arXiv subjects

Jian-Ping Wang

Publications and source records attributed to Jian-Ping Wang.

At least 55 records · Page 3Linked to original sources

arXiv2021

Magnetic Particle Spectroscopy (MPS) with One-stage Lock-in Implementation for Magnetic Bioassays with Improved Sensitivities

In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection of target analytes in liquid phase. There are many research studies reporting the application of MPS for detecting a variety of analytes including viruses, toxins, and nucleic acids, etc. Herein, we report a modified version of MPS platform with the addition of a one-stage lock-in design to remove the feedthrough signals induced by external driving magnetic fields, thus capturing only MNP responses for improved system sensitivity. This one-stage lock-in MPS system is able to detect as low as 781 ng multi-core Nanomag50 iron oxide MNPs (micromod Partikeltechnologie GmbH) and 78 ng single-core SHB30 iron oxide MNPs (Ocean NanoTech). In addition, using a streptavidin-biotin binding system as a proof-of-concept, we show that these single-core SHB30 MNPs can be used for Brownian relaxation-based bioassays while the multi-core Nanomag50 cannot be used. The effects of MNP amount on the concentration dependent response profiles for detecting streptavidin was also investigated. Results show that by using lower concentration/amount of MNPs, concentration-response curves shift to lower concentration/amount of target analytes. This lower concentrationresponse indicates the possibility of improved bioassay sensitivities by using lower amounts of MNPs.

physics.app-ph↗

arXiv2021

Roadmap of spin-orbit torques

Spin-orbit torque (SOT) is an emerging technology that enables the efficient manipulation of spintronic devices. The initial processes of interest in SOTs involved electric fields, spin-orbit coupling, conduction electron spins and magnetization. More recently interest has grown to include a variety of other processes that include phonons, magnons, or heat. Over the past decade, many materials have been explored to achieve a larger SOT efficiency. Recently, holistic design to maximize the performance of SOT devices has extended material research from a nonmagnetic layer to a magnetic layer. The rapid development of SOT has spurred a variety of SOT-based applications. In this Roadmap paper, we first review the theories of SOTs by introducing the various mechanisms thought to generate or control SOTs, such as the spin Hall effect, the Rashba-Edelstein effect, the orbital Hall effect, thermal gradients, magnons, and strain effects. Then, we discuss the materials that enable these effects, including metals, metallic alloys, topological insulators, two-dimensional materials, and complex oxides. We also discuss the important roles in SOT devices of different types of magnetic layers. Afterward, we discuss device applications utilizing SOTs. We discuss and compare three-terminal and two-terminal SOT-magnetoresistive random-access memories (MRAMs); we mention various schemes to eliminate the need for an external field. We provide technological application considerations for SOT-MRAM and give perspectives on SOT-based neuromorphic devices and circuits. In addition to SOT-MRAM, we present SOT-based spintronic terahertz generators, nano-oscillators, and domain wall and skyrmion racetrack memories. This paper aims to achieve a comprehensive review of SOT theory, materials, and applications, guiding future SOT development in both the academic and industrial sectors.

cond-mat.mes-hall↗

arXiv2021

Surface Acoustic Wave induced modulation of tunneling magnetoresistance in magnetic tunnel junctions

We show that a surface acoustic wave (SAW) applied across the terminals of a magnetic tunnel junction (MTJ) decreases both the (time-averaged) parallel and antiparallel resistances of the MTJ, with the latter decreasing much more than the former. This results in a decrease of the tunneling magnetoresistance (TMR) ratio. The coercivities of the free and fixed layer of the MTJ, however, are not affected significantly, suggesting that the SAW does not cause large-angle magnetization rotation in the magnetic layers through the inverse magnetostriction (Villari) effect at the power levels used. This study sheds light on the dynamical behavior of an MTJ under periodic compressive and tensile strain.

