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arXiv · 2606.21312

Characteristics of a 9 MeV electron beam for total skin electron radiotherapy evaluated in comparison to a 6 MeV electron beam

Tanya Kairn·Craig M. Lancaster·Scott B. Crowe
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Abstract

Characteristics of a 9 MeV electron beam were investigated, to evaluate potential benefits for patients with extensive mycosis fungoides lesions that are deeper than commonly treated with 6 MeV total skin electron therapy (TSET or TSE/TSEI/TSEB/TSEBT). A comprehensive commissioning measurement program was completed for TSET delivery using high-dose-rate 6 MeV and 9 MeV electron beams from a Varian TrueBeam linac. Various phantoms and dosimeters were set up 300 cm from isocenter, behind a 6 mm PMMA spoiler screen, and used for optimising beam-pair gantry angles, measuring depth-dose, lateral and horizontal profiles and B-factors, as well as performing end-to-end tests. The key clinical distinctions observed for the 9 MeV TSET beam pair compared to the 6 MeV TSET beam pair were that the 80% dose depth increased to nearly 1 cm and the practical range increased to 3.5 cm, while the maximum dose remained within 0.2 cm of the surface. Vertical and horizontal dose profiles measured with the two energies were almost indistinguishable. The 9 MeV TSET beam has been shown to achieve greater depth penetration compared to the commonly used 6 MeV TSET beam, without detrimentally affecting the dose uniformity achievable in the patient plane. TSET treatments with 9 MeV electrons may be advisable for patients with extensive lesions that are too deep for effective treatment with a 6 MeV beam.

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Tanya Kairn, Craig M. Lancaster, Scott B. Crowe. 2026-06-19. Characteristics of a 9 MeV electron beam for total skin electron radiotherapy evaluated in comparison to a 6 MeV electron beam. https://arxiv.org/abs/2606.21312

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