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Daguang Xu

Publications and source records attributed to Daguang Xu.

At least 19 recordsLinked to original sources

From Articulated Kinematics to Routed Visual Control for Action-Conditioned Surgical Video Generation

Action-conditioned surgical video generation is a critical yet highly challenging problem for robotic surgery. The core difficulty is that low-dimensional control vectors must precisely govern complex image-space evolution. In this work, we propose a kinematic-to-visual lifting paradigm that converts articulated kinematics into a unified set of five image-aligned control modalities. Building on this representation, we introduce a hierarchically routed visual control framework that selectively activates the most relevant control modalities and motion scales. Instead of uniformly applying all control signals, our model performs hierarchical routing to dynamically allocate conditioning capacity. We further design kinematic-prior-guided routing loss functions to ensure physically meaningful, temporally stable, and efficient expert utilization. To improve efficiency, we propose a budgeted training and inference scheme that leverages routing-induced sparsity. By selectively discarding low-significance control pathways during training and execution, our approach enables adaptive computation that is complementary to standard distillation. We additionally construct a new benchmark with curated articulated annotations, obtained through human-in-the-loop semantic labeling and differentiable pose tracking, providing realistic supervision for action-conditioned surgical video generation. Extensive experiments demonstrate that our method consistently improves action faithfulness, visual fidelity, and cross-domain generalization over diverse baselines. Moreover, our efficient variant achieves substantial reductions in latency while maintaining strong control accuracy.

cs.CV

BaT: Towards Self-Evolving Medical Research Agent with Stage Rubrics

Long-horizon agents are beginning to automate complete workflows that produce code, reports, and research artifacts. Medical imaging workflows are multi-stage and data-sensitive, while expert trajectories remain scarce and difficult to share. Structured benchmarks can localize failures through stage-level rubrics, but standard post-training discards these diagnostics before the next training round. We present Benchmark-as-Teacher (BaT), a recursive self-improvement system for agent post-training. BaT contains two linked components: the asynchronous Stage Bank data pipeline and BiCuRL (Bilevel Curriculum Reinforcement Learning), its self-improving post-training method. Stage Bank synthesizes content-isolated training states outside the policy-update loop. BiCuRL uses a fixed held-out evaluation to select the next stage curriculum, verifies rollouts with task rubrics, updates the policy with GRPO, and returns the candidate checkpoint to evaluation. On AutoMedBench-Lite, BaT-4B and BaT-9B more than double the Overall scores of their Qwen Instruct baselines. BaT-9B Agent reaches 79.6 Overall, exceeding Claude Opus 4.6 with Claude Code at 77.5.

cs.AI

Latent Interpolation Learning Using Diffusion Models for Cardiac Volume Reconstruction

Cardiac Magnetic Resonance (CMR) imaging is a critical tool for diagnosing and managing cardiovascular disease, yet its utility is often limited by the sparse acquisition of 2D short-axis slices, resulting in incomplete volumetric information. Accurate 3D reconstruction from these sparse slices is essential for comprehensive cardiac assessment, but existing methods face challenges, including reliance on predefined interpolation schemes (e.g., linear or spherical), computational inefficiency, and dependence on additional semantic inputs such as segmentation labels or motion data. To address these limitations, we propose a novel Cardiac Latent Interpolation Diffusion (CaLID) framework that introduces three key innovations. First, we present a data-driven interpolation scheme based on diffusion models, which can capture complex, non-linear relationships between sparse slices and improves reconstruction accuracy. Second, we design a computationally efficient method that operates in the latent space and speeds up 3D whole-heart upsampling time by a factor of 24, reducing computational overhead compared to previous methods. Third, with only sparse 2D CMR images as input, our method achieves SOTA performance against baseline methods, eliminating the need for auxiliary input such as morphological guidance, thus simplifying workflows. We further extend our method to 2D+T data, enabling the effective modeling of spatiotemporal dynamics and ensuring temporal coherence. Extensive volumetric evaluations and downstream segmentation tasks demonstrate that CaLID achieves superior reconstruction quality and efficiency. By addressing the fundamental limitations of existing approaches, our framework advances the state of the art for spatio and spatiotemporal whole-heart reconstruction, offering a robust and clinically practical solution for cardiovascular imaging.

