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Gordon Wetzstein

Publications and source records attributed to Gordon Wetzstein.

At least 55 records · Page 3Linked to original sources

Multiscale guidance of protein structure prediction with heterogeneous cryo-EM data

Protein structure prediction models are now capable of generating accurate 3D structural hypotheses from sequence alone. However, they routinely fail to capture the conformational diversity of dynamic biomolecular complexes, often requiring heuristic MSA subsampling approaches for generating alternative states. In parallel, cryo-electron microscopy (cryo-EM) has emerged as a powerful tool for imaging near-native structural heterogeneity, but is challenged by arduous pipelines to transform raw experimental data into atomic models. Here, we bridge the gap between these modalities, combining cryo-EM density maps with the rich sequence and biophysical priors learned by protein structure prediction models. Our method, CryoBoltz, guides the sampling trajectory of a pretrained biomolecular structure prediction model using both global and local structural constraints derived from density maps, driving predictions towards conformational states consistent with the experimental data. We demonstrate that this flexible yet powerful inference-time approach allows us to build atomic models into heterogeneous cryo-EM maps across a variety of dynamic biomolecular systems including transporters and antibodies. Code is available at https://github.com/ml-struct-bio/cryoboltz .

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WonderPlay: Dynamic 3D Scene Generation from a Single Image and Actions

WonderPlay is a novel framework integrating physics simulation with video generation for generating action-conditioned dynamic 3D scenes from a single image. While prior works are restricted to rigid body or simple elastic dynamics, WonderPlay features a hybrid generative simulator to synthesize a wide range of 3D dynamics. The hybrid generative simulator first uses a physics solver to simulate coarse 3D dynamics, which subsequently conditions a video generator to produce a video with finer, more realistic motion. The generated video is then used to update the simulated dynamic 3D scene, closing the loop between the physics solver and the video generator. This approach enables intuitive user control to be combined with the accurate dynamics of physics-based simulators and the expressivity of diffusion-based video generators. Experimental results demonstrate that WonderPlay enables users to interact with various scenes of diverse content, including cloth, sand, snow, liquid, smoke, elastic, and rigid bodies -- all using a single image input. Code will be made public. Project website: https://kyleleey.github.io/WonderPlay/

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CL-Splats: Continual Learning of Gaussian Splatting with Local Optimization

In dynamic 3D environments, accurately updating scene representations over time is crucial for applications in robotics, mixed reality, and embodied AI. As scenes evolve, efficient methods to incorporate changes are needed to maintain up-to-date, high-quality reconstructions without the computational overhead of re-optimizing the entire scene. This paper introduces CL-Splats, which incrementally updates Gaussian splatting-based 3D representations from sparse scene captures. CL-Splats integrates a robust change-detection module that segments updated and static components within the scene, enabling focused, local optimization that avoids unnecessary re-computation. Moreover, CL-Splats supports storing and recovering previous scene states, facilitating temporal segmentation and new scene-analysis applications. Our extensive experiments demonstrate that CL-Splats achieves efficient updates with improved reconstruction quality over the state-of-the-art. This establishes a robust foundation for future real-time adaptation in 3D scene reconstruction tasks.

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Frame Context Packing and Drift Prevention in Next-Frame-Prediction Video Diffusion Models

We present a neural network structure, FramePack, to train next-frame (or next-frame-section) prediction models for video generation. FramePack compresses input frame contexts with frame-wise importance so that more frames can be encoded within a fixed context length, with more important frames having longer contexts. The frame importance can be measured using time proximity, feature similarity, or hybrid metrics. The packing method allows for inference with thousands of frames and training with relatively large batch sizes. We also present drift prevention methods to address observation bias (error accumulation), including early-established endpoints, adjusted sampling orders, and discrete history representation. Ablation studies validate the effectiveness of the anti-drifting methods in both single-directional video streaming and bi-directional video generation. Finally, we show that existing video diffusion models can be finetuned with FramePack, and analyze the differences between different packing schedules.

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Taming Flow-based I2V Models for Creative Video Editing

Although image editing techniques have advanced significantly, video editing, which aims to manipulate videos according to user intent, remains an emerging challenge. Most existing image-conditioned video editing methods either require inversion with model-specific design or need extensive optimization, limiting their capability of leveraging up-to-date image-to-video (I2V) models to transfer the editing capability of image editing models to the video domain. To this end, we propose IF-V2V, an Inversion-Free method that can adapt off-the-shelf flow-matching-based I2V models for video editing without significant computational overhead. To circumvent inversion, we devise Vector Field Rectification with Sample Deviation to incorporate information from the source video into the denoising process by introducing a deviation term into the denoising vector field. To further ensure consistency with the source video in a model-agnostic way, we introduce Structure-and-Motion-Preserving Initialization to generate motion-aware temporally correlated noise with structural information embedded. We also present a Deviation Caching mechanism to minimize the additional computational cost for denoising vector rectification without significantly impacting editing quality. Evaluations demonstrate that our method achieves superior editing quality and consistency over existing approaches, offering a lightweight plug-and-play solution to realize visual creativity.

