arXiv subjects

Alessandro Salatiello

Publications and source records attributed to Alessandro Salatiello.

11 recordsLinked to original sources

arXiv2026

When Large Language Models are More PersuasiveThan Incentivized Humans, and Why

Large Language Models (LLMs) have been shown to be highly persuasive, but when and why they outperform humans is still an open question. We compare the persuasiveness of two LLMs (Claude 3.5 Sonnet and DeepSeek v3) against humans who had incentives to persuade, using an interactive, real-time conversational setting. We demonstrate that LLMs persuasive superiority is context-dependent: it depends on whether the persuasion attempt is truthful (towards the right answer) or deceptive (towards the wrong answer) and on the LLM model, and wanes over repeated interactions (unlike human persuasiveness). In our first large-scale experiment, humans vs LLMs (Claude 3.5 Sonnet) interacted with other humans who were completing an online quiz for a reward, attempting to persuade them toward a given (either correct or incorrect) answer. Claude was more persuasive than incentivized human persuaders both in truthful and deceptive contexts and it significantly increased accuracy if persuasion was truthful, but decreased it if persuasion was deceptive. In a follow-up experiment with Deepseek v3, we replicated the findings about accuracy but found greater LLM persuasiveness only if the persuasion was deceptive. Linguistic analyses of the persuaders texts suggest that these effects may be due to LLMs expressing higher conviction than humans.

cs.CL↗

arXiv2026

Neural mechanisms of predictive processing: a collaborative community experiment through the OpenScope program

This review synthesizes advances in predictive processing within the sensory cortex. Predictive processing theorizes that the brain continuously predicts sensory inputs, refining neuronal responses by highlighting prediction errors. We identify key computational primitives, such as stimulus adaptation, dendritic computation, excitatory/inhibitory balance and hierarchical processing, as central to this framework. Our review highlights convergences, such as top-down inputs and inhibitory interneurons shaping mismatch signals, and divergences, including species-specific hierarchies and modality-dependent layer roles. To address these conflicts, we propose experiments in mice and primates using in-vivo two-photon imaging and electrophysiological recordings to test whether temporal, motor, and omission mismatch stimuli engage shared or distinct mechanisms. The resulting dataset, collected and shared via the OpenScope program, will enable model validation and community analysis, fostering iterative refinement and refutability to decode the neural circuits of predictive processing.

q-bio.NC↗

arXiv2026

From Modules to Movement: Deconstructing the Modular Architecture of the Motor System

Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback, slow actuators, and strict energetic constraints. A central question is what organizational principles underlie this efficiency. One widely recognized principle of neural organization is modularity, which enables complex problems to be decomposed into simpler subproblems that specialized modules are optimized to solve. In this review, we argue that modularity is a fundamental organizing principle of the motor system. We first summarize evidence for brain modularity, ranging from classical lesion studies to contemporary graph-theoretical analyses. We next discuss the main factors underlying the emergence and evolutionary selection of modular architectures, highlighting the computational advantages they provide. We then review the major neuroanatomical modules that structure current descriptions of the motor system and compare three prominent computational frameworks of motor control$-$optimal feedback control theory, muscle synergy theory, and dynamical systems approaches$-$showing that all implicitly or explicitly rely on specialized computational modules. We conclude by contrasting the key strengths and limitations of existing frameworks and by proposing promising directions toward more comprehensive theories.

q-bio.NC↗

arXiv2026

Modularity is the Bedrock of Natural and Artificial Intelligence

The remarkable performance of modern AI systems has been driven by unprecedented scales of data, computation, and energy -- far exceeding the resources required by human intelligence. This disparity highlights the need for new guiding principles and motivates drawing inspiration from the fundamental organizational principles of brain computation. Among these principles, modularity has been shown to be critical for supporting the efficient learning and strong generalization abilities consistently exhibited by humans. Furthermore, modularity aligns well with the No Free Lunch Theorem, which highlights the need for problem-specific inductive biases and motivates architectures composed of specialized components that solve subproblems. However, despite its fundamental role in natural intelligence and its demonstrated benefits across a range of seemingly disparate AI subfields, modularity remains relatively underappreciated in mainstream AI research. In this work, we review several research threads in artificial intelligence and neuroscience through a conceptual framework that highlights the central role of modularity in supporting both artificial and natural intelligence. In particular, we examine what computational advantages modularity provides, how it has emerged as a solution across several AI research areas, which modularity principles the brain exploits, and how modularity can help bridge the gap between natural and artificial intelligence.

cs.AI↗

arXiv2025

Hierarchical Time Series Forecasting Via Latent Mean Encoding

Coherently forecasting the behaviour of a target variable across both coarse and fine temporal scales is crucial for profit-optimized decision-making in several business applications, and remains an open research problem in temporal hierarchical forecasting. Here, we propose a new hierarchical architecture that tackles this problem by leveraging modules that specialize in forecasting the different temporal aggregation levels of interest. The architecture, which learns to encode the average behaviour of the target variable within its hidden layers, makes accurate and coherent forecasts across the target temporal hierarchies. We validate our architecture on the challenging, real-world M5 dataset and show that it outperforms established methods, such as the TSMixer model.