eess.IV

Token-Based Affordance Grounding with Large Vision-Language Models

Affordance grounding aims to localize image regions that support a specific action, serving as a core capability for physical intelligence and embodied perception. Previous studies have primarily relied on weakly supervised learning with action labels from exocentric images. However, these methods often struggle with visually ambiguous exocentric images containing co-occurring actions; moreover, they fail to distinguish semantically similar actions because existing methods typically rely on brief action phrases that lack rich semantic details for action-specific localization. Although large vision-language models (LVLMs) encode rich action semantics and their action-conditioned textual outputs implicitly contain spatial cues, they do not directly provide action-specific spatial localization. To address these problems, we propose TokAG, a zero-shot affordance grounding framework that exploits the token-level semantic-spatial signals in LVLMs to localize action-relevant regions without external supervision. We observe that attention maps associated with different LVLM output tokens vary significantly, with many attending to irrelevant regions such as the background. Thus, we introduce a spatial-aware token-selection mechanism to systematically evaluate each output token and select the one whose attention maps exhibit dominant activation over the target object, instead of relying on arbitrary attention maps. By extracting these object-focused attention maps, we transform the LVLM's implicit semantic signals into zero-shot affordance heatmaps. Our zero-shot framework consistently outperforms prior weakly supervised approaches across multiple benchmarks, improving NSS by 10.7% on the unseen split of AGD20K and by 29.7% on HICO-IIF. The code and models will be made publicly available.

cs.CV

Auto-FL-Research: Agentic Search for Federated Learning Algorithms

Federated learning (FL) research often depends on many small but consequential algorithmic choices: optimizer variants, server aggregation rules, local training schedules, normalization, regularization, and model architecture. These choices are expensive to explore manually and difficult to compare fairly when candidate changes can also alter the FL training or evaluation path. In this work, we present Auto-FL-Research (AFR), a constrained coding-agent workflow for FL algorithmic recipe search. Agents may propose and implement candidate training algorithms, including server aggregation rules, client update schedules, local objectives, and registered model variants, while task profiles fix the mutation surface, compute budget, communication contract, and final model evaluation. Each campaign records candidate scores, runtime, edited files, artifacts, and failure status. We evaluate AFR on five healthcare cross-silo FLamby tasks and on grouped-client profiles for the five fixed LEAF datasets plus the LEAF synthetic task. Five-seed repeat evaluations support gains on four FLamby tasks and five of six LEAF profiles, while also exposing seed-sensitive and search-selected failure cases. Same-budget controls show that several gains correspond to FL-recipe changes, whereas other improvements are recovered by fixed-surface scalar controls or fail under repeat or held-out evaluation. These mixed outcomes are part of the contribution: they show how agent-generated candidates can be separated into repeated FL mechanisms, fixed-surface tuning effects, and selected single-run artifacts.

cs.AI

AutoMedBench: Towards Medical AutoResearch with Agentic AI Models

Autonomous agents are increasingly expected to support end-to-end medical-AI research workflows, moving beyond isolated prediction tasks or short-form clinical question answering. However, existing medical agent benchmarks primarily evaluate final outputs, providing limited visibility into agent behavior within the research process. To address this gap, we present AutoMedBench, a workflow-aware benchmark for autonomous medical-AI research across diverse medical imaging and multimodal inference tasks, organizing agent execution into a unified five-stage workflow (S1-S5): Plan, Setup, Validate, Inference, and Submit. It comprises long-horizon tasks with each run averaging 33 agent turns, spanning five research tracks: segmentation, image enhancement, visual question answering (VQA), report generation, and lesion detection. Each task is evaluated under two difficulty tiers, Lite and Standard, which use the same data and metrics but differ in the amount of task-brief scaffolding, and each run is scored using both final task performance and S1-S5 stage scores, enabling stage-level analysis from the initial task brief to the final submitted artifact. Across thousands of recorded runs, stage-level scoring reveals that Validate is the weakest workflow stage on average, whereas Setup is the strongest, suggesting that current agents are better at making pipelines executable than at verifying their reliability. Post-run error analysis further shows that verification and submission failures dominate tagged errors, accounting for 37.7% and 38.1% of fired codes respectively, whereas task-understanding errors are rare at 0.9%, and runs with one fired error code have a 48% lower overall score than runs with no error code on average.

