Searcharxiv⌕ Search

arXiv subjects

François Rousseau

Publications and source records attributed to François Rousseau.

12 recordsLinked to original sources

Discovering Data Manifold Geometry through Geometric Properties

A prevailing paradigm in modern representation learning is the map-first approach, in which a representation map is learned from reconstruction, embedding, or task objectives. At the optimum, when the learned map accurately recovers a global coordinate chart, it should exhibit three structural properties whose geometric meaning can be illustrated through a face-editing example: Commutativity requires that changing pose and then expression gives the same result as applying them in the reverse order; Time Coherence requires that the same variation along one coordinate induces the same expression change across faces; Common-Reference requires that all faces are organized relative to a common reference face. However, small approximation errors in the learned map need not translate into small errors in these structural properties, and can therefore disrupt the global organization of the representation. Based on this observation, we consider the converse of the map-first formulation and ask whether a global representation can instead emerge by directly learning these properties. We represent variations along individual coordinates through vector fields defined in the ambient space and introduce a non-contraction condition preventing one transformation from destroying directions associated with the others. We derive an unsupervised objective that learns these structural properties and establish theoretical results connecting its minimization to tangent-space recovery. Experiments on controlled manifolds validate the predicted tangent-space recovery and global structure, while an autoencoder baseline shows that small map-first errors can still produce substantial violations of the targeted properties.

cs.LG↗

Majorization-Minimization Networks for Inverse Problems: An Application to EEG Imaging

Inverse problems are often ill-posed and require optimization schemes with strong stability and convergence guarantees. While learning-based approaches such as deep unrolling and meta-learning achieve strong empirical performance, they typically lack explicit control over descent and curvature, limiting robustness. We propose a learned Majorization-Minimization (MM) framework for inverse problems within a bilevel optimization setting. Instead of learning a full optimizer, we learn a structured curvature majorant that governs each MM step while preserving classical MM descent guarantees. The majorant is parameterized by a lightweight recurrent neural network and explicitly constrained to satisfy valid MM conditions. For cosine-similarity losses, we derive explicit curvature bounds yielding diagonal majorants. When analytic bounds are unavailable, we rely on efficient Hessian-vector product-based spectral estimation to automatically upper-bound local curvature without forming the Hessian explicitly. Experiments on EEG source imaging demonstrate improved accuracy, stability, and cross-dataset generalization over deep-unrolled and meta-learning baselines.

eess.SP↗

SIAM: Head and Brain MRI Segmentation from Few High-Quality Templates via Synthetic Training

Synthetic training has recently advanced brain MRI segmentation by enabling contrast-agnostic models trained entirely on generated data. However, most existing approaches rely on hundreds of automatically labeled templates, introducing systematic biases and limiting their flexibility to incorporate new anatomical structures. We present the Segment It All Model (SIAM), a 3D whole-head segmentation framework for 16 anatomical structures, trained using only six high-quality, manually annotated templates. SIAM extends domain randomization to both intensity and shape domains: synthetic image generation ensures contrast variability, while high-resolution spatial transformations model anatomical differences in cortical thickness and deep nuclei morphology. Unlike prior synthetic models, SIAM simultaneously segments brain as well as extra-cerebral tissues, including cerebrospinal fluid, vessels, dura mater, skull, and skin, enabling fully automated, preprocessing-free analysis. Evaluation across eight heterogeneous datasets (N=301), that include multiple contrasts (T1-weighted, T2-weighted, CT) and span a wide range of ages, demonstrates that SIAM matches or outperforms state-of-the-art methods for brain structures, in addition to extending automated segmentation to non-brain structures. The model also exhibits superior consistency across contrasts and repeated acquisitions, together with improved sensitivity to subtle gray matter atrophy. We openly release the model and the label templates at https://github.com/romainVala/SIAM.

cs.CV↗

The hidden sustainability bottleneck in high-entropy alloy design

Because of the enormous number of possible compositions, comparable to the number of stars in the universe, high-entropy alloys (HEAs) constitute a virtually inexhaustible materials space with highly versatile properties. Among these systems, HEAs are often proposed as potential substitutes for critical elements such as rare earths or platinum group metals. However, random or incremental exploration strategies are neither practical nor efficient at this scale. Targeted materials selection guided by sustainability considerations is therefore essential, yet identifying sustainable HEA compositions remains highly challenging. Here, we perform a comprehensive sustainability assessment of 30,201 equimolar HEA compositions and identify a resilient shortlist (approximately 5\%) that consistently exhibits favorable sustainability profiles across multiple evaluation schemes. Our analysis integrates complementary criteria including carbon footprint, environmental, social and governance (ESG) risks, production compatibility, and resource availability. The resulting sustainability-based ranking provides a strategic roadmap for HEA research, enabling experimental efforts to be focused on compositions that are not only functionally promising but also scalable and resource-responsible. By aligning materials discovery with sustainability and supply constraints, this framework supports more efficient use of experimental resources while contributing to long-term industrial sustainability goals.

