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Christian Baker

Publications and source records attributed to Christian Baker.

4 recordsLinked to original sources

Eversion-based robots can enable safe access,steering and endoscopic imaging within the spinal subarachnoid space

Safe navigation within the spinal subarachnoid space is constrained by its narrow, compliant, and delicate anatomy. Conventional catheters and continuum robots rely on proximal pushing, generating friction and shear along the tissue device interface that limit distal controllability and increase the risk of neural injury. Here, we present a 2 mm diameter eversion-growing robotic platform that enables friction minimised extension and steering within the human spinal subarachnoid space, validated through computational modelling, phantom experiments, and intact human cadaver studies. The robot integrates a miniature endoscope for real time intrathecal visualisation and advances by pressure driven tip eversion, localising motion to the distal tip while minimising translational sliding of the deployed body. Phantom experiments demonstrated reductions of 65.2% in mean interaction force and 48.0% in peak interaction force compared with matched push-based insertion. Physics based modelling showed that eversion based growth redistributed tissue loading, reducing local stress concentrations and interfacial shear relative to conventional insertion. In an intact human cadaver, the system achieved 150 mm of controlled intrathecal extension with concurrent fluoroscopic and endoscopic visualisation, providing access across multiple vertebral levels from a standard lumbar entry point. Postprocedural laminectomy and durotomy revealed no observable macroscopic disruption of the dura mater or surrounding neural structures. These results provide the first mechanically characterised and multimodally validated demonstration of eversion-based robotic navigation in intact human spinal anatomy, establishing a quantitative and procedural foundation for future intrathecal interventions. Further validation in larger anatomical cohorts and under physiological conditions will be required before clinical translation.

cs.RO

Real-time 3D Ultrasonic Needle Tracking with a Photoacoustic Beacon

Many minimally invasive procedures, such as core needle biopsy of focal liver lesions, nerve blocks, and fetal and vascular interventions, are typically performed under ultrasound guidance, which provides real-time, high-resolution visualisation of tissue anatomy. Accurate and efficient localisation of the needle tip relative to patient anatomy is essential for guiding the needle towards the procedure target, avoiding adverse events and reducing the need for repeat procedures. However, the 3D nature of the procedure and poor image contrast of the needle in heterogeneous tissue or at steep insertion angles often lead to confusion over the true location of the tip within the 2D guidance images, and existing methods to enhance needle visibility largely remain limited to 2D. Here, we present a novel interventional ultrasound system capable of 2D B-mode imaging and 3D needle tracking. The tip location is determined from the time-of-flight of ultrasound generated by a photoacoustic beacon embedded in the needle bevel and received by a sparse receiver array distributed around the imaging system's curvilinear ultrasound probe. The measured tracking accuracy was better than 2 mm for depths up to 140 mm in water, and approximately 2 mm on average in an ex vivo tissue phantom, with referenced positions derived from X-ray computed tomography. In a usability study involving 12 clinicians performing biopsy procedures in a ex vivo tissue phantom, the failure rate was reduced by 35%, from 15.8% to 10.3% after only a few minutes of training. These results demonstrate that the proposed system has strong potential to support a wide range of minimally invasive procedures by enabling clinicians to accurately target small anatomical structures, improving the efficiency and effectiveness of diagnostic sampling and therapeutic delivery or ablation, and reducing the risk of adverse events.

physics.med-ph

Volumetric ultrasound imaging with a sparse matrix array and integrated fiber-optic sensing for robust needle tracking in interventional procedures

Accurate visualization of interventional devices, such as medical needles, is essential for the safe and effective guidance of minimally invasive procedures. Ultrasound (US) imaging is widely used for needle guidance, but the two-dimensional nature of most clinical probes limits accurate three-dimensional (3D) localization, particularly of the needle tip. We present a novel system that integrates volumetric US imaging with 3D needle tracking by combining a fiber-optic hydrophone embedded in the needle and a sparse spiral US array. Real-time volumetric imaging was achieved using plane-wave techniques, while precise needle tip tracking was enabled through communication between the probe and hydrophone. The feasibility of the approach was demonstrated using a nerve block training phantom. This proof-of-concept system enables simultaneous volumetric anatomical imaging and 3D needle tip tracking, with strong potential to enhance the efficacy and safety of image-guided interventional procedures.

physics.med-ph

Ultrathin, high-speed, all-optical photoacoustic endomicroscopy probe for guiding minimally invasive surgery

Photoacoustic (PA) endoscopy has shown significant potential for clinical diagnosis and surgical guidance. Multimode fibres (MMFs) are becoming increasing attractive for the development of miniature endoscopy probes owing to ultrathin size, low cost and diffraction-limited spatial resolution enabled by wavefront shaping. However, current MMF-based PA endomicroscopy probes are either limited by a bulky ultrasound detector or a low imaging speed which hindered their usability. In this work, we report the development of a highly miniaturised and high-speed PA endomicroscopy probe that is integrated within the cannula of a 20 gauge medical needle. This probe comprises a MMF for delivering the PA excitation light and a single-mode optical fibre with a plano-concave microresonator for ultrasound detection. Wavefront shaping with a digital micromirror device enabled rapid raster-scanning of a focused light spot at the distal end of the MMF for tissue interrogation. High-resolution PA imaging of mouse red blood cells covering an area 100 microns in diameter was achieved with the needle probe at ~3 frames per second. Mosaicing imaging was performed after fibre characterisation by translating the needle probe to enlarge the field-of-view in real-time. The developed ultrathin PA endomicroscopy probe is promising for guiding minimally invasive surgery by providing functional, molecular and microstructural information of tissue in real-time.

physics.med-ph