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Unzipping DNA : A hypothesis on correlation during replication

Somendra M. Bhattacharjee
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Abstract

Based on the result of an unzipping phase transition by a force in a model of DNA, we hypothesize that the DnaA-type proteins act as a pulling agent with a force slightly less than the critical force for unzipping. The dynamic (space-time) correlation of unzipping then drives the subsequent events of replication. In such a correlation driven scenario, there is no need of a replisome as a structural unit and this elusive replisome may not exist at all.

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Somendra M. Bhattacharjee. 2000-11-13. Unzipping DNA : A hypothesis on correlation during replication. https://arxiv.org/abs/cond-mat/0010132

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