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Craig M. Lancaster

Publications and source records attributed to Craig M. Lancaster.

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Characteristics of a 9 MeV electron beam for total skin electron radiotherapy evaluated in comparison to a 6 MeV electron beam

Characteristics of a 9 MeV electron beam were investigated, to evaluate potential benefits for patients with extensive mycosis fungoides lesions that are deeper than commonly treated with 6 MeV total skin electron therapy (TSET or TSE/TSEI/TSEB/TSEBT). A comprehensive commissioning measurement program was completed for TSET delivery using high-dose-rate 6 MeV and 9 MeV electron beams from a Varian TrueBeam linac. Various phantoms and dosimeters were set up 300 cm from isocenter, behind a 6 mm PMMA spoiler screen, and used for optimising beam-pair gantry angles, measuring depth-dose, lateral and horizontal profiles and B-factors, as well as performing end-to-end tests. The key clinical distinctions observed for the 9 MeV TSET beam pair compared to the 6 MeV TSET beam pair were that the 80% dose depth increased to nearly 1 cm and the practical range increased to 3.5 cm, while the maximum dose remained within 0.2 cm of the surface. Vertical and horizontal dose profiles measured with the two energies were almost indistinguishable. The 9 MeV TSET beam has been shown to achieve greater depth penetration compared to the commonly used 6 MeV TSET beam, without detrimentally affecting the dose uniformity achievable in the patient plane. TSET treatments with 9 MeV electrons may be advisable for patients with extensive lesions that are too deep for effective treatment with a 6 MeV beam.

physics.med-ph

Measuring foetal dose from tomotherapy treatments

Introduction: Treating pregnant women in the radiotherapy clinic is a rare occurrence. When it does occur, it is vital that the dose received by the developing embryo or foetus is understood as fully as possible. This study presents the first investigation of foetal doses delivered during helical tomotherapy treatments. Materials & Methods: Six treatment plans were delivered to an anthropomorphic phantom using a tomotherapy machine. These included treatments of the brain, unilateral and bilateral head-and-neck, chest wall, and upper lung. Measurements of foetal dose were made with an ionisation chamber positioned at various locations longitudinally within the phantom to simulate a variety of patient anatomies. Results: All measurements were below the established limit of 100 mGy for a high risk of damage during the first trimester. The largest dose encountered was 75 mGy (0.125% of prescription dose). The majority of treatments with measurement positions less than 30 cm fell into the range of uncertain risk (50 - 100 mGy). All treatments with measurement positions beyond 30 cm fell into the low risk category (< 50 mGy). Conclusions: For the cases in this study, tomotherapy resulted in foetal doses that are at least on par with, if not significantly lower than, similar 3D conformal or intensity-modulated treatments delivered with other devices. Recommendations were also provided for estimating foetal doses from tomotherapy plans.

physics.med-ph