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Bo Liu

Publications and source records attributed to Bo Liu.

At least 73 records · Page 4Linked to original sources

One Framework for All: Cross-Modal Membership Inference for Generative Models

Large generative models across text-to-text, text-to-image, and image-to-text modalities have been shown to pose significant privacy risks. One fundamental threat is membership inference attacks (MIA), which aim to determine whether a given data point was used in a model's training set. Although prior work has investigated MIAs against these three classes of generative models, existing approaches treat them in isolation and are not cross-applicable, thereby limiting their real-world utility. To address this limitation, we present the first comprehensive study of a unified membership inference framework that applies across text-to-text, text-to-image, and image-to-text modalities. Our approach is grounded in a key modality-agnostic observation: the output distribution of a generative model can approximate its training data distribution. Leveraging this property, we model the distributions of model-generated outputs and auxiliary non-member samples in a shared embedding space, and perform membership inference via likelihood ratio testing. We conduct extensive experiments in a strict black-box setting under both partial-knowledge and zero-knowledge threat models, and evaluate membership inference against both fine-tuning and pre-training data. Experimental results demonstrate our approach's superior performance in comparison to existing state-of-the-art methods, which are typically optimized for a single model class.

cs.LG↗

EndoUFM: Utilizing Foundation Models for Monocular depth estimation of endoscopic images

Depth estimation is a foundational component for 3D reconstruction in minimally invasive endoscopic surgeries. However, existing monocular depth estimation techniques often exhibit limited performance to the varying illumination and complex textures of the surgical environment. While applying foundation models offers a promising approach to enhance the depth estimation performance, the domain gap between the natural images used for pre-training and the target endoscopic images leads to significant semantic perception deficiencies. In this study, EndoUFM is introduced as an unsupervised monocular depth estimation framework that innovatively \underline{U}tilizes dual Foundation Models for Endoscopic images, thereby enhancing the depth estimation performance by leveraging the powerful pre-learned priors. The framework features a novel adaptive fine-tuning strategy that incorporates Random Vector Low-Rank Adaptation (RVLoRA) to enhance model adaptability, and a Residual block based on Depthwise Separable Convolution (Res-DSC) to improve the capture of fine-grained local features. A mask-guided smoothness loss is also introduced to enforce depth consistency within anatomical structures. Extensive experiments on the SCARED, Hamlyn, SERV-CT, and EndoNeRF datasets confirm that our method achieves state-of-the-art performance while maintaining an efficient model size. This work contributes to augmenting surgeons' spatial perception during minimally invasive procedures, thereby enhancing surgical precision and safety, with crucial implications for augmented reality and navigation systems. Our code is available at https://github.com/RealMindyY/EndoUFM.

cs.CV↗

ECGFlowCMR: Pretraining with ECG-Generated Cine CMR Helps Cardiac Disease Classification and Phenotype Prediction

Cardiac Magnetic Resonance (CMR) imaging provides a comprehensive assessment of cardiac structure and function but remains constrained by high acquisition costs and reliance on expert annotations, limiting the availability of large-scale labeled datasets. In contrast, electrocardiograms (ECGs) are inexpensive, widely accessible, and offer a promising modality for conditioning the generative synthesis of cine CMR. To this end, we propose ECGFlowCMR, a novel ECG-to-CMR generative framework that integrates a Phase-Aware Masked Autoencoder (PA-MAE) and an Anatomy-Motion Disentangled Flow (AMDF) to address two fundamental challenges: (1) the cross-modal temporal mismatch between multi-beat ECG recordings and single-cycle CMR sequences, and (2) the anatomical observability gap due to the limited structural information inherent in ECGs. Extensive experiments on the UK Biobank and a proprietary clinical dataset demonstrate that ECGFlowCMR can generate realistic cine CMR sequences from ECG inputs, enabling scalable pretraining and improving performance on downstream cardiac disease classification and phenotype prediction tasks.