cs.AI

MedOpenClaw and MedFlowBench: Auditing Medical Agents in Full-Study Workflows

Medical imaging benchmarks often evaluate VLMs on pre-selected 2D images, slices, crops, or patches, making evaluation closer to visual recognition. Real clinical workflows impose a different burden: readers must search through complete studies, operate imaging software, navigate across slices and magnifications, and document visual evidence that can be audited. We argue that this evidence-producing workflow is a critical missing evaluation axis for medical imaging agents. To study it, we introduce MedFlowBench, a full-study benchmark for VLM agents, together with MedOpenClaw, a controlled and replayable runtime in which agents operate medical imaging viewers such as 3D Slicer and QuPath. In each episode, an agent inspects a complete radiology study or whole-slide pathology image, returns a task answer, and submits structured evidence, including key slices, coordinates, regions of interest, or lesion-state fields. This evidence is automatically checked against withheld masks, annotations, and labels. Across evaluated models, final answer-only scoring gives an overly optimistic picture: when answers must also be supported by correct evidence, performance drops substantially on complex workflows. We further find that adding image-analysis tools does not by itself solve the problem. Tools help when they make a complex procedure simple and reliable, but agents still struggle when they must choose inputs, manage viewer state, and verify intermediate outputs over multiple steps. MedFlowBench exposes whether medical imaging agents can produce auditable evidence from complete studies, rather than plausible answers from selected images.

cs.CV

NVILA: Efficient Frontier Visual Language Models

Visual language models (VLMs) have made significant advances in accuracy in recent years. However, their efficiency has received much less attention. This paper introduces NVILA, a family of open VLMs designed to jointly optimize efficiency and accuracy. Building on top of VILA, we improve its model architecture by first scaling up the spatial and temporal resolutions, and then compressing visual tokens. This "scale-then-compress" approach enables NVILA to efficiently process high-resolution images and long videos. We further conduct a systematic investigation that enhances NVILA's efficiency throughout its entire lifecycle, from training and fine-tuning to deployment. NVILA matches or surpasses the accuracy of leading open and proprietary VLMs across a wide range of image and video benchmarks. At the same time, it reduces training cost by 1.9-5.1x, prefilling latency by 1.6-2.2x, and decoding latency by 1.2-2.8x. We release our code and models to facilitate reproducibility.

cs.CV

Distilling Photon-Counting CT into Routine Chest CT through Clinically Validated Degradation Modeling

Photon-counting CT (PCCT) provides superior image quality with higher spatial resolution and lower noise compared to conventional energy-integrating CT (EICT), but its limited clinical availability restricts large-scale research and clinical deployment. To bridge this gap, we propose SUMI, a simulated degradation-to-enhancement method that learns to reverse realistic acquisition artifacts in low-quality EICT by leveraging high-quality PCCT as reference. Our central insight is to explicitly model realistic acquisition degradations, transforming PCCT into clinically plausible lower-quality counterparts and learning to invert this process. The simulated degradations were validated for clinical realism by board-certified radiologists, enabling faithful supervision without requiring paired acquisitions at scale. As outcomes of this technical contribution, we: (1) train a latent diffusion model on 1,046 PCCTs, using an autoencoder first pre-trained on both these PCCTs and 405,379 EICTs from 145 hospitals to extract general CT latent features that we release for reuse in other generative medical imaging tasks; (2) construct a large-scale dataset of over 17,316 publicly available EICTs enhanced to PCCT-like quality, with radiologist-validated voxel-wise annotations of airway trees, arteries, veins, lungs, and lobes; and (3) demonstrate substantial improvements: across external data, SUMI outperforms state-of-the-art image translation methods by 15% in SSIM and 20% in PSNR, improves radiologist-rated clinical utility in reader studies, and enhances downstream top-ranking lesion detection performance, increasing sensitivity by up to 15% and F1 score by up to 10%. Our results suggest that emerging imaging advances can be systematically distilled into routine EICT using limited high-quality scans as reference.

cs.CV

Surg$Σ$: A Spectrum of Large-Scale Multimodal Data and Foundation Models for Surgical Intelligence

