arXiv subjects

Gustavo Carneiro

Publications and source records attributed to Gustavo Carneiro.

At least 37 records · Page 2Linked to original sources

arXiv2025

Maximising the Utility of Validation Sets for Imbalanced Noisy-label Meta-learning

Meta-learning is an effective method to handle imbalanced and noisy-label learning, but it depends on a validation set containing randomly selected, manually labelled and balanced distributed samples. The random selection and manual labelling and balancing of this validation set is not only sub-optimal for meta-learning, but it also scales poorly with the number of classes. Hence, recent meta-learning papers have proposed ad-hoc heuristics to automatically build and label this validation set, but these heuristics are still sub-optimal for meta-learning. In this paper, we analyse the meta-learning algorithm and propose new criteria to characterise the utility of the validation set, based on: 1) the informativeness of the validation set; 2) the class distribution balance of the set; and 3) the correctness of the labels of the set. Furthermore, we propose a new imbalanced noisy-label meta-learning (INOLML) algorithm that automatically builds a validation set by maximising its utility using the criteria above. Our method shows significant improvements over previous meta-learning approaches and sets the new state-of-the-art on several benchmarks.

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arXiv2025

Towards the Identifiability in Noisy Label Learning: A Multinomial Mixture Modelling Approach

Learning from noisy labels (LNL) is crucial in deep learning, in which one of the approaches is to identify clean-label samples from poorly-annotated datasets. Such an identification is challenging because the conventional LNL problem, which assumes only one noisy label per instance, is non-identifiable, i.e., clean labels cannot be estimated theoretically without additional heuristics. This paper presents a novel data-driven approach that addresses this issue without requiring any heuristics about clean samples. We discover that the LNL problem becomes identifiable if there are at least $2C - 1$ i.i.d. noisy labels per instance, where $C$ is the number of classes. Our finding relies on the assumption of i.i.d. noisy labels and multinomial mixture modelling, making it easier to interpret than previous studies that require full-rank noisy-label transition matrices. To fulfil this condition without additional manual annotations, we propose a method that automatically generates additional i.i.d. noisy labels through nearest neighbours. These noisy labels are then used in the Expectation-Maximisation algorithm to infer clean labels. Our method demonstrably estimates clean labels accurately across various label noise benchmarks, including synthetic, web-controlled, and real-world datasets. Furthermore, the model trained with our method performs competitively with many state-of-the-art methods.

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arXiv2025

Meta-Learned Modality-Weighted Knowledge Distillation for Robust Multi-Modal Learning with Missing Data

In multi-modal learning, some modalities are more influential than others, and their absence can have a significant impact on classification/segmentation accuracy. Addressing this challenge, we propose a novel approach called Meta-learned Modality-weighted Knowledge Distillation (MetaKD), which enables multi-modal models to maintain high accuracy even when key modalities are missing. MetaKD adaptively estimates the importance weight of each modality through a meta-learning process. These learned importance weights guide a pairwise modality-weighted knowledge distillation process, allowing high-importance modalities to transfer knowledge to lower-importance ones, resulting in robust performance despite missing inputs. Unlike previous methods in the field, which are often task-specific and require significant modifications, our approach is designed to work in multiple tasks (e.g., segmentation and classification) with minimal adaptation. Experimental results on five prevalent datasets, including three Brain Tumor Segmentation datasets (BraTS2018, BraTS2019 and BraTS2020), the Alzheimer's Disease Neuroimaging Initiative (ADNI) classification dataset and the Audiovision-MNIST classification dataset, demonstrate the proposed model is able to outperform the compared models by a large margin. The code is available at https://github.com/billhhh/MetaKD.

cs.CV↗

arXiv2025

Risk Estimation of Knee Osteoarthritis Progression via Predictive Multi-task Modelling from Efficient Diffusion Model using X-ray Images

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease progression) and predictive modelling (i.e., the forecasting of future outcomes based on current data) using medical images, but clinical adoption remains limited due to their lack of interpretability. Existing approaches that generate future images for risk estimation are complex and impractical. Additionally, previous methods fail to localize anatomical knee landmarks, limiting interpretability. We address these gaps with a new interpretable machine learning method to estimate the risk of knee OA progression via multi-task predictive modelling that classifies future knee OA severity and predicts anatomical knee landmarks from efficiently generated high-quality future images. Such image generation is achieved by leveraging a diffusion model in a class-conditioned latent space to forecast disease progression, offering a visual representation of how particular health conditions may evolve. Applied to the Osteoarthritis Initiative dataset, our approach improves the state-of-the-art (SOTA) by 2\%, achieving an AUC of 0.71 in predicting knee OA progression while offering ~9% faster inference time.