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Visual Chronicles: Using Multimodal LLMs to Analyze Massive Collections of Images

We present a system using Multimodal LLMs (MLLMs) to analyze a large database with tens of millions of images captured at different times, with the aim of discovering patterns in temporal changes. Specifically, we aim to capture frequent co-occurring changes ("trends") across a city over a certain period. Unlike previous visual analyses, our analysis answers open-ended queries (e.g., "what are the frequent types of changes in the city?") without any predetermined target subjects or training labels. These properties cast prior learning-based or unsupervised visual analysis tools unsuitable. We identify MLLMs as a novel tool for their open-ended semantic understanding capabilities. Yet, our datasets are four orders of magnitude too large for an MLLM to ingest as context. So we introduce a bottom-up procedure that decomposes the massive visual analysis problem into more tractable sub-problems. We carefully design MLLM-based solutions to each sub-problem. During experiments and ablation studies with our system, we find it significantly outperforms baselines and is able to discover interesting trends from images captured in large cities (e.g., "addition of outdoor dining,", "overpass was painted blue," etc.). See more results and interactive demos at https://boyangdeng.com/visual-chronicles.

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Gaussian Mixture Flow Matching Models

Diffusion models approximate the denoising distribution as a Gaussian and predict its mean, whereas flow matching models reparameterize the Gaussian mean as flow velocity. However, they underperform in few-step sampling due to discretization error and tend to produce over-saturated colors under classifier-free guidance (CFG). To address these limitations, we propose a novel Gaussian mixture flow matching (GMFlow) model: instead of predicting the mean, GMFlow predicts dynamic Gaussian mixture (GM) parameters to capture a multi-modal flow velocity distribution, which can be learned with a KL divergence loss. We demonstrate that GMFlow generalizes previous diffusion and flow matching models where a single Gaussian is learned with an $L_2$ denoising loss. For inference, we derive GM-SDE/ODE solvers that leverage analytic denoising distributions and velocity fields for precise few-step sampling. Furthermore, we introduce a novel probabilistic guidance scheme that mitigates the over-saturation issues of CFG and improves image generation quality. Extensive experiments demonstrate that GMFlow consistently outperforms flow matching baselines in generation quality, achieving a Precision of 0.942 with only 6 sampling steps on ImageNet 256$\times$256.

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3DGen-Bench: Comprehensive Benchmark Suite for 3D Generative Models

3D generation is experiencing rapid advancements, while the development of 3D evaluation has not kept pace. How to keep automatic evaluation equitably aligned with human perception has become a well-recognized challenge. Recent advances in the field of language and image generation have explored human preferences and showcased respectable fitting ability. However, the 3D domain still lacks such a comprehensive preference dataset over generative models. To mitigate this absence, we develop 3DGen-Arena, an integrated platform in a battle manner. Then, we carefully design diverse text and image prompts and leverage the arena platform to gather human preferences from both public users and expert annotators, resulting in a large-scale multi-dimension human preference dataset 3DGen-Bench. Using this dataset, we further train a CLIP-based scoring model, 3DGen-Score, and a MLLM-based automatic evaluator, 3DGen-Eval. These two models innovatively unify the quality evaluation of text-to-3D and image-to-3D generation, and jointly form our automated evaluation system with their respective strengths. Extensive experiments demonstrate the efficacy of our scoring model in predicting human preferences, exhibiting a superior correlation with human ranks compared to existing metrics. We believe that our 3DGen-Bench dataset and automated evaluation system will foster a more equitable evaluation in the field of 3D generation, further promoting the development of 3D generative models and their downstream applications. Project page is available at https://zyh482.github.io/3DGen-Bench/.

