Ian Newsome | Searcharxiv

arXiv2026

Tools to help patients and other stakeholders' input into choice of estimand and intercurrent event strategy in randomised trials

Estimands can help to clarify the research questions being addressed in randomised trials. Because the choice of estimand can affect how relevant trial results are to patients and other stakeholders, such as clinicians or policymakers, it is important for them to be involved in these decisions. However, there are barriers to having these conversations. For instance, discussions around how intercurrent events should be addressed in the estimand definition typically involve complex concepts as well as technical language. We three tools to facilitate conversations between researchers and patients and other stakeholders about the choice of estimand and intercurrent event strategy: (i) a video explaining the concept of an estimand and the five different ways that intercurrent events can be incorporated into the estimand definition; (ii) an infographic outlining these five strategies; and (iii) an editable PowerPoint slide which can be completed with trial-specific details to facilitate conversations around choice of estimand for a particular trial. These resources can help to start conversations between the trial team and patients and other stakeholders about the best choice of estimand and intercurrent event strategies for a randomised trial.

stat.ME↗

arXiv2015

An evaluation of the membership probability of 212 $λ$ Boo stars: I. A Catalogue

The literature on the $λ$ Boo stars has grown to become somewhat heterogenous, as different authors have applied different criteria across the UV, optical and infrared regions to determine the membership status of $λ$ Boo candidates. We aim to clear up the confusion by consulting the literature on 212 objects that have been considered as $λ$ Boo candidates, and subsequently evaluating the evidence in favour of their admission to the $λ$ Boo class. We obtained new spectra of $\sim$90 of these candidates and classified them on the MK system to aid in the membership evaluations. The re-evaluation of the 212 objects resulted in 64 members and 103 non-members of the $λ$ Boo class, with a further 45 stars for which membership status is unclear. We suggest observations for each of the stars in the latter category that will allow them to be confidently included or rejected from the class. Our reclassification facilitates homogenous analysis on group members, and represents the largest collection of confirmed $λ$ Boo stars known.

astro-ph.SR↗