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arXiv2025

Translation Consistent Semi-supervised Segmentation for 3D Medical Images

3D medical image segmentation methods have been successful, but their dependence on large amounts of voxel-level annotated data is a disadvantage that needs to be addressed given the high cost to obtain such annotation. Semi-supervised learning (SSL) solve this issue by training models with a large unlabelled and a small labelled dataset. The most successful SSL approaches are based on consistency learning that minimises the distance between model responses obtained from perturbed views of the unlabelled data. These perturbations usually keep the spatial input context between views fairly consistent, which may cause the model to learn segmentation patterns from the spatial input contexts instead of the segmented objects. In this paper, we introduce the Translation Consistent Co-training (TraCoCo) which is a consistency learning SSL method that perturbs the input data views by varying their spatial input context, allowing the model to learn segmentation patterns from visual objects. Furthermore, we propose the replacement of the commonly used mean squared error (MSE) semi-supervised loss by a new Cross-model confident Binary Cross entropy (CBC) loss, which improves training convergence and keeps the robustness to co-training pseudo-labelling mistakes. We also extend CutMix augmentation to 3D SSL to further improve generalisation. Our TraCoCo shows state-of-the-art results for the Left Atrium (LA) and Brain Tumor Segmentation (BRaTS19) datasets with different backbones. Our code is available at https://github.com/yyliu01/TraCoCo.

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arXiv2025

ItTakesTwo: Leveraging Peer Representations for Semi-supervised LiDAR Semantic Segmentation

The costly and time-consuming annotation process to produce large training sets for modelling semantic LiDAR segmentation methods has motivated the development of semi-supervised learning (SSL) methods. However, such SSL approaches often concentrate on employing consistency learning only for individual LiDAR representations. This narrow focus results in limited perturbations that generally fail to enable effective consistency learning. Additionally, these SSL approaches employ contrastive learning based on the sampling from a limited set of positive and negative embedding samples. This paper introduces a novel semi-supervised LiDAR semantic segmentation framework called ItTakesTwo (IT2). IT2 is designed to ensure consistent predictions from peer LiDAR representations, thereby improving the perturbation effectiveness in consistency learning. Furthermore, our contrastive learning employs informative samples drawn from a distribution of positive and negative embeddings learned from the entire training set. Results on public benchmarks show that our approach achieves remarkable improvements over the previous state-of-the-art (SOTA) methods in the field. The code is available at: https://github.com/yyliu01/IT2.

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arXiv2025

Mixture of Gaussian-distributed Prototypes with Generative Modelling for Interpretable and Trustworthy Image Recognition

Prototypical-part methods, e.g., ProtoPNet, enhance interpretability in image recognition by linking predictions to training prototypes, thereby offering intuitive insights into their decision-making. Existing methods, which rely on a point-based learning of prototypes, typically face two critical issues: 1) the learned prototypes have limited representation power and are not suitable to detect Out-of-Distribution (OoD) inputs, reducing their decision trustworthiness; and 2) the necessary projection of the learned prototypes back into the space of training images causes a drastic degradation in the predictive performance. Furthermore, current prototype learning adopts an aggressive approach that considers only the most active object parts during training, while overlooking sub-salient object regions which still hold crucial classification information. In this paper, we present a new generative paradigm to learn prototype distributions, termed as Mixture of Gaussian-distributed Prototypes (MGProto). The distribution of prototypes from MGProto enables both interpretable image classification and trustworthy recognition of OoD inputs. The optimisation of MGProto naturally projects the learned prototype distributions back into the training image space, thereby addressing the performance degradation caused by prototype projection. Additionally, we develop a novel and effective prototype mining strategy that considers not only the most active but also sub-salient object parts. To promote model compactness, we further propose to prune MGProto by removing prototypes with low importance priors. Experiments on CUB-200-2011, Stanford Cars, Stanford Dogs, and Oxford-IIIT Pets datasets show that MGProto achieves state-of-the-art image recognition and OoD detection performances, while providing encouraging interpretability results.