eess.IV↗

Human and AI collaboration for pulmonary nodule segmentation

Medical expert annotators are scarce, and blind reliance on artificial intelligence (AI) can be misleading, motivating approaches in which humans, particularly junior medical trainees or even non-medical personnel, collaborate with AI to achieve robust medical segmentation. Although the Segment Anything Model (SAM) shows promise for general-purpose image segmentation, its performance in human-AI collaboration for specialized medical tasks has not been thoroughly evaluated. Here we present Hi-Seg, a human-in-the-loop segmentation framework for pulmonary nodules built on SAM. Humans iteratively refine prompts through trial-and-error learning and semantic reasoning, progressively guiding SAM toward higher-quality masks. Using chest CT scans from 1,179 patients across 12 centers, we conducted the first large-scale external validation of collaborative human-SAM segmentation. Across all annotator groups, Hi-Seg achieved a mean Dice score of almost 85%, outperforming five state-of-the-art deep learning models by 10-22% and 13 SAM variants by 1-29%. Hi-Seg improved segmentation accuracy while reducing annotation time for medical annotators, and briefly trained non-medical annotators achieved performance comparable to that of the junior medical student. These findings suggest that human-in-the-loop segmentation can reduce clinician workload, enable scalable crowdsourced annotation, and transform clinical workflows by facilitating the safe and efficient integration of foundation models into routine clinical practice.

cs.CV↗

MammoExpert: Benchmarking Chain-of-Thought Reasoning in Mammography Diagnosis

Mammography is an essential tool for breast cancer detection, with millions of examinations conducted annually. However, publicly available high-quality mammography datasets for AI development remain limited in both scale and annotation richness, particularly regarding pathological subtype coverage and structured diagnostic reasoning annotations. In this paper, we present MammoExpert, the first mammography dataset with Chain-of-Thought reasoning annotations across three diagnostic phases: (i) primal observation, (ii) factual assessment, and (iii) diagnostic synthesis. Comprising 2,379 mammography images covering 67 WHO-classified histopathology subtypes, each exam provides 42 radiographic features annotated by nine senior radiologists. We evaluate its performance on the breast lesion classification task, demonstrating superior accuracy and reasonability compared to existing classification models. Combining public dataset CBIS-DDSM with MammoExpert yields 7.1\% classification accuracy improvement, while the training model to learn CoT reasoning achieves another 4\% gain on the MammoExpert test set. Similar improvements are observed on INBreast and Vindr datasets, where the full approach yields accuracy gains of 6.9\% and 6.7\%, respectively. MammoExpert can serve as a benchmark for interpretable breast lesion diagnosis through explicit CoT reasoning.

cs.CV↗

RoboSSM: Scalable In-context Imitation Learning via State-Space Models

In-context imitation learning (ICIL) enables robots to learn tasks from prompts consisting of just a handful of demonstrations. By eliminating the need for parameter updates at deployment time, this paradigm supports few-shot adaptation to novel tasks. However, recent ICIL methods rely on Transformers, which have computational limitations and tend to underperform when handling longer prompts than those seen during training. In this work, we introduce RoboSSM, a scalable recipe for in-context imitation learning based on state-space models (SSM). Specifically, RoboSSM replaces Transformers with Longhorn -- a state-of-the-art SSM that provides linear-time inference and strong extrapolation capabilities, making it well-suited for long-context prompts. Through diverse experiments on the LIBERO benchmark, we demonstrate the effectiveness of applying SSMs to ICIL, achieving improved generalization to both unseen and long-horizon tasks than Transformer-based ICIL methods by handling longer contexts at test-time. These results show for the first time that SSMs are an efficient and scalable backbone for ICIL. Our code is available at https://github.com/youngjuY/RoboSSM.