Surgical intelligence has the potential to improve the safety and consistency of surgical care, yet most existing surgical AI frameworks remain task-specific and struggle to generalize across procedures and institutions. Although multimodal foundation models, particularly multimodal large language models, have demonstrated strong cross-task capabilities across various medical domains, their advancement in surgery remains constrained by the lack of large-scale, systematically curated multimodal data. To address this challenge, we introduce Surg$Σ$, a spectrum of large-scale multimodal data and foundation models for surgical intelligence. At the core of this framework lies Surg$Σ$-DB, a large-scale multimodal data foundation designed to support diverse surgical tasks. Surg$Σ$-DB consolidates heterogeneous surgical data sources (including open-source datasets, curated in-house clinical collections and web-source data) into a unified schema, aiming to improve label consistency and data standardization across heterogeneous datasets. Surg$Σ$-DB spans 6 clinical specialties and diverse surgical types, providing rich image- and video-level annotations across 18 practical surgical tasks covering understanding, reasoning, planning, and generation, at an unprecedented scale (over 5.98M conversations). Beyond conventional multimodal conversations, Surg$Σ$-DB incorporates hierarchical reasoning annotations, providing richer semantic cues to support deeper contextual understanding in complex surgical scenarios. We further provide empirical evidence through recently developed surgical foundation models built upon Surg$Σ$-DB, illustrating the practical benefits of large-scale multimodal annotations, unified semantic design, and structured reasoning annotations for improving cross-task generalization and interpretability.

cs.AI

Generalized Recognition of Basic Surgical Actions Enables Skill Assessment and Vision-Language-Model-based Surgical Planning

Artificial intelligence, imaging, and large language models have the potential to transform surgical practice, training, and automation. Understanding and modeling of basic surgical actions (BSA), the fundamental unit of operation in any surgery, is important to drive the evolution of this field. In this paper, we present a BSA dataset comprising 10 basic actions across 6 surgical specialties with over 11,000 video clips, which is the largest to date. Based on the BSA dataset, we developed a new foundation model that conducts general-purpose recognition of basic actions. Our approach demonstrates robust cross-specialist performance in experiments validated on datasets from different procedural types and various body parts. Furthermore, we demonstrate downstream applications enabled by the BAS foundation model through surgical skill assessment in prostatectomy using domain-specific knowledge, and action planning in cholecystectomy and nephrectomy using large vision-language models. Multinational surgeons' evaluation of the language model's output of the action planning explainable texts demonstrated clinical relevance. These findings indicate that basic surgical actions can be robustly recognized across scenarios, and an accurate BSA understanding model can essentially facilitate complex applications and speed up the realization of surgical superintelligence.

cs.CV

SAW: Toward a Surgical Action World Model via Controllable and Scalable Video Generation

A surgical world model capable of generating realistic surgical action videos with precise control over tool-tissue interactions can address fundamental challenges in surgical AI and simulation -- from data scarcity and rare event synthesis to bridging the sim-to-real gap for surgical automation. However, current video generation methods, the very core of such surgical world models, require expensive annotations or complex structured intermediates as conditioning signals at inference, limiting their scalability. Other approaches exhibit limited temporal consistency across complex laparoscopic scenes and do not possess sufficient realism. We propose Surgical Action World (SAW) -- a step toward surgical action world modeling through video diffusion conditioned on four lightweight signals: language prompts encoding tool-action context, a reference surgical scene, tissue affordance mask, and 2D tool-tip trajectories. We design a conditional video diffusion approach that reformulates video-to-video diffusion into trajectory-conditioned surgical action synthesis. The backbone diffusion model is fine-tuned on a custom-curated dataset of 12,044 laparoscopic clips with lightweight spatiotemporal conditioning signals, leveraging a depth consistency loss to enforce geometric plausibility without requiring depth at inference. SAW achieves state-of-the-art temporal consistency (CD-FVD: 199.19 vs. 546.82) and strong visual quality on held-out test data. Furthermore, we demonstrate its downstream utility for (a) surgical AI, where augmenting rare actions with SAW-generated videos improves action recognition (clipping F1-score: 20.93% to 43.14%; cutting: 0.00% to 8.33%) on real test data, and (b) surgical simulation, where rendering tool-tissue interaction videos from simulator-derived trajectory points toward a visually faithful simulation engine.