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Captain Cinema: Towards Short Movie Generation

We present Captain Cinema, a generation framework for short movie generation. Given a detailed textual description of a movie storyline, our approach firstly generates a sequence of keyframes that outline the entire narrative, which ensures long-range coherence in both the storyline and visual appearance (e.g., scenes and characters). We refer to this step as top-down keyframe planning. These keyframes then serve as conditioning signals for a video synthesis model, which supports long context learning, to produce the spatio-temporal dynamics between them. This step is referred to as bottom-up video synthesis. To support stable and efficient generation of multi-scene long narrative cinematic works, we introduce an interleaved training strategy for Multimodal Diffusion Transformers (MM-DiT), specifically adapted for long-context video data. Our model is trained on a specially curated cinematic dataset consisting of interleaved data pairs. Our experiments demonstrate that Captain Cinema performs favorably in the automated creation of visually coherent and narrative consistent short movies in high quality and efficiency. Project page: https://thecinema.ai

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Towards Vision-Language-Garment Models for Web Knowledge Garment Understanding and Generation

Multimodal foundation models have demonstrated strong generalization, yet their ability to transfer knowledge to specialized domains such as garment generation remains underexplored. We introduce VLG, a vision-language-garment model that synthesizes garments from textual descriptions and visual imagery. Our experiments assess VLG's zero-shot generalization, investigating its ability to transfer web-scale reasoning to unseen garment styles and prompts. Preliminary results indicate promising transfer capabilities, highlighting the potential for multimodal foundation models to adapt effectively to specialized domains like fashion design.

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ByteMorph: Benchmarking Instruction-Guided Image Editing with Non-Rigid Motions

Editing images with instructions to reflect non-rigid motions, camera viewpoint shifts, object deformations, human articulations, and complex interactions, poses a challenging yet underexplored problem in computer vision. Existing approaches and datasets predominantly focus on static scenes or rigid transformations, limiting their capacity to handle expressive edits involving dynamic motion. To address this gap, we introduce ByteMorph, a comprehensive framework for instruction-based image editing with an emphasis on non-rigid motions. ByteMorph comprises a large-scale dataset, ByteMorph-6M, and a strong baseline model built upon the Diffusion Transformer (DiT), named ByteMorpher. ByteMorph-6M includes over 6 million high-resolution image editing pairs for training, along with a carefully curated evaluation benchmark ByteMorph-Bench. Both capture a wide variety of non-rigid motion types across diverse environments, human figures, and object categories. The dataset is constructed using motion-guided data generation, layered compositing techniques, and automated captioning to ensure diversity, realism, and semantic coherence. We further conduct a comprehensive evaluation of recent instruction-based image editing methods from both academic and commercial domains.

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Video World Models with Long-term Spatial Memory

Emerging world models autoregressively generate video frames in response to actions, such as camera movements and text prompts, among other control signals. Due to limited temporal context window sizes, these models often struggle to maintain scene consistency during revisits, leading to severe forgetting of previously generated environments. Inspired by the mechanisms of human memory, we introduce a novel framework to enhancing long-term consistency of video world models through a geometry-grounded long-term spatial memory. Our framework includes mechanisms to store and retrieve information from the long-term spatial memory and we curate custom datasets to train and evaluate world models with explicitly stored 3D memory mechanisms. Our evaluations show improved quality, consistency, and context length compared to relevant baselines, paving the way towards long-term consistent world generation.

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Textured Gaussians for Enhanced 3D Scene Appearance Modeling

3D Gaussian Splatting (3DGS) has recently emerged as a state-of-the-art 3D reconstruction and rendering technique due to its high-quality results and fast training and rendering time. However, pixels covered by the same Gaussian are always shaded in the same color up to a Gaussian falloff scaling factor. Furthermore, the finest geometric detail any individual Gaussian can represent is a simple ellipsoid. These properties of 3DGS greatly limit the expressivity of individual Gaussian primitives. To address these issues, we draw inspiration from texture and alpha mapping in traditional graphics and integrate it with 3DGS. Specifically, we propose a new generalized Gaussian appearance representation that augments each Gaussian with alpha~(A), RGB, or RGBA texture maps to model spatially varying color and opacity across the extent of each Gaussian. As such, each Gaussian can represent a richer set of texture patterns and geometric structures, instead of just a single color and ellipsoid as in naive Gaussian Splatting. Surprisingly, we found that the expressivity of Gaussians can be greatly improved by using alpha-only texture maps, and further augmenting Gaussians with RGB texture maps achieves the highest expressivity. We validate our method on a wide variety of standard benchmark datasets and our own custom captures at both the object and scene levels. We demonstrate image quality improvements over existing methods while using a similar or lower number of Gaussians.