physics.soc-ph↗

Fast and Explicit: Slice-to-Volume Reconstruction via 3D Gaussian Primitives with Analytic Point Spread Function Modeling

Recovering high-fidelity 3D images from sparse or degraded 2D images is a fundamental challenge in medical imaging, with broad applications ranging from 3D ultrasound reconstruction to MRI super-resolution. In the context of fetal MRI, high-resolution 3D reconstruction of the brain from motion-corrupted low-resolution 2D acquisitions is a prerequisite for accurate neurodevelopmental diagnosis. While implicit neural representations (INRs) have recently established state-of-the-art performance in self-supervised slice-to-volume reconstruction (SVR), they suffer from a critical computational bottleneck: accurately modeling the image acquisition physics requires expensive stochastic Monte Carlo sampling to approximate the point spread function (PSF). In this work, we propose a shift from neural network based implicit representations to Gaussian based explicit representations. By parameterizing the HR 3D image volume as a field of anisotropic Gaussian primitives, we leverage the property of Gaussians being closed under convolution and thus derive a \textit{closed-form analytical solution} for the forward model. This formulation reduces the previously intractable acquisition integral to an exact covariance addition ($\mathbfΣ_{obs} = \mathbfΣ_{HR} + \mathbfΣ_{PSF}$), effectively bypassing the need for compute-intensive stochastic sampling while ensuring exact gradient propagation. We demonstrate that our approach matches the reconstruction quality of self-supervised state-of-the-art SVR frameworks while delivering a 5$\times$--10$\times$ speed-up on neonatal and fetal data. With convergence often reached in under 30 seconds, our framework paves the way towards translation into clinical routine of real-time fetal 3D MRI. Code will be public at {https://github.com/m-dannecker/Gaussian-Primitives-for-Fast-SVR}.

cs.CV↗

Physics-Informed Joint Multi-TE Super-Resolution with Implicit Neural Representation for Robust Fetal T2 Mapping

T2 mapping in fetal brain MRI has the potential to improve characterization of the developing brain, especially at mid-field (0.55T), where T2 decay is slower. However, this is challenging as fetal MRI acquisition relies on multiple motion-corrupted stacks of thick slices, requiring slice-to-volume reconstruction (SVR) to estimate a high-resolution (HR) 3D volume. Currently, T2 mapping involves repeated acquisitions of these stacks at each echo time (TE), leading to long scan times and high sensitivity to motion. We tackle this challenge with a method that jointly reconstructs data across TEs, addressing severe motion. Our approach combines implicit neural representations with a physics-informed regularization that models T2 decay, enabling information sharing across TEs while preserving anatomical and quantitative T2 fidelity. We demonstrate state-of-the-art performance on simulated fetal brain and in vivo adult datasets with fetal-like motion. We also present the first in vivo fetal T2 mapping results at 0.55T. Our study shows potential for reducing the number of stacks per TE in T2 mapping by leveraging anatomical redundancy.

cs.CV↗

Turning Normalizing Flows into Monge Maps with Geodesic Gaussian Preserving Flows

Normalizing Flows (NF) are powerful likelihood-based generative models that are able to trade off between expressivity and tractability to model complex densities. A now well established research avenue leverages optimal transport (OT) and looks for Monge maps, i.e. models with minimal effort between the source and target distributions. This paper introduces a method based on Brenier's polar factorization theorem to transform any trained NF into a more OT-efficient version without changing the final density. We do so by learning a rearrangement of the source (Gaussian) distribution that minimizes the OT cost between the source and the final density. We further constrain the path leading to the estimated Monge map to lie on a geodesic in the space of volume-preserving diffeomorphisms thanks to Euler's equations. The proposed method leads to smooth flows with reduced OT cost for several existing models without affecting the model performance.