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arXiv2025

Cross- and Intra-image Prototypical Learning for Multi-label Disease Diagnosis and Interpretation

Recent advances in prototypical learning have shown remarkable potential to provide useful decision interpretations associating activation maps and predictions with class-specific training prototypes. Such prototypical learning has been well-studied for various single-label diseases, but for quite relevant and more challenging multi-label diagnosis, where multiple diseases are often concurrent within an image, existing prototypical learning models struggle to obtain meaningful activation maps and effective class prototypes due to the entanglement of the multiple diseases. In this paper, we present a novel Cross- and Intra-image Prototypical Learning (CIPL) framework, for accurate multi-label disease diagnosis and interpretation from medical images. CIPL takes advantage of common cross-image semantics to disentangle the multiple diseases when learning the prototypes, allowing a comprehensive understanding of complicated pathological lesions. Furthermore, we propose a new two-level alignment-based regularisation strategy that effectively leverages consistent intra-image information to enhance interpretation robustness and predictive performance. Extensive experiments show that our CIPL attains the state-of-the-art (SOTA) classification accuracy in two public multi-label benchmarks of disease diagnosis: thoracic radiography and fundus images. Quantitative interpretability results show that CIPL also has superiority in weakly-supervised thoracic disease localisation over other leading saliency- and prototype-based explanation methods.

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arXiv2025

AI-Powered Prediction of Nanoparticle Pharmacokinetics: A Multi-View Learning Approach

The clinical translation of nanoparticle-based treatments remains limited due to the unpredictability of (nanoparticle) NP pharmacokinetics$\unicode{x2014}$how they distribute, accumulate, and clear from the body. Predicting these behaviours is challenging due to complex biological interactions and the difficulty of obtaining high-quality experimental datasets. Existing AI-driven approaches rely heavily on data-driven learning but fail to integrate crucial knowledge about NP properties and biodistribution mechanisms. We introduce a multi-view deep learning framework that enhances pharmacokinetic predictions by incorporating prior knowledge of key NP properties such as size and charge into a cross-attention mechanism, enabling context-aware feature selection and improving generalization despite small datasets. To further enhance prediction robustness, we employ an ensemble learning approach, combining deep learning with XGBoost (XGB) and Random Forest (RF), which significantly outperforms existing AI models. Our interpretability analysis reveals key physicochemical properties driving NP biodistribution, providing biologically meaningful insights into possible mechanisms governing NP behaviour in vivo rather than a black-box model. Furthermore, by bridging machine learning with physiologically based pharmacokinetic (PBPK) modelling, this work lays the foundation for data-efficient AI-driven drug discovery and precision nanomedicine.

cs.LG↗

arXiv2025

Toward a Human-Centered AI-assisted Colonoscopy System in Australia

While AI-assisted colonoscopy promises improved colorectal cancer screening, its success relies on effective integration into clinical practice, not just algorithmic accuracy. This paper, based on an Australian field study (observations and gastroenterologist interviews), highlights a critical disconnect: current development prioritizes machine learning model performance, overlooking essential aspects of user interface design, workflow integration, and overall user experience. Industry interactions reveal a similar emphasis on data and algorithms. To realize AI's full potential, the HCI community must champion user-centered design, ensuring these systems are usable, support endoscopist expertise, and enhance patient outcomes.

cs.HC↗

arXiv2025

Learnable Cross-modal Knowledge Distillation for Multi-modal Learning with Missing Modality

The problem of missing modalities is both critical and non-trivial to be handled in multi-modal models. It is common for multi-modal tasks that certain modalities contribute more compared to other modalities, and if those important modalities are missing, the model performance drops significantly. Such fact remains unexplored by current multi-modal approaches that recover the representation from missing modalities by feature reconstruction or blind feature aggregation from other modalities, instead of extracting useful information from the best performing modalities. In this paper, we propose a Learnable Cross-modal Knowledge Distillation (LCKD) model to adaptively identify important modalities and distil knowledge from them to help other modalities from the cross-modal perspective for solving the missing modality issue. Our approach introduces a teacher election procedure to select the most ``qualified'' teachers based on their single modality performance on certain tasks. Then, cross-modal knowledge distillation is performed between teacher and student modalities for each task to push the model parameters to a point that is beneficial for all tasks. Hence, even if the teacher modalities for certain tasks are missing during testing, the available student modalities can accomplish the task well enough based on the learned knowledge from their automatically elected teacher modalities. Experiments on the Brain Tumour Segmentation Dataset 2018 (BraTS2018) shows that LCKD outperforms other methods by a considerable margin, improving the state-of-the-art performance by 3.61% for enhancing tumour, 5.99% for tumour core, and 3.76% for whole tumour in terms of segmentation Dice score.

