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David Gotz

Publications and source records attributed to David Gotz.

26 records · Page 2Linked to original sources

Selection-Bias-Corrected Visualization via Dynamic Reweighting

The collection and visual analysis of large-scale data from complex systems, such as electronic health records or clickstream data, has become increasingly common across a wide range of industries. This type of retrospective visual analysis, however, is prone to a variety of selection bias effects, especially for high-dimensional data where only a subset of dimensions is visualized at any given time. The risk of selection bias is even higher when analysts dynamically apply filters or perform grouping operations during ad hoc analyses. These bias effects threatens the validity and generalizability of insights discovered during visual analysis as the basis for decision making. Past work has focused on bias transparency, helping users understand when selection bias may have occurred. However, countering the effects of selection bias via bias mitigation is typically left for the user to accomplish as a separate process. Dynamic reweighting (DR) is a novel computational approach to selection bias mitigation that helps users craft bias-corrected visualizations. This paper describes the DR workflow, introduces key DR visualization designs, and presents statistical methods that support the DR process. Use cases from the medical domain, as well as findings from domain expert user interviews, are also reported.

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Survey on Visual Analysis of Event Sequence Data

Event sequence data record series of discrete events in the time order of occurrence. They are commonly observed in a variety of applications ranging from electronic health records to network logs, with the characteristics of large-scale, high-dimensional, and heterogeneous. This high complexity of event sequence data makes it difficult for analysts to manually explore and find patterns, resulting in ever-increasing needs for computational and perceptual aids from visual analytics techniques to extract and communicate insights from event sequence datasets. In this paper, we review the state-of-the-art visual analytics approaches, characterize them with our proposed design space, and categorize them based on analytical tasks and applications. From our review of relevant literature, we have also identified several remaining research challenges and future research opportunities.

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Selection Bias Tracking and Detailed Subset Comparison for High-Dimensional Data

The collection of large, complex datasets has become common across a wide variety of domains. Visual analytics tools increasingly play a key role in exploring and answering complex questions about these large datasets. However, many visualizations are not designed to concurrently visualize the large number of dimensions present in complex datasets (e.g. tens of thousands of distinct codes in an electronic health record system). This fact, combined with the ability of many visual analytics systems to enable rapid, ad-hoc specification of groups, or cohorts, of individuals based on a small subset of visualized dimensions, leads to the possibility of introducing selection bias--when the user creates a cohort based on a specified set of dimensions, differences across many other unseen dimensions may also be introduced. These unintended side effects may result in the cohort no longer being representative of the larger population intended to be studied, which can negatively affect the validity of subsequent analyses. We present techniques for selection bias tracking and visualization that can be incorporated into high-dimensional exploratory visual analytics systems, with a focus on medical data with existing data hierarchies. These techniques include: (1) tree-based cohort provenance and visualization, with a user-specified baseline cohort that all other cohorts are compared against, and visual encoding of the drift for each cohort, which indicates where selection bias may have occurred, and (2) a set of visualizations, including a novel icicle-plot based visualization, to compare in detail the per-dimension differences between the baseline and a user-specified focus cohort. These techniques are integrated into a medical temporal event sequence visual analytics tool. We present example use cases and report findings from domain expert user interviews.

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Visual Anomaly Detection in Event Sequence Data

Anomaly detection is a common analytical task that aims to identify rare cases that differ from the typical cases that make up the majority of a dataset. When applied to the analysis of event sequence data, the task of anomaly detection can be complex because the sequential and temporal nature of such data results in diverse definitions and flexible forms of anomalies. This, in turn, increases the difficulty in interpreting detected anomalies. In this paper, we propose an unsupervised anomaly detection algorithm based on Variational AutoEncoders (VAE) to estimate underlying normal progressions for each given sequence represented as occurrence probabilities of events along the sequence progression. Events in violation of their occurrence probability are identified as abnormal. We also introduce a visualization system, EventThread3, to support interactive exploration and interpretations of anomalies within the context of normal sequence progressions in the dataset through comprehensive one-to-many sequence comparison. Finally, we quantitatively evaluate the performance of our anomaly detection algorithm and demonstrate the effectiveness of our system through a case study.