cond-mat.mes-hall↗

arXiv2021

Large field-like torque in amorphous Ru2Sn3 originated from the intrinsic spin Hall effect

We investigated temperature dependent current driven spin-orbit torques in magnetron sputtered Ru2Sn3 (4 and 10 nm) /Co20Fe60B20 (5 nm) layered structures with in-plane magnetic anisotropy. The room temperature damping-like and field-like spin torque efficiencies of the amorphous Ru2Sn3 films were measured to be 0.14 +- 0.008 (0.07 +- 0.012) and -0.03 +- 0.006 (-0.20 +- 0.009), for the 4 (10 nm) films respectively, by utilizing the second harmonic Hall technique. The large field-like torque in the relatively thicker Ru2Sn3 (10 nm) thin film is unique compared to the traditional spin Hall materials interfaced with thick magnetic layers with in-plane magnetic anisotropy which typically have dominant damping-like and negligible field-like torques. Additionally, the observed room temperature field-like torque efficiency in Ru2Sn3 (10 nm)/CoFeB (5 nm) is up to three times larger than the damping-like torque (-0.20 +- 0.009 and 0.07 +- 0.012, respectively) and thirty times larger at 50 K (-0.29 +- 0.014 and 0.009 +- 0.017, respectively). The temperature dependence of the field-like torques show dominant contributions from the intrinsic spin Hall effect while the damping-like torques show dominate contributions from the extrinsic spin Hall effects, skew scattering and side jump. Through macro-spin calculations, we found that including field-like torques on the order or larger than the damping-like torque can reduce the switching critical current and decrease magnetization procession for a perpendicular ferromagnetic layer.

cond-mat.mes-hall↗

arXiv2021

Voltage-controlled antiferromagnetism in magnetic tunnel junctions

We demonstrate a voltage-controlled exchange bias effect in CoFeB/MgO/CoFeB magnetic tunnel junctions that is related to the interfacial Fe(Co)Ox formed between the CoFeB electrodes and the MgO barrier. The unique combination of interfacial antiferromagnetism, giant tunneling magnetoresistance, and sharp switching of the perpendicularly-magnetized CoFeB allows sensitive detection of the exchange bias. It is found that the exchange bias field can be isothermally controlled by magnetic fields at low temperatures. More importantly, the exchange bias can also be effectively manipulated by the electric field applied to the MgO barrier due to the voltage-controlled antiferromagnetic anisotropy in this system.

cond-mat.mes-hall↗

arXiv2020

An Investigation of Commercial Iron Oxide Nanoparticles: Advanced Structural and Magnetic Properties Characterization

Magnetic nanoparticles (MNPs) have been extensively used as tiny heating sources in magnetic hyperthermia therapy, contrast agents in magnetic resonance imaging (MRI), tracers in magnetic particle imaging (MPI), carriers for drug/gene delivery, etc. There have emerged many magnetic nanoparticle/microbeads suppliers since the last decade, such as Ocean NanoTech, Nanoprobes, US Research Nanomaterials, Miltenyi Biotec, micromod Partikeltechnologie GmbH, and nanoComposix, etc. In this paper, we report the physical and magnetic characterizations on iron oxide nanoparticle products from Ocean NanoTech. Standard characterization tools such as Vibrating-Sample Magnetometer (VSM), X-Ray Diffraction (XRD), Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM), and Zeta Potential Analyzer are used to provide magnetic nanoparticle customers and researchers with an overview of these iron oxide nanoparticle products. In addition, the dynamic magnetic responses of these iron oxide nanoparticles in aqueous solutions are investigated under low and high frequency alternating magnetic fields, giving a standardized operating procedure for characterizing the MNPs from Ocean NanoTech, thereby yielding the best of magnetic nanoparticles for different applications.

physics.app-ph↗

arXiv2020

Portable Magnetic Particle Spectrometer (MPS) for Future Rapid and Wash-free Bioassays

