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Real time noninvasive cancer diagnostics

Z. V. Jaliashvili·T. D. Medoidze·Z. G. Melikishvili·K. M. Mardaleishvili·J. J. Ramsden
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Abstract

Laser illumination of tissue results in a characteristic fluorescence emission spectrum whose features depend on the type of tissue, viz., healthy, adenoma or malignant. Hence measurement of the fluorescence is potentially a rapid and reliable diagnostic method. We have applied the technique to thyroid tissues and found that judicious normalization of the fluorescence spectrum reveals a close correlation between spectral shape and tissue type. Hence the pathological state of the tissue can be unambiguously identified from the laser-induced fluorescence spectrum. The method is rapid and portable and is therefore eminently suitable for use during operations.

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Z. V. Jaliashvili, T. D. Medoidze, Z. G. Melikishvili, K. M. Mardaleishvili, J. J. Ramsden. 2005-02-20. Real time noninvasive cancer diagnostics. https://arxiv.org/abs/physics/0502102

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