels, at ultra-high strain rates.