cs.CV

SDUM: A Scalable Deep Unrolled Model for Universal MRI Reconstruction

Clinical MRI encompasses diverse imaging protocols--spanning anatomical targets (cardiac, brain, knee), contrasts (T1, T2, mapping), sampling patterns (Cartesian, radial, spiral, kt-space), and acceleration factors--yet current deep learning reconstructions are typically protocol-specific, hindering generalization and deployment. We introduce Scalable Deep Unrolled Model (SDUM), a universal framework combining a Restormer-based reconstructor, a learned coil sensitivity map estimator (CSME), sampling-aware weighted data consistency (SWDC), universal conditioning (UC) on cascade index and protocol metadata, and progressive cascade expansion training. SDUM exhibits foundation-model-like scaling behavior: reconstruction quality follows PSNR ${\sim}$ log(parameters) with correlation $r{=}0.986$ ($R^2{=}0.973$) up to 18 cascades, demonstrating predictable performance gains with model depth. A single SDUM trained on heterogeneous data achieves state-of-the-art results across all four CMRxRecon2025 challenge tracks--multi-center, multi-disease, 5T, and pediatric--without task-specific fine-tuning, surpassing specialized baselines by up to ${+}1.0$~dB. On CMRxRecon2024, SDUM outperforms the winning method PromptMR+ by ${+}0.55$~dB; on fastMRI brain, it exceeds PC-RNN by ${+}1.8$~dB. Ablations validate each component: SWDC ${+}0.43$~dB over standard DC, per-cascade CSME ${+}0.51$~dB, UC ${+}0.38$~dB. These results establish SDUM as a practical path toward universal, scalable MRI reconstruction.

cs.CV

Surg-R1: A Hierarchical Reasoning Foundation Model for Scalable and Interpretable Surgical Decision Support with Multi-Center Clinical Validation

Surgical scene understanding demands not only accurate predictions but also interpretable reasoning that surgeons can verify against clinical expertise. However, existing surgical vision-language models generate predictions without reasoning chains, and general-purpose reasoning models fail on compositional surgical tasks without domain-specific knowledge. We present Surg-R1, a surgical Vision-Language Model that addresses this gap through hierarchical reasoning trained via a four-stage pipeline. Our approach introduces three key contributions: (1) a three-level reasoning hierarchy decomposing surgical interpretation into perceptual grounding, relational understanding, and contextual reasoning; (2) the largest surgical chain-of-thought dataset with 320,000 reasoning pairs; and (3) a four-stage training pipeline progressing from supervised fine-tuning to group relative policy optimization and iterative self-improvement. Evaluation on SurgBench, comprising six public benchmarks and six multi-center external validation datasets from five institutions, demonstrates that Surg-R1 achieves the highest Arena Score (64.9%) on public benchmarks versus Gemini 3.0 Pro (46.1%) and GPT-5.1 (37.9%), outperforming both proprietary reasoning models and specialized surgical VLMs on the majority of tasks spanning instrument localization, triplet recognition, phase recognition, action recognition, and critical view of safety assessment, with a 15.2 percentage point improvement over the strongest surgical baseline on external validation.

cs.CV

Cosmos-H-Surgical: Learning Surgical Robot Policies from Videos via World Modeling

Data scarcity remains a fundamental barrier to achieving fully autonomous surgical robots. While large scale vision language action (VLA) models have shown impressive generalization in household and industrial manipulation by leveraging paired video action data from diverse domains, surgical robotics suffers from the paucity of datasets that include both visual observations and accurate robot kinematics. In contrast, vast corpora of surgical videos exist, but they lack corresponding action labels, preventing direct application of imitation learning or VLA training. In this work, we aim to alleviate this problem by learning policy models from Cosmos-H-Surgical, a world model designed for surgical physical AI. We curated the Surgical Action Text Alignment (SATA) dataset with detailed action description specifically for surgical robots. Then we built Cosmos-H-Surgical based on the most advanced physical AI world model and SATA. It's able to generate diverse, generalizable and realistic surgery videos. We are also the first to use an inverse dynamics model to infer pseudokinematics from synthetic surgical videos, producing synthetic paired video action data. We demonstrate that a surgical VLA policy trained with these augmented data significantly outperforms models trained only on real demonstrations on a real surgical robot platform. Our approach offers a scalable path toward autonomous surgical skill acquisition by leveraging the abundance of unlabeled surgical video and generative world modeling, thus opening the door to generalizable and data efficient surgical robot policies.