cs.RO↗

Suppression of p-Wave Altermagnetism by Localized 4f Electrons in CeNiAsO

Altermagnetism, characterized by momentum-dependent spin splitting and zero net magnetization, has so far been explored mainly in weakly or moderately correlated d-electron systems. How symmetry-allowed altermagnetic band splitting manifests in heavy-fermion materials, where magnetic exchange competes with Kondo correlations, remains unclear. Here we use high-resolution angle-resolved photoemission spectroscopy (ARPES) to investigate CeNiAsO, a Kondo-lattice system that was predicted to be a candidate for p-wave altermagnetism. Fermi surface mapping and polarization-dependent ARPES show that the experimentally observed itinerant bands are mainly derived from Ni 3d orbitals, while resonant photoemission reveals that the Ce 4f states remain predominantly localized with residual c-f hybridization. Ultra-low-temperature measurements reveal no resolvable near-Fermi-level p-wave-like exchange splitting on the Ni 3d-derived conduction bands across the successive antiferromagnetic transitions. These experimental observations cannot be captured by an itinerant-4f band-structure description, which predicts a sizable p-wave splitting in the itinerant bands. When the localized Ce 4f character is incorporated, our band structure calculations indicate that the itinerant Ce 4f band weight is shifted away from the Fermi level and the p-wave-like splitting on the Ni 3d-derived bands is reduced to the few-meV scale. These results establish CeNiAsO as a strongly correlated f-electron setting in which the magnetic symmetry allows p-wave-like band splitting, but localized 4f electrons strongly suppress its observable itinerant single-particle signature.

cond-mat.str-el↗

ActWorld: From Explorable to Interactive World Model via Action-Aware Memory

Interactive world models aim to simulate environment dynamics under real-time user actions. However, their action vocabulary is largely confined to navigation: most actions correspond to motion (e.g., walk, turn, look around), while interaction with objects in the scene (e.g., pick up plates, open doors, or trigger physical responses) is either absent, restricted to game domains, or relegated to prompt-to-full-video scenarios. The resulting worlds are visually explorable but not truly actionable. In this work, we present ActWorld, an interactive world model that extends prior navigation-centric generators to support mid-rollout object interaction within a chunk-autoregressive framework. We argue that the navigation-interaction gap stems from two bottlenecks. First, a data bottleneck: the lack of human-object interaction data with accurate, dense labels. Second, a memory bottleneck: recency-biased history compression in existing world models discards the event-transition frames that causally determine subsequent object states, leading to an action-forgetting pathology. On the data side, we construct a 100K interaction video dataset, each annotated with per-chunk captions via chain-of-thought reasoning. On the model side, we introduce a hierarchical action-aware memory design that routes history compression by interaction importance, complemented by a persistent memory bank that maintains event-update and object-identity tokens across long rollouts. Experiments show that ActWorld supports both flexible navigation and rich object interaction within a single model, substantially improving interaction fidelity over navigation-only baselines without sacrificing viewpoint control. Project page is available at https://interactwm.github.io/ActWorld.

cs.CV↗

Auditing Machine Unlearning: A Systematic Research on Whether Models Truly Forget

Machine unlearning has been extensively studied in response to growing privacy concerns and regulatory requirements. However, auditing whether unlearning algorithms have truly erased the influence of specific data remains an open challenge. The lack of reliable and practical auditing mechanisms can lead to critical privacy risks, such as residual information leakage. This paper initiates a systematic investigation into whether existing unlearning algorithms can truly forget the designated data. We propose the first practical and general-purpose auditing framework for machine unlearning, inspired by the concept of proof of ignorance. Our framework addresses the key practicality limitations of existing methods by eliminating the need for retraining-from-scratch baselines, avoiding the training of large numbers of shadow models, and requiring no intrusive intervention in the original training process. To evaluate the effectiveness of our framework, we first conduct validation experiments to verify its soundness and completeness. We then perform comprehensive experiments across six datasets and ten representative unlearning methods. The results demonstrate that our framework reliably distinguishes between successful and failed unlearning. In particular, we observe that retraining-based and fine-tuning-based methods can achieve effective unlearning, even when the target data remain in the original dataset. In contrast, de-optimization-based methods fail to achieve true unlearning and instead degrade the model's performance. Fisher/Hessian-based methods also fail to unlearn requested data, even formal certification is provided. Moreover, we show that our framework is robust against fake unlearning attempts and generalizes well to large language models.