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arXiv2025

Set a Thief to Catch a Thief: Combating Label Noise through Noisy Meta Learning

Learning from noisy labels (LNL) aims to train high-performance deep models using noisy datasets. Meta learning based label correction methods have demonstrated remarkable performance in LNL by designing various meta label rectification tasks. However, extra clean validation set is a prerequisite for these methods to perform label correction, requiring extra labor and greatly limiting their practicality. To tackle this issue, we propose a novel noisy meta label correction framework STCT, which counterintuitively uses noisy data to correct label noise, borrowing the spirit in the saying ``Set a Thief to Catch a Thief''. The core idea of STCT is to leverage noisy data which is i.i.d. with the training data as a validation set to evaluate model performance and perform label correction in a meta learning framework, eliminating the need for extra clean data. By decoupling the complex bi-level optimization in meta learning into representation learning and label correction, STCT is solved through an alternating training strategy between noisy meta correction and semi-supervised representation learning. Extensive experiments on synthetic and real-world datasets demonstrate the outstanding performance of STCT, particularly in high noise rate scenarios. STCT achieves 96.9% label correction and 95.2% classification performance on CIFAR-10 with 80% symmetric noise, significantly surpassing the current state-of-the-art.

cs.LG↗

arXiv2025

Leveraging Labelled Data Knowledge: A Cooperative Rectification Learning Network for Semi-supervised 3D Medical Image Segmentation

Semi-supervised 3D medical image segmentation aims to achieve accurate segmentation using few labelled data and numerous unlabelled data. The main challenge in the design of semi-supervised learning methods consists in the effective use of the unlabelled data for training. A promising solution consists of ensuring consistent predictions across different views of the data, where the efficacy of this strategy depends on the accuracy of the pseudo-labels generated by the model for this consistency learning strategy. In this paper, we introduce a new methodology to produce high-quality pseudo-labels for a consistency learning strategy to address semi-supervised 3D medical image segmentation. The methodology has three important contributions. The first contribution is the Cooperative Rectification Learning Network (CRLN) that learns multiple prototypes per class to be used as external knowledge priors to adaptively rectify pseudo-labels at the voxel level. The second contribution consists of the Dynamic Interaction Module (DIM) to facilitate pairwise and cross-class interactions between prototypes and multi-resolution image features, enabling the production of accurate voxel-level clues for pseudo-label rectification. The third contribution is the Cooperative Positive Supervision (CPS), which optimises uncertain representations to align with unassertive representations of their class distributions, improving the model's accuracy in classifying uncertain regions. Extensive experiments on three public 3D medical segmentation datasets demonstrate the effectiveness and superiority of our semi-supervised learning method.

cs.CV↗

arXiv2025

AEON: Adaptive Estimation of Instance-Dependent In-Distribution and Out-of-Distribution Label Noise for Robust Learning

Robust training with noisy labels is a critical challenge in image classification, offering the potential to reduce reliance on costly clean-label datasets. Real-world datasets often contain a mix of in-distribution (ID) and out-of-distribution (OOD) instance-dependent label noise, a challenge that is rarely addressed simultaneously by existing methods and is further compounded by the lack of comprehensive benchmarking datasets. Furthermore, even though current noisy-label learning approaches attempt to find noisy-label samples during training, these methods do not aim to estimate ID and OOD noise rates to promote their effectiveness in the selection of such noisy-label samples, and they are often represented by inefficient multi-stage learning algorithms. We propose the Adaptive Estimation of Instance-Dependent In-Distribution and Out-of-Distribution Label Noise (AEON) approach to address these research gaps. AEON is an efficient one-stage noisy-label learning methodology that dynamically estimates instance-dependent ID and OOD label noise rates to enhance robustness to complex noise settings. Additionally, we introduce a new benchmark reflecting real-world ID and OOD noise scenarios. Experiments demonstrate that AEON achieves state-of-the-art performance on both synthetic and real-world datasets

cs.CV↗

arXiv2024

Coverage-Constrained Human-AI Cooperation with Multiple Experts

Human-AI cooperative classification (HAI-CC) approaches aim to develop hybrid intelligent systems that enhance decision-making in various high-stakes real-world scenarios by leveraging both human expertise and AI capabilities. Current HAI-CC methods primarily focus on learning-to-defer (L2D), where decisions are deferred to human experts, and learning-to-complement (L2C), where AI and human experts make predictions cooperatively. However, a notable research gap remains in effectively exploring both L2D and L2C under diverse expert knowledge to improve decision-making, particularly when constrained by the cooperation cost required to achieve a target probability for AI-only selection (i.e., coverage). In this paper, we address this research gap by proposing the Coverage-constrained Learning to Defer and Complement with Specific Experts (CL2DC) method. CL2DC makes final decisions through either AI prediction alone or by deferring to or complementing a specific expert, depending on the input data. Furthermore, we propose a coverage-constrained optimisation to control the cooperation cost, ensuring it approximates a target probability for AI-only selection. This approach enables an effective assessment of system performance within a specified budget. Also, CL2DC is designed to address scenarios where training sets contain multiple noisy-label annotations without any clean-label references. Comprehensive evaluations on both synthetic and real-world datasets demonstrate that CL2DC achieves superior performance compared to state-of-the-art HAI-CC methods.

