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Fei Shen

Publications and source records attributed to Fei Shen.

At least 109 records · Page 6Linked to original sources

Artificial Intelligence for Central Dogma-Centric Multi-Omics: Challenges and Breakthroughs

With the rapid development of high-throughput sequencing platforms, an increasing number of omics technologies, such as genomics, metabolomics, and transcriptomics, are being applied to disease genetics research. However, biological data often exhibit high dimensionality and significant noise, making it challenging to effectively distinguish disease subtypes using a single-omics approach. To address these challenges and better capture the interactions among DNA, RNA, and proteins described by the central dogma, numerous studies have leveraged artificial intelligence to develop multi-omics models for disease research. These AI-driven models have improved the accuracy of disease prediction and facilitated the identification of genetic loci associated with diseases, thus advancing precision medicine. This paper reviews the mathematical definitions of multi-omics, strategies for integrating multi-omics data, applications of artificial intelligence and deep learning in multi-omics, the establishment of foundational models, and breakthroughs in multi-omics technologies, drawing insights from over 130 related articles. It aims to provide practical guidance for computational biologists to better understand and effectively utilize AI-based multi-omics machine learning algorithms in the context of central dogma.

q-bio.GN↗

Advancing Pose-Guided Image Synthesis with Progressive Conditional Diffusion Models

Recent work has showcased the significant potential of diffusion models in pose-guided person image synthesis. However, owing to the inconsistency in pose between the source and target images, synthesizing an image with a distinct pose, relying exclusively on the source image and target pose information, remains a formidable challenge. This paper presents Progressive Conditional Diffusion Models (PCDMs) that incrementally bridge the gap between person images under the target and source poses through three stages. Specifically, in the first stage, we design a simple prior conditional diffusion model that predicts the global features of the target image by mining the global alignment relationship between pose coordinates and image appearance. Then, the second stage establishes a dense correspondence between the source and target images using the global features from the previous stage, and an inpainting conditional diffusion model is proposed to further align and enhance the contextual features, generating a coarse-grained person image. In the third stage, we propose a refining conditional diffusion model to utilize the coarsely generated image from the previous stage as a condition, achieving texture restoration and enhancing fine-detail consistency. The three-stage PCDMs work progressively to generate the final high-quality and high-fidelity synthesized image. Both qualitative and quantitative results demonstrate the consistency and photorealism of our proposed PCDMs under challenging scenarios.The code and model will be available at https://github.com/tencent-ailab/PCDMs.

cs.CV↗

SPEAK: Speech-Driven Pose and Emotion-Adjustable Talking Head Generation

Most earlier researches on talking face generation have focused on the synchronization of lip motion and speech content. However, head pose and facial emotions are equally important characteristics of natural faces. While audio-driven talking face generation has seen notable advancements, existing methods either overlook facial emotions or are limited to specific individuals and cannot be applied to arbitrary subjects. In this paper, we propose a novel one-shot Talking Head Generation framework (SPEAK) that distinguishes itself from the general Talking Face Generation by enabling emotional and postural control. Specifically, we introduce Inter-Reconstructed Feature Disentanglement (IRFD) module to decouple facial features into three latent spaces. Then we design a face editing module that modifies speech content and facial latent codes into a single latent space. Subsequently, we present a novel generator that employs modified latent codes derived from the editing module to regulate emotional expression, head poses, and speech content in synthesizing facial animations. Extensive trials demonstrate that our method ensures lip synchronization with the audio while enabling decoupled control of facial features, it can generate realistic talking head with coordinated lip motions, authentic facial emotions, and smooth head movements. The demo video is available: https://anonymous.4open.science/r/SPEAK-8A22

cs.CV↗

Lesion-aware network for diabetic retinopathy diagnosis

Deep learning brought boosts to auto diabetic retinopathy (DR) diagnosis, thus, greatly helping ophthalmologists for early disease detection, which contributes to preventing disease deterioration that may eventually lead to blindness. It has been proved that convolutional neural network (CNN)-aided lesion identifying or segmentation benefits auto DR screening. The key to fine-grained lesion tasks mainly lies in: (1) extracting features being both sensitive to tiny lesions and robust against DR-irrelevant interference, and (2) exploiting and re-using encoded information to restore lesion locations under extremely imbalanced data distribution. To this end, we propose a CNN-based DR diagnosis network with attention mechanism involved, termed lesion-aware network, to better capture lesion information from imbalanced data. Specifically, we design the lesion-aware module (LAM) to capture noise-like lesion areas across deeper layers, and the feature-preserve module (FPM) to assist shallow-to-deep feature fusion. Afterward, the proposed lesion-aware network (LANet) is constructed by embedding the LAM and FPM into the CNN decoders for DR-related information utilization. The proposed LANet is then further extended to a DR screening network by adding a classification layer. Through experiments on three public fundus datasets with pixel-level annotations, our method outperforms the mainstream methods with an area under curve of 0.967 in DR screening, and increases the overall average precision by 7.6%, 2.1%, and 1.2% in lesion segmentation on three datasets. Besides, the ablation study validates the effectiveness of the proposed sub-modules.