cs.LG↗

Earth Science Foundation Models: From Perception to Reasoning and Discovery

Large foundation models (FMs) are transforming Earth science by integrating heterogeneous multimodal data, such as multi-platform imagery, gridded reanalysis data, diverse geophysical and geochemical observations, and domain-specific text, to support tasks ranging from basic perception to advanced scientific discovery. This paper provides a unified review of Earth science foundation models (Earth FMs) through two complementary dimensions: depth, which traces the evolution of model capabilities from perception to multimodal reasoning and agentic scientific workflows, and breadth, which summarizes their expanding applications across the atmosphere, hydrosphere, lithosphere, biosphere, anthroposphere, and cryosphere, as well as coupled Earth system processes. Using this framework, we review representative multimodal Earth foundation models and compile more than 200 datasets and benchmarks spanning diverse Earth science tasks and modalities. We further discuss key challenges in multimodal data heterogeneity, scientific reliability and continual updating, scalability and sustainability, and the transition from foundation models to agentic and embodied Earth intelligence, and outline future directions toward more integrated, trustworthy, and actionable AI Earth scientists. Overall, this paper offers a structured roadmap for understanding the development of Earth foundation models from both capability depth and application breadth.

astro-ph.IM↗

Agents' Last Exam

Recent AI systems have achieved strong results on a wide range of benchmarks, yet these gains have not translated into economically meaningful deployment across many professional domains. We argue that this gap is largely an evaluation problem: widely used benchmarks lack sustained performance measurement on real and economically valuable workflows. This paper introduces Agents' Last Exam (ALE), a benchmark designed to evaluate AI agents on long horizon, economically valuable, real world tasks with verifiable outcomes. Developed in collaboration with 250+ industry experts, ALE covers non-physical industries defined with reference to O*NET / SOC 2018 (the U.S. federal occupational taxonomy). It is organized around a task taxonomy with 55 sub fields grouped into 13 industry clusters covering 1K+ tasks. Current results show that the hardest tier remains far from saturated: across mainstream harness and backbone configurations, the average full pass rate is below 1%. ALE is designed as a living benchmark: its task pool grows continuously as new workflows and industries are onboarded. More broadly, ALE is intended not merely as another leaderboard, but as an instrument for closing the gap between benchmark success and GDP relevant impact.

cs.AI↗

CausalMoE: A Billion-Scale Multimodal Foundation Model for Granger Causal Discovery with Pattern-Routed Heterogeneous Experts

Granger Causal Discovery (GCD) is fundamental for analyzing temporal dependencies in complex systems. However, existing neural GCD methods predominantly rely on a "one-size-fits-all" paradigm, struggling to capture distribution shifts and dynamic regime changes inherent in real-world time series. This often leads to entangled representations and spurious causal graphs. In this paper, we propose CausalMoE, a billion-scale multimodal Granger causal foundation model that explicitly models patch-level heterogeneity. CausalMoE introduces a Pattern-Routed Mixture of Heterogeneous Experts, which dynamically identifies latent temporal patterns and routes patches to specialized domain experts, effectively decoupling regime-specific mechanisms from shared dynamics. To ensure interpretable graph recovery, we design a Causality-Aware Self-Attention mechanism operating across variables, yielding sparse Granger causal graphs via proximal optimization. Furthermore, CausalMoE is the first to integrate LLMs and VLMs to align numerical signals with textual and visual priors, regularizing causal estimation in complex scenarios. Extensive experiments demonstrate that CausalMoE establishes a new state-of-the-art on fully supervised benchmarks, while effectively generalizing to few-shot settings where traditional methods fail.

cs.LG↗

AnyPPG: An ECG-Guided PPG Foundation Model Trained on Over 100,000 Hours of Recordings for Holistic Health Profiling

