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The Study of Correlation Structures of DNA Sequences: A Critical Review

Wentian Li
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Abstract

The study of correlation structure in the primary sequences of DNA is reviewed. The issues reviewed include: symmetries among 16 base-base correlation functions, accurate estimation of correlation measures, the relationship between $1/f$ and Lorentzian spectra, heterogeneity in DNA sequences, different modeling strategies of the correlation structure of DNA sequences, the difference of correlation structure between coding and non-coding regions (besides the period-3 pattern), and source of broad distribution of domain sizes. Although some of the results remain controversial, a body of work on this topic constitutes a good starting point for future studies.

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Wentian Li. 1997-04-09. The Study of Correlation Structures of DNA Sequences: A Critical Review. https://doi.org/10.1016/s0097-8485(97)00022-3

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