Nowadays, there is an increasing demand for more accessible routine diagnostics for patients with respect to high accuracy, ease of use, and low cost. However, the quantitative and high accuracy bioassays in large hospitals and laboratories usually require trained technicians and equipment that is both bulky and expensive. In addition, the multi-step bioassays and long turnaround time could severely affect the disease surveillance and control especially in pandemics such as influenza and COVID-19. In view of this, a portable, quantitative bioassay device will be valuable in regions with scarce medical resources and help relieve burden on local healthcare systems. Herein, we introduce the MagiCoil diagnostic device, an inexpensive, portable, quantitative and rapid bioassay platform based on magnetic particle spectrometer (MPS) technique. MPS detects the dynamic magnetic responses of magnetic nanoparticles (MNPs) and uses the harmonics from oscillating MNPs as metrics for sensitive and quantitative bioassays. This device does not require trained technicians to operate and employs a fully automatic, one-step, wash-free assay with user friendly smartphone interface. Using a streptavidin-biotin binding system as a model, we show that the detection limit of the current portable device for streptavidin is 64 nM (equal to 5.12 pmole). In addition, this MPS technique is very versatile and allows for the detection of different diseases just by changing the surface modifications on MNPs.

physics.med-ph↗

arXiv2020

Giant Anomalous Hall Effect due to Double-Degenerate Quasi Flat Bands

We propose a novel approach to achieve giant AHE in materials with flat bands (FBs). FBs are accompanied by small electronic bandwidths, which consequently increases the momentum separation ($K$) within pair of Weyl points and thus the integrated Berry curvature. Starting from a simple model with a single pair of Weyl nodes, we demonstrated the increase of $K$ and AHE by decreasing bandwidth. It is further expanded to a realistic pyrochlore lattice model with characteristic double degenerated FBs, where we discovered a giant AHE while maximizing the $K$ with nearly vanishing band dispersion of FBs. We identify that such model system can be realized in both pyrochlore and spinel compounds based on first-principles calculations, validating our theoretical model and providing a feasible platform for experimental exploration.

cond-mat.mtrl-sci↗

arXiv2020

Ferromagnetic phase of spinel compound MgV$_2$O$_4$ and its spintronics properties

Spinel compound, MgV$_2$O$_4$, known as a highly frustrated magnet has been extensively studied both experimentally and theoretically for its exotic quantum magnetic states. However, due to its intrinsic insulating nature in its antiferromagnetic (AFM) ground state, its realistic applications in spintronics are quite limited. Here, based on first-principles calculations, we examine the ferromagnetic (FM) phase of MgV$_2$O$_4$, which was found to host three-dimensional flat band (FB) right near the Fermi level, consequently yielding a large anomalous Hall effect (AHE, $σ\approx 670\,Ω^{-1}\cdot cm^{-1}$). Our calculations suggest that the half-metallicity feature of MgV$_2$O$_4$ is preserved even after interfacing with MgO due to the excellent lattice matching, which could be a promising spin filtering material for spintronics applications. Lastly, we explore experimental feasibility of stabilizing this FM phase through strain and doping engineering. Our study suggests that experimentally accessible amount of hole doping might induce a AFM-FM phase transition.

cond-mat.mtrl-sci↗

arXiv2020

Ultra-high frequency magnetic resonance through strain-spin coupling in perpendicular magnetic multi-layers

The interaction between strain and spin has received intensive attention in the scientific community due to its abundant physical phenomena and huge technological impact. Until now, there is no experimental report on ultra-high frequency magnetic resonance through the strain-spin coupling for any technologically relevant perpendicular magnetic material. Here we report the experimental detection of the acoustic strain waves that have a response time on the order of 10 picoseconds in perpendicular magnetic [Co/Pd]n multilayers via a femtosecond laser pulse excitation. Through direct measurements of acoustic strain waves, we observe an ultra-high frequency magnetic resonance up to 60 GHz in [Co/Pd]n multilayers. We further report a theoretical model of the strain-spin interaction. Our model reveals that the energy could be transferred efficiently from the strain to the spins and well explains the existence of a steady resonance state through exciting the spin system. The physical origins of the resonance between strain waves and magnetic precession and the requested conditions for obtaining magnetic resonance within thin magnetic films have also been discussed after thorough analysis. These combined results point out a potential pathway to enable an extremely high frequency (EHF) magnetic resonance through the strain-spin coupling.