cs.RO

Humanoid Robots as First Assistants in Endoscopic Surgery

Humanoid robots have become a focal point of technological ambition, with claims of surgical capability within years in mainstream discourse. These projections are aspirational yet lack empirical grounding. To date, no humanoid has assisted a surgeon through an actual procedure, let alone performed one. The work described here breaks this new ground. Here we report a proof of concept in which a teleoperated Unitree G1 provided endoscopic visualization while an attending otolaryngologist performed a cadaveric sphenoidectomy. The procedure was completed successfully, with stable visualization maintained throughout. Teleoperation allowed assessment of whether the humanoid form factor could meet the physical demands of surgical assistance in terms of sustenance and precision; the cognitive demands were satisfied -- for now -- by the operator. Post-procedure analysis identified engineering targets for clinical translation, alongside near-term opportunities such as autonomous diagnostic scoping. This work establishes form-factor feasibility for humanoid surgical assistance while identifying challenges for continued development.

cs.RO

LUMEN: Longitudinal Multi-Modal Radiology Model for Prognosis and Diagnosis

Large vision-language models (VLMs) have evolved from general-purpose applications to specialized use cases such as in the clinical domain, demonstrating potential for decision support in radiology. One promising application is assisting radiologists in decision-making by the analysis of radiology imaging data such as chest X-rays (CXR) via a visual and natural language question-answering (VQA) interface. When longitudinal imaging is available, radiologists analyze temporal changes, which are essential for accurate diagnosis and prognosis. The manual longitudinal analysis is a time-consuming process, motivating the development of a training framework that can provide prognostic capabilities. We introduce a novel training framework LUMEN, that is optimized for longitudinal CXR interpretation, leveraging multi-image and multi-task instruction fine-tuning to enhance prognostic and diagnostic performance. We conduct experiments on the publicly available MIMIC-CXR and its associated Medical-Diff-VQA datasets. We further formulate and construct a novel instruction-following dataset incorporating longitudinal studies, enabling the development of a prognostic VQA task. Our method demonstrates significant improvements over baseline models in diagnostic VQA tasks, and more importantly, shows promising potential for prognostic capabilities. These results underscore the value of well-designed, instruction-tuned VLMs in enabling more accurate and clinically meaningful radiological interpretation of longitudinal radiological imaging data.

cs.CV

VISTA-PATH: An interactive foundation model for pathology image segmentation and quantitative analysis in computational pathology

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet remain poorly aligned with pathology because they treat segmentation as a static visual prediction task. Here we present VISTA-PATH, an interactive, class-aware pathology segmentation foundation model designed to resolve heterogeneous structures, incorporate expert feedback, and produce pixel-level segmentation that are directly meaningful for clinical interpretation. VISTA-PATH jointly conditions segmentation on visual context, semantic tissue descriptions, and optional expert-provided spatial prompts, enabling precise multi-class segmentation across heterogeneous pathology images. To support this paradigm, we curate VISTA-PATH Data, a large-scale pathology segmentation corpus comprising over 1.6 million image-mask-text triplets spanning 9 organs and 93 tissue classes. Across extensive held-out and external benchmarks, VISTA-PATH consistently outperforms existing segmentation foundation models. Importantly, VISTA-PATH supports dynamic human-in-the-loop refinement by propagating sparse, patch-level bounding-box annotation feedback into whole-slide segmentation. Finally, we show that the high-fidelity, class-aware segmentation produced by VISTA-PATH is a preferred model for computational pathology. It improve tissue microenvironment analysis through proposed Tumor Interaction Score (TIS), which exhibits strong and significant associations with patient survival. Together, these results establish VISTA-PATH as a foundation model that elevates pathology image segmentation from a static prediction to an interactive and clinically grounded representation for digital pathology. Source code and demo can be found at https://github.com/zhihuanglab/VISTA-PATH.

cs.CV