cs.LG↗

Gradients of Connectivity as Graph Fourier Bases of Brain Activity

The application of graph theory to model the complex structure and function of the brain has shed new light on its organization and function, prompting the emergence of network neuroscience. Despite the tremendous progress that has been achieved in this field, still relatively few methods exploit the topology of brain networks to analyze brain activity. Recent attempts in this direction have leveraged on graph spectral analysis and graph signal processing to decompose brain activity in connectivity eigenmodes or gradients. If results are promising in terms of interpretability and functional relevance, methodologies and terminology are sometimes confusing. The goals of this paper are twofold. First, we summarize recent contributions related to connectivity gradients and graph signal processing, and attempt a clarification of the terminology and methods used in the field, while pointing out current methodological limitations. Second, we discuss the perspective that the functional relevance of connectivity gradients could be fruitfully exploited by considering them as graph Fourier bases of brain activity.

eess.SP↗

Abdominal multi-organ segmentation with cascaded convolutional and adversarial deep networks

Objective : Abdominal anatomy segmentation is crucial for numerous applications from computer-assisted diagnosis to image-guided surgery. In this context, we address fully-automated multi-organ segmentation from abdominal CT and MR images using deep learning. Methods: The proposed model extends standard conditional generative adversarial networks. Additionally to the discriminator which enforces the model to create realistic organ delineations, it embeds cascaded partially pre-trained convolutional encoder-decoders as generator. Encoder fine-tuning from a large amount of non-medical images alleviates data scarcity limitations. The network is trained end-to-end to benefit from simultaneous multi-level segmentation refinements using auto-context. Results : Employed for healthy liver, kidneys and spleen segmentation, our pipeline provides promising results by outperforming state-of-the-art encoder-decoder schemes. Followed for the Combined Healthy Abdominal Organ Segmentation (CHAOS) challenge organized in conjunction with the IEEE International Symposium on Biomedical Imaging 2019, it gave us the first rank for three competition categories: liver CT, liver MR and multi-organ MR segmentation. Conclusion : Combining cascaded convolutional and adversarial networks strengthens the ability of deep learning pipelines to automatically delineate multiple abdominal organs, with good generalization capability. Significance : The comprehensive evaluation provided suggests that better guidance could be achieved to help clinicians in abdominal image interpretation and clinical decision making.

eess.IV↗

End-to-end learning of energy-based representations for irregularly-sampled signals and images

For numerous domains, including for instance earth observation, medical imaging, astrophysics,..., available image and signal datasets often involve irregular space-time sampling patterns and large missing data rates. These sampling properties may be critical to apply state-of-the-art learning-based (e.g., auto-encoders, CNNs,...), fully benefit from the available large-scale observations and reach breakthroughs in the reconstruction and identification of processes of interest. In this paper, we address the end-to-end learning of representations of signals, images and image sequences from irregularly-sampled data, i.e. when the training data involved missing data. From an analogy to Bayesian formulation, we consider energy-based representations. Two energy forms are investigated: one derived from auto-encoders and one relating to Gibbs priors. The learning stage of these energy-based representations (or priors) involve a joint interpolation issue, which amounts to solving an energy minimization problem under observation constraints. Using a neural-network-based implementation of the considered energy forms, we can state an end-to-end learning scheme from irregularly-sampled data. We demonstrate the relevance of the proposed representations for different case-studies: namely, multivariate time series, 2D images and image sequences.

cs.CV↗

Global Perturbation of Initial Geometry in a Biomechanical Model of Cortical Morphogenesis

Cortical folding pattern is a main characteristic of the geometry of the human brain which is formed by gyri (ridges) and sulci (grooves). Several biological hypotheses have suggested different mechanisms that attempt to explain the development of cortical folding and its abnormal evolutions. Based on these hypotheses, biomechanical models of cortical folding have been proposed. In this work, we compare biomechanical simulations for several initial conditions by using an adaptive spherical parameterization approach. Our approach allows us to study and explore one of the most potential sources of reproducible cortical folding pattern: the specification of initial geometry of the brain.

physics.bio-ph↗

On early brain folding patterns using biomechanical growth modeling

Abnormal cortical folding patterns may be related to neurodevelopmental disorders such as lissencephaly and polymicrogyria. In this context, computational modeling is a powerful tool to provide a better understanding of the early brain folding process. Recent studies based on biomechanical modeling have shown that mechanical forces play a crucial role in the formation of cortical convolutions. However, the correlation between simulation results and biological facts, and the effect of physical parameters in these models remain unclear. In this paper, we propose a new brain longitudinal length growth model to improve brain model growth. In addition, we investigate the effect of the initial cortical thickness on folding patterns, quantifying the folds by the surface-based three-dimensional gyrification index and a spectral analysis of gyrification. The results tend to show that the use of such biomechanical models could highlight the links between neurodevelopmental diseases and physical parameters.

physics.med-ph↗