eess.IV↗

SHREC: a SRE Behaviour Knowledge Graph Model for Shell Command Recommendations

In IT system operations, shell commands are common command line tools used by site reliability engineers (SREs) for daily tasks, such as system configuration, package deployment, and performance optimization. The efficiency in their execution has a crucial business impact since shell commands very often aim to execute critical operations, such as the resolution of system faults. However, many shell commands involve long parameters that make them hard to remember and type. Additionally, the experience and knowledge of SREs using these commands are almost always not preserved. In this work, we propose SHREC, a SRE behaviour knowledge graph model for shell command recommendations. We model the SRE shell behaviour knowledge as a knowledge graph and propose a strategy to directly extract such a knowledge from SRE historical shell operations. The knowledge graph is then used to provide shell command recommendations in real-time to improve the SRE operation efficiency. Our empirical study based on real shell commands executed in our company demonstrates that SHREC can improve the SRE operation efficiency, allowing to share and re-utilize the SRE knowledge.

cs.SE↗

IMAGDressing-v1: Customizable Virtual Dressing

Latest advances have achieved realistic virtual try-on (VTON) through localized garment inpainting using latent diffusion models, significantly enhancing consumers' online shopping experience. However, existing VTON technologies neglect the need for merchants to showcase garments comprehensively, including flexible control over garments, optional faces, poses, and scenes. To address this issue, we define a virtual dressing (VD) task focused on generating freely editable human images with fixed garments and optional conditions. Meanwhile, we design a comprehensive affinity metric index (CAMI) to evaluate the consistency between generated images and reference garments. Then, we propose IMAGDressing-v1, which incorporates a garment UNet that captures semantic features from CLIP and texture features from VAE. We present a hybrid attention module, including a frozen self-attention and a trainable cross-attention, to integrate garment features from the garment UNet into a frozen denoising UNet, ensuring users can control different scenes through text. IMAGDressing-v1 can be combined with other extension plugins, such as ControlNet and IP-Adapter, to enhance the diversity and controllability of generated images. Furthermore, to address the lack of data, we release the interactive garment pairing (IGPair) dataset, containing over 300,000 pairs of clothing and dressed images, and establish a standard pipeline for data assembly. Extensive experiments demonstrate that our IMAGDressing-v1 achieves state-of-the-art human image synthesis performance under various controlled conditions. The code and model will be available at https://github.com/muzishen/IMAGDressing.

cs.CV↗

Few-shot Defect Image Generation based on Consistency Modeling

Image generation can solve insufficient labeled data issues in defect detection. Most defect generation methods are only trained on a single product without considering the consistencies among multiple products, leading to poor quality and diversity of generated results. To address these issues, we propose DefectDiffu, a novel text-guided diffusion method to model both intra-product background consistency and inter-product defect consistency across multiple products and modulate the consistency perturbation directions to control product type and defect strength, achieving diversified defect image generation. Firstly, we leverage a text encoder to separately provide consistency prompts for background, defect, and fusion parts of the disentangled integrated architecture, thereby disentangling defects and normal backgrounds. Secondly, we propose the double-free strategy to generate defect images through two-stage perturbation of consistency direction, thereby controlling product type and defect strength by adjusting the perturbation scale. Besides, DefectDiffu can generate defect mask annotations utilizing cross-attention maps from the defect part. Finally, to improve the generation quality of small defects and masks, we propose the adaptive attention-enhance loss to increase the attention to defects. Experimental results demonstrate that DefectDiffu surpasses state-of-the-art methods in terms of generation quality and diversity, thus effectively improving downstream defection performance. Moreover, defect perturbation directions can be transferred among various products to achieve zero-shot defect generation, which is highly beneficial for addressing insufficient data issues. The code are available at https://github.com/FFDD-diffusion/DefectDiffu.