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Periphery Plots for Contextualizing Heterogeneous Time-Based Charts

Patterns in temporal data can often be found across different scales, such as days, weeks, and months, making effective visualization of time-based data challenging. Here we propose a new approach for providing focus and context in time-based charts to enable interpretation of patterns across time scales. Our approach employs a focus zone with a time and a second axis, that can either represent quantities or categories, as well as a set of adjacent periphery plots that can aggregate data along the time, value, or both dimensions. We present a framework for periphery plots and describe two use cases that demonstrate the utility of our approach.

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Visual Analysis of High-Dimensional Event Sequence Data via Dynamic Hierarchical Aggregation

Temporal event data are collected across a broad range of domains, and a variety of visual analytics techniques have been developed to empower analysts working with this form of data. These techniques generally display aggregate statistics computed over sets of event sequences that share common patterns. Such techniques are often hindered, however, by the high-dimensionality of many real-world event sequence datasets because the large number of distinct event types within such data prevents effective aggregation. A common coping strategy for this challenge is to group event types together as a pre-process, prior to visualization, so that each group can be represented within an analysis as a single event type. However, computing these event groupings as a pre-process also places significant constraints on the analysis. This paper presents a dynamic hierarchical aggregation technique that leverages a predefined hierarchy of dimensions to computationally quantify the informativeness of alternative levels of grouping within the hierarchy at runtime. This allows users to dynamically explore the hierarchy to select the most appropriate level of grouping to use at any individual step within an analysis. Key contributions include an algorithm for interactively determining the most informative set of event groupings from within a large-scale hierarchy of event types, and a scatter-plus-focus visualization that supports interactive hierarchical exploration. While these contributions are generalizable to other types of problems, we apply them to high-dimensional event sequence analysis using large-scale event type hierarchies from the medical domain. We describe their use within a medical cohort analysis tool called Cadence, demonstrate an example in which the proposed technique supports better views of event sequence data, and report findings from domain expert interviews.

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CarePre: An Intelligent Clinical Decision Assistance System

Clinical decision support systems (CDSS) are widely used to assist with medical decision making. However, CDSS typically require manually curated rules and other data which are difficult to maintain and keep up-to-date. Recent systems leverage advanced deep learning techniques and electronic health records (EHR) to provide more timely and precise results. Many of these techniques have been developed with a common focus on predicting upcoming medical events. However, while the prediction results from these approaches are promising, their value is limited by their lack of interpretability. To address this challenge, we introduce CarePre, an intelligent clinical decision assistance system. The system extends a state-of-the-art deep learning model to predict upcoming diagnosis events for a focal patient based on his/her historical medical records. The system includes an interactive framework together with intuitive visualizations designed to support the diagnosis, treatment outcome analysis, and the interpretation of the analysis results. We demonstrate the effectiveness and usefulness of CarePre system by reporting results from a quantities evaluation of the prediction algorithm and a case study and three interviews with senior physicians.

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Visual Model Validation via Inline Replication

Data visualizations typically show retrospective views of an existing dataset with little or no focus on repeatability. However, consumers of these tools often use insights gleaned from retrospective visualizations as the basis for decisions about future events. In this way, visualizations often serve as visual predictive models despite the fact that they are typically designed to present historical views of the data. This "visual predictive model" approach, however, can lead to invalid inferences. In this paper, we describe an approach to visual model validation called Inline Replication (IR) which, similar to the cross-validation technique used widely in machine learning, provides a nonparametric and broadly applicable technique for visual model assessment and repeatability. This paper describes the overall IR process and outlines how it can be integrated into both traditional and emerging "big data" visualization pipelines. Examples are provided showing IR integrated within common visualization techniques (such as bar charts and linear regression lines) as well as a more fully-featured visualization system designed for complex exploratory analysis tasks.

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