Photoplethysmography (PPG) is widely used as a non-invasive and accessible modality for continuous health monitoring. However, despite being a peripheral hemodynamic signal intrinsically coupled with systemic circulation, existing research has largely confined its scope to a narrow range of cardiovascular tasks, leaving a fundamental question underexplored: to what extent can PPG support holistic health profiling beyond traditional cardiovascular applications? To answer this question, we present AnyPPG, a foundation model-based framework designed to reveal the broader health-profiling potential of PPG. To ensure reliable performance for this investigation, AnyPPG is pretrained with ECG guidance on the most diverse PPG corpus with synchronized ECG to date, comprising over 100,000 hours of recordings from six large-scale data sources. This pretraining yields robust and physiologically grounded PPG representations that provide a reliable basis for subsequent analysis. Building upon this pretrained model, we conduct a systematic investigation into the association between PPG and holistic health through, to our knowledge, the first PPG-based phenome-wide disease detection study, spanning 1,468 disease phenotypes in more than 15,000 subjects. Our evaluation demonstrates the effectiveness of AnyPPG: across eight clinical and wearable datasets covering 15 downstream tasks, it achieves the best performance in 13 tasks. More importantly, in the phenome-wide analysis, AnyPPG exhibits meaningful discriminative capability (AUC $\ge$ 0.70) for 307 phenotypes across 16 distinct phecode chapters, including 230 non-circulatory conditions such as dementia and chronic kidney disease, many of which have rarely been explored using PPG. Collectively, these findings indicate that easily acquired PPG signals encode rich health-related information extending well beyond conventional cardiovascular assessment.

eess.SP↗

Improving Adversarial Transferability on Vision-Language Pre-training Models via Surrogate-Specific Bias Correction

Adversarial examples reveal vulnerabilities in Vision-Language Pre-training (VLP) models and provide insights for improving robustness. A key property is cross-model transferability, which enables transfer-based black-box attacks. However, existing attacks often rely heavily on the surrogate model, causing cross-model performance drops. One reason is that adversarial optimization may follow surrogate model responses more than input semantics, making the update direction effective on the surrogate but less transferable to unseen targets. We refer to this dependency as surrogate-specific bias. Motivated by this observation, DeBias-Attack improves transferability by correcting surrogate-specific bias in adversarial optimization directions. It maintains two perturbation branches. The main branch optimizes a perturbation on the original image and obtains the adversarial gradient used to disrupt image-text alignment. The reference branch optimizes a perturbation on a weak-semantic image constructed from the dataset mean image with small Gaussian noise resampled at each iteration. Since this weak-semantic image contains little clear visual content, its optimization reflects surrogate responses more than image semantics, and its reference gradient estimates surrogate-specific bias. DeBias-Attack removes the aligned projection of the main gradient on the reference gradient before updating the adversarial image, then performs context-aware text substitution using the updated adversarial image. DeBias-Attack is the first transfer-based VLP attack that corrects surrogate-specific bias through gradient correction. Experiments show strong performance across VLP models, downstream tasks, and open-source and closed-source multimodal large language models.

cs.CV↗

Hyperon-Nucleon Spectrometer

Chirality lies at the heart of low-energy QCD, governing the symmetry structure that shapes hadron masses and strong interaction dynamics. Among the most compelling open questions tied to chiral dynamics and spontaneous chiral symmetry breaking is the longstanding $Λ$ polarization puzzle, in which $Λ$ hyperons produced in unpolarized hadronic collisions exhibit a surprisingly large transverse polarization that remains theoretically unexplained. This whitepaper presents the proposal for the Hyperon-Nucleon Spectrometer (H-NS) at the High-Intensity heavy-ion Accelerator Facility (HIAF). Leveraging the high energy and high intensity of HIAF's proton and heavy-ion beams, the H-NS experiment will perform systematic studies of hyperon polarization phenomena and their underlying mechanisms in proton-proton ($pp$), proton-nucleus ($pA$), and nucleus-nucleus ($AA$) collisions in the fixed target mode. A wide-range beam energy scan, including proton beams from 3 GeV up to 9.3 GeV (HIAF) and up to 32 GeV (upgraded HIAF), will be conducted to examine the dependence of polarization on collision energy. The spectrometer is designed with specialized detectors capable of high-precision reconstruction of final-state baryon polarizations. Among its many interesting and important measurements, H-NS will simultaneously measure hyperon and proton spin observables to explore the polarization mechanism in hadronic interactions and the spin structure of baryons. Furthermore, the use of $pA$ and $AA$ collisions will enable detailed investigations of cold and hot nuclear matter effects on spin polarization. Its physics program and detector development will significantly benefit the future Electron-ion Collider in China.