cs.LG↗

arXiv2024

TopoX: A Suite of Python Packages for Machine Learning on Topological Domains

We introduce TopoX, a Python software suite that provides reliable and user-friendly building blocks for computing and machine learning on topological domains that extend graphs: hypergraphs, simplicial, cellular, path and combinatorial complexes. TopoX consists of three packages: TopoNetX facilitates constructing and computing on these domains, including working with nodes, edges and higher-order cells; TopoEmbedX provides methods to embed topological domains into vector spaces, akin to popular graph-based embedding algorithms such as node2vec; TopoModelX is built on top of PyTorch and offers a comprehensive toolbox of higher-order message passing functions for neural networks on topological domains. The extensively documented and unit-tested source code of TopoX is available under MIT license at https://pyt-team.github.io/}{https://pyt-team.github.io/.

cs.LG↗

arXiv2024

Large language models surpass human experts in predicting neuroscience results

Scientific discoveries often hinge on synthesizing decades of research, a task that potentially outstrips human information processing capacities. Large language models (LLMs) offer a solution. LLMs trained on the vast scientific literature could potentially integrate noisy yet interrelated findings to forecast novel results better than human experts. To evaluate this possibility, we created BrainBench, a forward-looking benchmark for predicting neuroscience results. We find that LLMs surpass experts in predicting experimental outcomes. BrainGPT, an LLM we tuned on the neuroscience literature, performed better yet. Like human experts, when LLMs were confident in their predictions, they were more likely to be correct, which presages a future where humans and LLMs team together to make discoveries. Our approach is not neuroscience-specific and is transferable to other knowledge-intensive endeavors.

q-bio.NC↗

arXiv2024

ICML Topological Deep Learning Challenge 2024: Beyond the Graph Domain

This paper describes the 2nd edition of the ICML Topological Deep Learning Challenge that was hosted within the ICML 2024 ELLIS Workshop on Geometry-grounded Representation Learning and Generative Modeling (GRaM). The challenge focused on the problem of representing data in different discrete topological domains in order to bridge the gap between Topological Deep Learning (TDL) and other types of structured datasets (e.g. point clouds, graphs). Specifically, participants were asked to design and implement topological liftings, i.e. mappings between different data structures and topological domains --like hypergraphs, or simplicial/cell/combinatorial complexes. The challenge received 52 submissions satisfying all the requirements. This paper introduces the main scope of the challenge, and summarizes the main results and findings.

cs.LG↗

arXiv2024

ICML 2023 Topological Deep Learning Challenge : Design and Results

This paper presents the computational challenge on topological deep learning that was hosted within the ICML 2023 Workshop on Topology and Geometry in Machine Learning. The competition asked participants to provide open-source implementations of topological neural networks from the literature by contributing to the python packages TopoNetX (data processing) and TopoModelX (deep learning). The challenge attracted twenty-eight qualifying submissions in its two-month duration. This paper describes the design of the challenge and summarizes its main findings.

cs.LG↗

arXiv2021

Continuous Decoding of Daily-Life Hand Movements from Forearm Muscle Activity for Enhanced Myoelectric Control of Hand Prostheses

State-of-the-art motorized hand prostheses are endowed with actuators able to provide independent and proportional control of as many as six degrees of freedom (DOFs). The control signals are derived from residual electromyographic (EMG) activity, recorded concurrently from relevant forearm muscles. Nevertheless, the functional mapping between forearm EMG activity and hand kinematics is only known with limited accuracy. Therefore, no robust method exists for the reliable computation of control signals for the independent and proportional actuation of more than two DOFs. A common approach to deal with this limitation is to pre-program the prostheses for the execution of a restricted number of behaviors (e.g., pinching, grasping, and wrist rotation) that are activated by the detection of specific EMG activation patterns. However, this approach severely limits the range of activities users can perform with the prostheses during their daily living. In this work, we introduce a novel method, based on a long short-term memory (LSTM) network, to continuously map forearm EMG activity onto hand kinematics. Critically, unlike previous work, which often focuses on simple and highly controlled motor tasks, we tested our method on a dataset of activities of daily living (ADLs): the KIN-MUS UJI dataset. To the best of our knowledge, ours is the first reported work on the prediction of hand kinematics that uses this challenging dataset. Remarkably, we show that our network is able to generalize to novel untrained ADLs. Our results suggest that the presented method is suitable for the generation of control signals for the independent and proportional actuation of the multiple DOFs of state-of-the-art hand prostheses.

cs.RO↗

arXiv2020

Recurrent Neural Network Learning of Performance and Intrinsic Population Dynamics from Sparse Neural Data

Recurrent Neural Networks (RNNs) are popular models of brain function. The typical training strategy is to adjust their input-output behavior so that it matches that of the biological circuit of interest. Even though this strategy ensures that the biological and artificial networks perform the same computational task, it does not guarantee that their internal activity dynamics match. This suggests that the trained RNNs might end up performing the task employing a different internal computational mechanism, which would make them a suboptimal model of the biological circuit. In this work, we introduce a novel training strategy that allows learning not only the input-output behavior of an RNN but also its internal network dynamics, based on sparse neural recordings. We test the proposed method by training an RNN to simultaneously reproduce internal dynamics and output signals of a physiologically-inspired neural model. Specifically, this model generates the multiphasic muscle-like activity patterns typically observed during the execution of reaching movements, based on the oscillatory activation patterns concurrently observed in the motor cortex. Remarkably, we show that the reproduction of the internal dynamics is successful even when the training algorithm relies on the activities of a small subset of neurons sampled from the biological network. Furthermore, we show that training the RNNs with this method significantly improves their generalization performance. Overall, our results suggest that the proposed method is suitable for building powerful functional RNN models, which automatically capture important computational properties of the biological circuit of interest from sparse neural recordings.

q-bio.NC↗