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Long-Context State-Space Video World Models

Video diffusion models have recently shown promise for world modeling through autoregressive frame prediction conditioned on actions. However, they struggle to maintain long-term memory due to the high computational cost associated with processing extended sequences in attention layers. To overcome this limitation, we propose a novel architecture leveraging state-space models (SSMs) to extend temporal memory without compromising computational efficiency. Unlike previous approaches that retrofit SSMs for non-causal vision tasks, our method fully exploits the inherent advantages of SSMs in causal sequence modeling. Central to our design is a block-wise SSM scanning scheme, which strategically trades off spatial consistency for extended temporal memory, combined with dense local attention to ensure coherence between consecutive frames. We evaluate the long-term memory capabilities of our model through spatial retrieval and reasoning tasks over extended horizons. Experiments on Memory Maze and Minecraft datasets demonstrate that our approach surpasses baselines in preserving long-range memory, while maintaining practical inference speeds suitable for interactive applications.

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Interspatial Attention for Efficient 4D Human Video Generation

Generating photorealistic videos of digital humans in a controllable manner is crucial for a plethora of applications. Existing approaches either build on methods that employ template-based 3D representations or emerging video generation models but suffer from poor quality or limited consistency and identity preservation when generating individual or multiple digital humans. In this paper, we introduce a new interspatial attention (ISA) mechanism as a scalable building block for modern diffusion transformer (DiT)--based video generation models. ISA is a new type of cross attention that uses relative positional encodings tailored for the generation of human videos. Leveraging a custom-developed video variation autoencoder, we train a latent ISA-based diffusion model on a large corpus of video data. Our model achieves state-of-the-art performance for 4D human video synthesis, demonstrating remarkable motion consistency and identity preservation while providing precise control of the camera and body poses. Our code and model are publicly released at https://dsaurus.github.io/isa4d/.

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Gaussian Wave Splatting for Computer-Generated Holography

State-of-the-art neural rendering methods optimize Gaussian scene representations from a few photographs for novel-view synthesis. Building on these representations, we develop an efficient algorithm, dubbed Gaussian Wave Splatting, to turn these Gaussians into holograms. Unlike existing computer-generated holography (CGH) algorithms, Gaussian Wave Splatting supports accurate occlusions and view-dependent effects for photorealistic scenes by leveraging recent advances in neural rendering. Specifically, we derive a closed-form solution for a 2D Gaussian-to-hologram transform that supports occlusions and alpha blending. Inspired by classic computer graphics techniques, we also derive an efficient approximation of the aforementioned process in the Fourier domain that is easily parallelizable and implement it using custom CUDA kernels. By integrating emerging neural rendering pipelines with holographic display technology, our Gaussian-based CGH framework paves the way for next-generation holographic displays.

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R-Bench: Graduate-level Multi-disciplinary Benchmarks for LLM & MLLM Complex Reasoning Evaluation

Reasoning stands as a cornerstone of intelligence, enabling the synthesis of existing knowledge to solve complex problems. Despite remarkable progress, existing reasoning benchmarks often fail to rigorously evaluate the nuanced reasoning capabilities required for complex, real-world problemsolving, particularly in multi-disciplinary and multimodal contexts. In this paper, we introduce a graduate-level, multi-disciplinary, EnglishChinese benchmark, dubbed as Reasoning Bench (R-Bench), for assessing the reasoning capability of both language and multimodal models. RBench spans 1,094 questions across 108 subjects for language model evaluation and 665 questions across 83 subjects for multimodal model testing in both English and Chinese. These questions are meticulously curated to ensure rigorous difficulty calibration, subject balance, and crosslinguistic alignment, enabling the assessment to be an Olympiad-level multi-disciplinary benchmark. We evaluate widely used models, including OpenAI o1, GPT-4o, DeepSeek-R1, etc. Experimental results indicate that advanced models perform poorly on complex reasoning, especially multimodal reasoning. Even the top-performing model OpenAI o1 achieves only 53.2% accuracy on our multimodal evaluation. Data and code are made publicly available at here.

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ReStyle3D: Scene-Level Appearance Transfer with Semantic Correspondences

We introduce ReStyle3D, a novel framework for scene-level appearance transfer from a single style image to a real-world scene represented by multiple views. The method combines explicit semantic correspondences with multi-view consistency to achieve precise and coherent stylization. Unlike conventional stylization methods that apply a reference style globally, ReStyle3D uses open-vocabulary segmentation to establish dense, instance-level correspondences between the style and real-world images. This ensures that each object is stylized with semantically matched textures. It first transfers the style to a single view using a training-free semantic-attention mechanism in a diffusion model. It then lifts the stylization to additional views via a learned warp-and-refine network guided by monocular depth and pixel-wise correspondences. Experiments show that ReStyle3D consistently outperforms prior methods in structure preservation, perceptual style similarity, and multi-view coherence. User studies further validate its ability to produce photo-realistic, semantically faithful results. Our code, pretrained models, and dataset will be publicly released, to support new applications in interior design, virtual staging, and 3D-consistent stylization.

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