cs.CV↗

VCP-CLIP: A visual context prompting model for zero-shot anomaly segmentation

Recently, large-scale vision-language models such as CLIP have demonstrated immense potential in zero-shot anomaly segmentation (ZSAS) task, utilizing a unified model to directly detect anomalies on any unseen product with painstakingly crafted text prompts. However, existing methods often assume that the product category to be inspected is known, thus setting product-specific text prompts, which is difficult to achieve in the data privacy scenarios. Moreover, even the same type of product exhibits significant differences due to specific components and variations in the production process, posing significant challenges to the design of text prompts. In this end, we propose a visual context prompting model (VCP-CLIP) for ZSAS task based on CLIP. The insight behind VCP-CLIP is to employ visual context prompting to activate CLIP's anomalous semantic perception ability. In specific, we first design a Pre-VCP module to embed global visual information into the text prompt, thus eliminating the necessity for product-specific prompts. Then, we propose a novel Post-VCP module, that adjusts the text embeddings utilizing the fine-grained features of the images. In extensive experiments conducted on 10 real-world industrial anomaly segmentation datasets, VCP-CLIP achieved state-of-the-art performance in ZSAS task. The code is available at https://github.com/xiaozhen228/VCP-CLIP.

cs.CV↗

Boosting Consistency in Story Visualization with Rich-Contextual Conditional Diffusion Models

Recent research showcases the considerable potential of conditional diffusion models for generating consistent stories. However, current methods, which predominantly generate stories in an autoregressive and excessively caption-dependent manner, often underrate the contextual consistency and relevance of frames during sequential generation. To address this, we propose a novel Rich-contextual Conditional Diffusion Models (RCDMs), a two-stage approach designed to enhance story generation's semantic consistency and temporal consistency. Specifically, in the first stage, the frame-prior transformer diffusion model is presented to predict the frame semantic embedding of the unknown clip by aligning the semantic correlations between the captions and frames of the known clip. The second stage establishes a robust model with rich contextual conditions, including reference images of the known clip, the predicted frame semantic embedding of the unknown clip, and text embeddings of all captions. By jointly injecting these rich contextual conditions at the image and feature levels, RCDMs can generate semantic and temporal consistency stories. Moreover, RCDMs can generate consistent stories with a single forward inference compared to autoregressive models. Our qualitative and quantitative results demonstrate that our proposed RCDMs outperform in challenging scenarios. The code and model will be available at https://github.com/muzishen/RCDMs.

cs.CV↗

V-Express: Conditional Dropout for Progressive Training of Portrait Video Generation

In the field of portrait video generation, the use of single images to generate portrait videos has become increasingly prevalent. A common approach involves leveraging generative models to enhance adapters for controlled generation. However, control signals (e.g., text, audio, reference image, pose, depth map, etc.) can vary in strength. Among these, weaker conditions often struggle to be effective due to interference from stronger conditions, posing a challenge in balancing these conditions. In our work on portrait video generation, we identified audio signals as particularly weak, often overshadowed by stronger signals such as facial pose and reference image. However, direct training with weak signals often leads to difficulties in convergence. To address this, we propose V-Express, a simple method that balances different control signals through the progressive training and the conditional dropout operation. Our method gradually enables effective control by weak conditions, thereby achieving generation capabilities that simultaneously take into account the facial pose, reference image, and audio. The experimental results demonstrate that our method can effectively generate portrait videos controlled by audio. Furthermore, a potential solution is provided for the simultaneous and effective use of conditions of varying strengths.

cs.CV↗

LR-FPN: Enhancing Remote Sensing Object Detection with Location Refined Feature Pyramid Network

Remote sensing target detection aims to identify and locate critical targets within remote sensing images, finding extensive applications in agriculture and urban planning. Feature pyramid networks (FPNs) are commonly used to extract multi-scale features. However, existing FPNs often overlook extracting low-level positional information and fine-grained context interaction. To address this, we propose a novel location refined feature pyramid network (LR-FPN) to enhance the extraction of shallow positional information and facilitate fine-grained context interaction. The LR-FPN consists of two primary modules: the shallow position information extraction module (SPIEM) and the contextual interaction module (CIM). Specifically, SPIEM first maximizes the retention of solid location information of the target by simultaneously extracting positional and saliency information from the low-level feature map. Subsequently, CIM injects this robust location information into different layers of the original FPN through spatial and channel interaction, explicitly enhancing the object area. Moreover, in spatial interaction, we introduce a simple local and non-local interaction strategy to learn and retain the saliency information of the object. Lastly, the LR-FPN can be readily integrated into common object detection frameworks to improve performance significantly. Extensive experiments on two large-scale remote sensing datasets (i.e., DOTAV1.0 and HRSC2016) demonstrate that the proposed LR-FPN is superior to state-of-the-art object detection approaches. Our code and models will be publicly available.