cs.LG↗

arXiv2024

Fair Distillation: Teaching Fairness from Biased Teachers in Medical Imaging

Deep learning has achieved remarkable success in image classification and segmentation tasks. However, fairness concerns persist, as models often exhibit biases that disproportionately affect demographic groups defined by sensitive attributes such as race, gender, or age. Existing bias-mitigation techniques, including Subgroup Re-balancing, Adversarial Training, and Domain Generalization, aim to balance accuracy across demographic groups, but often fail to simultaneously improve overall accuracy, group-specific accuracy, and fairness due to conflicts among these interdependent objectives. We propose the Fair Distillation (FairDi) method, a novel fairness approach that decomposes these objectives by leveraging biased ``teacher'' models, each optimized for a specific demographic group. These teacher models then guide the training of a unified ``student'' model, which distills their knowledge to maximize overall and group-specific accuracies, while minimizing inter-group disparities. Experiments on medical imaging datasets show that FairDi achieves significant gains in both overall and group-specific accuracy, along with improved fairness, compared to existing methods. FairDi is adaptable to various medical tasks, such as classification and segmentation, and provides an effective solution for equitable model performance.

cs.CV↗

arXiv2024

ANNE: Adaptive Nearest Neighbors and Eigenvector-based Sample Selection for Robust Learning with Noisy Labels

An important stage of most state-of-the-art (SOTA) noisy-label learning methods consists of a sample selection procedure that classifies samples from the noisy-label training set into noisy-label or clean-label subsets. The process of sample selection typically consists of one of the two approaches: loss-based sampling, where high-loss samples are considered to have noisy labels, or feature-based sampling, where samples from the same class tend to cluster together in the feature space and noisy-label samples are identified as anomalies within those clusters. Empirically, loss-based sampling is robust to a wide range of noise rates, while feature-based sampling tends to work effectively in particular scenarios, e.g., the filtering of noisy instances via their eigenvectors (FINE) sampling exhibits greater robustness in scenarios with low noise rates, and the K nearest neighbor (KNN) sampling mitigates better high noise-rate problems. This paper introduces the Adaptive Nearest Neighbors and Eigenvector-based (ANNE) sample selection methodology, a novel approach that integrates loss-based sampling with the feature-based sampling methods FINE and Adaptive KNN to optimize performance across a wide range of noise rate scenarios. ANNE achieves this integration by first partitioning the training set into high-loss and low-loss sub-groups using loss-based sampling. Subsequently, within the low-loss subset, sample selection is performed using FINE, while the high-loss subset employs Adaptive KNN for effective sample selection. We integrate ANNE into the noisy-label learning state of the art (SOTA) method SSR+, and test it on CIFAR-10/-100 (with symmetric, asymmetric and instance-dependent noise), Webvision and ANIMAL-10, where our method shows better accuracy than the SOTA in most experiments, with a competitive training time.

cs.CV↗

arXiv2024

Human-AI Collaborative Multi-modal Multi-rater Learning for Endometriosis Diagnosis

Endometriosis, affecting about 10% of individuals assigned female at birth, is challenging to diagnose and manage. Diagnosis typically involves the identification of various signs of the disease using either laparoscopic surgery or the analysis of T1/T2 MRI images, with the latter being quicker and cheaper but less accurate. A key diagnostic sign of endometriosis is the obliteration of the Pouch of Douglas (POD). However, even experienced clinicians struggle with accurately classifying POD obliteration from MRI images, which complicates the training of reliable AI models. In this paper, we introduce the Human-AI Collaborative Multi-modal Multi-rater Learning (HAICOMM) methodology to address the challenge above. HAICOMM is the first method that explores three important aspects of this problem: 1) multi-rater learning to extract a cleaner label from the multiple "noisy" labels available per training sample; 2) multi-modal learning to leverage the presence of T1/T2 MRI images for training and testing; and 3) human-AI collaboration to build a system that leverages the predictions from clinicians and the AI model to provide more accurate classification than standalone clinicians and AI models. Presenting results on the multi-rater T1/T2 MRI endometriosis dataset that we collected to validate our methodology, the proposed HAICOMM model outperforms an ensemble of clinicians, noisy-label learning models, and multi-rater learning methods.

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