LabOS: The AI-XR Co-Scientist That Sees and Works With Humans

Le Cong; David Smerkous; Xiaotong Wang; Di Yin; Zaixi Zhang; Ruofan Jin; Yinkai Wang; Michal Gerasimiuk; Ravi K. Dinesh; Alex Smerkous; Lihan Shi; Joy Zheng; Ian Lam; Xuekun Wu; Shilong Liu; Peishan Li; Yi Zhu; Ning Zhao; Meenal Parakh; Simran Serrao; Imran A. Mohammad; Chao-Yeh Chen; Xiufeng Xie; Tiffany Chen; David Weinstein; Greg Barbone; Belgin Caglar; John B. Sunwoo; Fuxin Li; Jia Deng; Joseph C. Wu; Sanfeng Wu; Mengdi Wang

arXiv · 2510.14861

LabOS: The AI-XR Co-Scientist That Sees and Works With Humans

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Abstract

Modern science advances fastest when thought meets action. LabOS represents the first AI co-scientist that unites computational reasoning with physical experimentation through multimodal perception, self-evolving agents, and Extended-Reality(XR)-enabled human-AI collaboration. By connecting multi-model AI agents, smart glasses, and robots, LabOS allows AI to see what scientists see, understand experimental context, and assist in real-time execution. Across applications -- from cancer immunotherapy target discovery to stem-cell engineering and material science -- LabOS shows that AI can move beyond computational design to participation, turning the laboratory into an intelligent, collaborative environment where human and machine discovery evolve together.

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Le Cong, David Smerkous, Xiaotong Wang, Di Yin, Zaixi Zhang, Ruofan Jin, Yinkai Wang, Michal Gerasimiuk, Ravi K. Dinesh, Alex Smerkous, Lihan Shi, Joy Zheng, Ian Lam, Xuekun Wu, Shilong Liu, Peishan Li, Yi Zhu, Ning Zhao, Meenal Parakh, Simran Serrao, Imran A. Mohammad, Chao-Yeh Chen, Xiufeng Xie, Tiffany Chen, David Weinstein, Greg Barbone, Belgin Caglar, John B. Sunwoo, Fuxin Li, Jia Deng, Joseph C. Wu, Sanfeng Wu, Mengdi Wang. 2025-10-16. LabOS: The AI-XR Co-Scientist That Sees and Works With Humans. https://arxiv.org/abs/2510.14861

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