physics.ins-det↗

DiBS: Diffusion-Informed Branch Selection

Sudoku is a representative constraint satisfaction problem that requires global structural reasoning under strict discrete constraints. The existing works of solving Sudoku mainly focus on two dominant approaches, i.e., traditional heuristic and deep learning solver. However, they suffer from two complementary limitations: learning-based solvers lack hard correctness guarantees, while complete symbolic solvers are still prone to long-tail search. To address these shortcomings, we propose a novel diffusion model-guided approach, termed as DiBS, for the branch selection search process. Specifically, DiBS keeps the symbolic solver complete and uses the diffusion model as a branch-ordering guide. The core method is ranking candidate values under the current partial assignment and lightweight consistency signal. Furthermore, we provide an in-depth theoretical proof to reveal how it works and why it works. Experiments on the challenging Royle 17-clue Sudoku benchmark show that our DiBS substantially reduces search cost relative to strong heuristic baselines, especially in nodes, backtracks, and long-tail percentiles. Besides, these results confirm that learned global guidance is effective on hard instances where branch-order mistakes are most expensive. All codes are available at https://github.com/shanxierdan/DiBS.

cs.AI↗

Automated Report-Derived Oncology VQA Benchmark for Evaluating Vision-Language Models on 3D Medical Imaging

Evaluating vision-language models (VLMs) on medical images requires benchmarks that are clinically grounded, scalable, and controlled for evaluation confounds. Existing public benchmarks are limited in scale, manually annotated, or potentially leaked into VLM pretraining corpora. We present an automated agent-driven pipeline that generates multiple-choice VQA datasets directly from paired private radiology reports and 3D oncology imaging, producing two complementary question types: RADS-style questions deterministically derived from clinician-defined reporting schemas, and radiology report-derived questions generated by an LLM from radiologist findings and verified against the source report. Applied to four in-house cancer cohorts, the pipeline yields an instance-contamination-controlled benchmark without per-question human annotation. Zero-shot evaluation of six VLMs reveals no dominant model and substantial headroom across all cells. A blind ablation reveals that visual reliance is highly dataset-specific: liver Report-derived questions genuinely require the image, while Lung CT is essentially solvable without it - the leading closed model exceeds its sighted accuracy on Lung CT when blinded - indicating that even private clinical data does not guarantee a contamination-controlled read of visual capability. The pipeline is released as an open agent skill for in-house redeployment.

cs.CV↗

Shortcut to Adiabatic Isomeric Population Transfer of the $^{229}\mathrm{Th}$ Nucleus via Hyperfine Electronic Bridge

The $^{229}$Th nucleus is well known for its exceptionally low-lying nuclear isomeric level, which provides a unique platform for exploring electron-nucleus interactions and gives rise to a variety of rich physical phenomena. One such phenomenon is the hyperfine electronic bridge, which has recently been shown to enable efficient and precise manipulation of the nuclear isomeric levels of $^{229}$Th [W. Wang $et~ al.$, Phys. Rev. Lett. \textbf{133}, 223001 (2024)]. However, that study used the stimulated Raman adiabatic passage method, which requires relatively long operation times. In this work, we employ the stimulated Raman shortcut-to-adiabatic passage method, which dramatically shortens the operation time from the order of hundreds of milliseconds to hundreds of microseconds while maintaining a transfer efficiency of about $79.38\%$.

quant-ph↗