cs.CV↗

Low-Complexity Estimation Algorithm and Decoupling Scheme for FRaC System

With the leaping advances in autonomous vehicles and transportation infrastructure, dual function radar-communication (DFRC) systems have become attractive due to the size, cost and resource efficiency. A frequency modulated continuous waveform (FMCW)-based radar-communication system (FRaC) utilizing both sparse multiple-input and multiple-output (MIMO) arrays and index modulation (IM) has been proposed to form a DFRC system specifically designed for vehicular applications. In this paper, the three-dimensional (3D) parameter estimation problem in the FRaC is considered. Since the 3D-parameters including range, direction of arrival (DOA) and velocity are coupled in the estimating matrix of the FRaC system, the existing estimation algorithms cannot estimate the 3D-parameters accurately. Hence, a novel decomposed decoupled atomic norm minimization (DANM) method is proposed by splitting the 3D-parameter estimating matrix into multiple 2D matrices with sparsity constraints. Then, the 3D-parameters are estimated and efficiently and separately with the optimized decoupled estimating matrix. Moreover, the Cramér-Rao lower bound (CRLB) of the 3D-parameter estimation are derived, and the computational complexity of the proposed algorithm is analyzed. Simulation results show that the proposed decomposed DANM method exploits the advantage of the virtual aperture in the existence of coupling caused by IM and sparse MIMO array and outperforms the co-estimation algorithm with lower computation complexity.

eess.SP↗

Investigating Shift Equivalence of Convolutional Neural Networks in Industrial Defect Segmentation

In industrial defect segmentation tasks, while pixel accuracy and Intersection over Union (IoU) are commonly employed metrics to assess segmentation performance, the output consistency (also referred to equivalence) of the model is often overlooked. Even a small shift in the input image can yield significant fluctuations in the segmentation results. Existing methodologies primarily focus on data augmentation or anti-aliasing to enhance the network's robustness against translational transformations, but their shift equivalence performs poorly on the test set or is susceptible to nonlinear activation functions. Additionally, the variations in boundaries resulting from the translation of input images are consistently disregarded, thus imposing further limitations on the shift equivalence. In response to this particular challenge, a novel pair of down/upsampling layers called component attention polyphase sampling (CAPS) is proposed as a replacement for the conventional sampling layers in CNNs. To mitigate the effect of image boundary variations on the equivalence, an adaptive windowing module is designed in CAPS to adaptively filter out the border pixels of the image. Furthermore, a component attention module is proposed to fuse all downsampled features to improve the segmentation performance. The experimental results on the micro surface defect (MSD) dataset and four real-world industrial defect datasets demonstrate that the proposed method exhibits higher equivalence and segmentation performance compared to other state-of-the-art methods.Our code will be available at https://github.com/xiaozhen228/CAPS.

cs.CV↗

Exploring the Optimization Objective of One-Class Classification for Anomaly Detection

One-class classification (OCC) is a longstanding method for anomaly detection. With the powerful representation capability of the pre-trained backbone, OCC methods have witnessed significant performance improvements. Typically, most of these OCC methods employ transfer learning to enhance the discriminative nature of the pre-trained backbone's features, thus achieving remarkable efficacy. While most current approaches emphasize feature transfer strategies, we argue that the optimization objective space within OCC methods could also be an underlying critical factor influencing performance. In this work, we conducted a thorough investigation into the optimization objective of OCC. Through rigorous theoretical analysis and derivation, we unveil a key insights: any space with the suitable norm can serve as an equivalent substitute for the hypersphere center, without relying on the distribution assumption of training samples. Further, we provide guidelines for determining the feasible domain of norms for the OCC optimization objective. This novel insight sparks a simple and data-agnostic deep one-class classification method. Our method is straightforward, with a single 1x1 convolutional layer as a trainable projector and any space with suitable norm as the optimization objective. Extensive experiments validate the reliability and efficacy of our findings and the corresponding methodology, resulting in state-of-the-art performance in both one-class classification and industrial vision anomaly detection and segmentation tasks.

cs.CV↗

The Second-place Solution for CVPR VISION 23 Challenge Track 1 -- Data Effificient Defect Detection

