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Hao He

Publications and source records attributed to Hao He.

131 records · Page 8Linked to original sources

A Coalitional Game for Distributed Inference in Sensor Networks with Dependent Observations

We consider the problem of collaborative inference in a sensor network with heterogeneous and statistically dependent sensor observations. Each sensor aims to maximize its inference performance by forming a coalition with other sensors and sharing information within the coalition. It is proved that the inference performance is a nondecreasing function of the coalition size. However, in an energy constrained network, the energy consumption of inter-sensor communication also increases with increasing coalition size, which discourages the formation of the grand coalition (the set of all sensors). In this paper, the formation of non-overlapping coalitions with statistically dependent sensors is investigated under a specific communication constraint. We apply a game theoretical approach to fully explore and utilize the information contained in the spatial dependence among sensors to maximize individual sensor performance. Before formulating the distributed inference problem as a coalition formation game, we first quantify the gain and loss in forming a coalition by introducing the concepts of diversity gain and redundancy loss for both estimation and detection problems. These definitions, enabled by the statistical theory of copulas, allow us to characterize the influence of statistical dependence among sensor observations on inference performance. An iterative algorithm based on merge-and-split operations is proposed for the solution and the stability of the proposed algorithm is analyzed. Numerical results are provided to demonstrate the superiority of our proposed game theoretical approach.

cs.IT↗

Fusing Censored Dependent Data for Distributed Detection

In this paper, we consider a distributed detection problem for a censoring sensor network where each sensor's communication rate is significantly reduced by transmitting only "informative" observations to the Fusion Center (FC), and censoring those deemed "uninformative". While the independence of data from censoring sensors is often assumed in previous research, we explore spatial dependence among observations. Our focus is on designing the fusion rule under the Neyman-Pearson (NP) framework that takes into account the spatial dependence among observations. Two transmission scenarios are considered, one where uncensored observations are transmitted directly to the FC and second where they are first quantized and then transmitted to further improve transmission efficiency. Copula-based Generalized Likelihood Ratio Test (GLRT) for censored data is proposed with both continuous and discrete messages received at the FC corresponding to different transmission strategies. We address the computational issues of the copula-based GLRTs involving multidimensional integrals by presenting more efficient fusion rules, based on the key idea of injecting controlled noise at the FC before fusion. Although, the signal-to-noise ratio (SNR) is reduced by introducing controlled noise at the receiver, simulation results demonstrate that the resulting noise-aided fusion approach based on adding artificial noise performs very closely to the exact copula-based GLRTs. Copula-based GLRTs and their noise-aided counterparts by exploiting the spatial dependence greatly improve detection performance compared with the fusion rule under independence assumption.

stat.AP↗

Photostimulation activates restorable fragmentation of single mitochondrion by initiating oxide flashes

Mitochondrial research is important to ageing, apoptosis, and mitochondrial diseases. In previous works, mitochondria are usually stimulated indirectly by proapoptotic drugs to study mitochondrial development, which is in lack of controllability, or spatial and temporal resolution. These chemicals or even gene techniques regulating mitochondrial dynamics may also activate other inter- or intra-cellular processes simultaneously. Here we demonstrate a photostimulation method on single-mitochondrion level by tightly-focused femtosecond laser that can precisely activate restorable fragmentation of mitochondria which soon recover their original tubular structure after tens of seconds. In this process, series of mitochondrial reactive oxygen species (mROS) flashes are observed and found very critical to mitochondrial fragmentation. Meanwhile, transient openings of mitochondrial permeability transition pores (mPTP), suggested by oscillations of mitochondrial membrane potential, contribute to the scavenging of redundant mROS and recovery of fragmented mitochondria. Those results demonstrate photostimulation as an active, precise and controllable method for the study of mitochondrial oxidative and morphological dynamics or related fields.

q-bio.SC↗

On Quantizer Design for Distributed Bayesian Estimation in Sensor Networks

We consider the problem of distributed estimation under the Bayesian criterion and explore the design of optimal quantizers in such a system. We show that, for a conditionally unbiased and efficient estimator at the fusion center and when local observations have identical distributions, it is optimal to partition the local sensors into groups, with all sensors within a group using the same quantization rule. When all the sensors use identical number of decision regions, use of identical quantizers at the sensors is optimal. When the network is constrained by the capacity of the wireless multiple access channel over which the sensors transmit their quantized observations, we show that binary quantizers at the local sensors are optimal under certain conditions. Based on these observations, we address the location parameter estimation problem and present our optimal quantizer design approach. We also derive the performance limit for distributed location parameter estimation under the Bayesian criterion and find the conditions when the widely used threshold quantizer achieves this limit. We corroborate this result using simulations. We then relax the assumption of conditionally independent observations and derive the optimality conditions of quantizers for conditionally dependent observations. Using counter-examples, we also show that the previous results do not hold in this setting of dependent observations and, therefore, identical quantizers are not optimal.

cs.IT↗

Observation of Multiphoton-induced Fluorescence from Nano Graphene Oxide and Its Applications in In vitro and In vivo Bioimaging

In the present paper, we observed both two-photon and three-photon induced distinct photoluminescence from GO nanoparticles under fs laser excitation. Conjugated with PEG molecules, GO nanoparticles exhibited high chemical stability, and could effectively label HeLa cells. Imaged with a two-photon scanning microscope, GO nanoparticles were observed to localize in the mitochondria, endoplasmic reticulum, Golgi and lysosome of HeLa cells. Furthermore, GO nanoparticles were micro-injected into the brain of a black mouse, and in vivo two-photon luminescence imaging illustrated that GO nanoparticles located at 300 μm depth in the brain could be clearly distinguished.

physics.optics↗