The Vision Challenge Track 1 for Data-Effificient Defect Detection requires competitors to instance segment 14 industrial inspection datasets in a data-defificient setting. This report introduces the technical details of the team Aoi-overfifitting-Team for this challenge. Our method focuses on the key problem of segmentation quality of defect masks in scenarios with limited training samples. Based on the Hybrid Task Cascade (HTC) instance segmentation algorithm, we connect the transformer backbone (Swin-B) through composite connections inspired by CBNetv2 to enhance the baseline results. Additionally, we propose two model ensemble methods to further enhance the segmentation effect: one incorporates semantic segmentation into instance segmentation, while the other employs multi-instance segmentation fusion algorithms. Finally, using multi-scale training and test-time augmentation (TTA), we achieve an average mAP@0.50:0.95 of more than 48.49% and an average mAR@0.50:0.95 of 66.71% on the test set of the Data Effificient Defect Detection Challenge. The code is available at https://github.com/love6tao/Aoi-overfitting-team

cs.CV↗

Towards Total Online Unsupervised Anomaly Detection and Localization in Industrial Vision

Although existing image anomaly detection methods yield impressive results, they are mostly an offline learning paradigm that requires excessive data pre-collection, limiting their adaptability in industrial scenarios with online streaming data. Online learning-based image anomaly detection methods are more compatible with industrial online streaming data but are rarely noticed. For the first time, this paper presents a fully online learning image anomaly detection method, namely LeMO, learning memory for online image anomaly detection. LeMO leverages learnable memory initialized with orthogonal random noise, eliminating the need for excessive data in memory initialization and circumventing the inefficiencies of offline data collection. Moreover, a contrastive learning-based loss function for anomaly detection is designed to enable online joint optimization of memory and image target-oriented features. The presented method is simple and highly effective. Extensive experiments demonstrate the superior performance of LeMO in the online setting. Additionally, in the offline setting, LeMO is also competitive with the current state-of-the-art methods and achieves excellent performance in few-shot scenarios.

cs.CV↗

Triplet Contrastive Representation Learning for Unsupervised Vehicle Re-identification

Part feature learning is critical for fine-grained semantic understanding in vehicle re-identification. However, existing approaches directly model part features and global features, which can easily lead to serious gradient vanishing issues due to their unequal feature information and unreliable pseudo-labels for unsupervised vehicle re-identification. To address this problem, in this paper, we propose a simple Triplet Contrastive Representation Learning (TCRL) framework which leverages cluster features to bridge the part features and global features for unsupervised vehicle re-identification. Specifically, TCRL devises three memory banks to store the instance/cluster features and proposes a Proxy Contrastive Loss (PCL) to make contrastive learning between adjacent memory banks, thus presenting the associations between the part and global features as a transition of the part-cluster and cluster-global associations. Since the cluster memory bank copes with all the vehicle features, it can summarize them into a discriminative feature representation. To deeply exploit the instance/cluster information, TCRL proposes two additional loss functions. For the instance-level feature, a Hybrid Contrastive Loss (HCL) re-defines the sample correlations by approaching the positive instance features and pushing the all negative instance features away. For the cluster-level feature, a Weighted Regularization Cluster Contrastive Loss (WRCCL) refines the pseudo labels by penalizing the mislabeled images according to the instance similarity. Extensive experiments show that TCRL outperforms many state-of-the-art unsupervised vehicle re-identification approaches.

cs.CV↗

GiT: Graph Interactive Transformer for Vehicle Re-identification

Transformers are more and more popular in computer vision, which treat an image as a sequence of patches and learn robust global features from the sequence. However, pure transformers are not entirely suitable for vehicle re-identification because vehicle re-identification requires both robust global features and discriminative local features. For that, a graph interactive transformer (GiT) is proposed in this paper. In the macro view, a list of GiT blocks are stacked to build a vehicle re-identification model, in where graphs are to extract discriminative local features within patches and transformers are to extract robust global features among patches. In the micro view, graphs and transformers are in an interactive status, bringing effective cooperation between local and global features. Specifically, one current graph is embedded after the former level's graph and transformer, while the current transform is embedded after the current graph and the former level's transformer. In addition to the interaction between graphs and transforms, the graph is a newly-designed local correction graph, which learns discriminative local features within a patch by exploring nodes' relationships. Extensive experiments on three large-scale vehicle re-identification datasets demonstrate that our GiT method is superior to state-of-the-art vehicle re-identification approaches.

cs.CV↗