cond-mat.mtrl-sci↗

arXiv2020

Magnetic Immunoassays: A Review of Virus and Pathogen Detection Before and Amidst the Coronavirus Disease-19 (COVID-19)

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a threat to the global healthcare system and economic security. As of July 2020, no specific drugs or vaccines are yet available for COVID-19, fast and accurate diagnosis for SARS-CoV-2 is essential in slowing down the spread of COVID-19 and for efficient implementation of control and containment strategies. Magnetic immunoassay is a novel and emerging topic representing the frontiers of current biosensing and magnetics areas. The past decade has seen rapid growth in applying magnetic tools for biological and biomedical applications. Recent advances in magnetic materials and nanotechnologies have transformed current diagnostic methods to nanoscale and pushed the detection limit to early stage disease diagnosis. Herein, this review covers the literatures of magnetic immunoassay platforms for virus and pathogen detections, before COVID-19. We reviewed the popular magnetic immunoassay platforms including magnetoresistance (MR) sensors, magnetic particle spectroscopy (MPS), and nuclear magnetic resonance (NMR). Magnetic Point-of-Care (POC) diagnostic kits are also reviewed aiming at developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak as well as preventing future epidemics. In addition, other platforms that use magnetic materials as auxiliary tools for enhanced pathogen and virus detections are also covered. The goal of this review is to inform the researchers of diagnostic and surveillance platforms for SARS-CoV-2 and their performances.

physics.med-ph↗

arXiv2020

An Inference and Learning Engine for Spiking Neural Networks in Computational RAM (CRAM)

Spiking Neural Networks (SNN) represent a biologically inspired computation model capable of emulating neural computation in human brain and brain-like structures. The main promise is very low energy consumption. Unfortunately, classic Von Neumann architecture based SNN accelerators often fail to address demanding computation and data transfer requirements efficiently at scale. In this work, we propose a promising alternative, an in-memory SNN accelerator based on Spintronic Computational RAM (CRAM) to overcome scalability limitations, which can reduce the energy consumption by up to 164.1$\times$ when compared to a representative ASIC solution.

cs.ET↗

arXiv2020

Magnetic Particle Spectroscopy: A Short Review of Applications

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was primarily designed for characterizing superparamagnetic iron oxide nanoparticles (SPIONs) regarding their applicability for MPI. In recent years, it has evolved into an independent, versatile, highly sensitive, inexpensive platform for biological and biomedical assays, cell labeling and tracking, and blood analysis. MPS has also developed into an auxiliary tool for magnetic imaging and hyperthermia by providing high spatial and temporal mappings of temperature and viscosity. Furthermore, other MPS-based applications are being explored such as magnetic fingerprints for product tracking and identification in supply chains. There are a variety of novel MPS-based applications being reported and demonstrated by many groups. In this short review, we highlighted some of the representative applications based on MPS platform, thereby providing a roadmap of this technology and our insights for researchers in this area.

physics.app-ph↗

arXiv2020

Single-core Or Multi-core? A Mini Review on Magnetic Nanoparticles for Magnetic Particle Spectroscopy-based Bioassays

Magnetic particle spectroscopy (MPS) is a technology that derives from magnetic particle imaging (MPI) and thrives as a standalone platform for many biological and biomedical applications, benefiting from the facile preparation and chemical modification of magnetic nanoparticles (MNPs). In recent years, MPS has been reported in extensive literatures as a versatile platform for different bioassay purposes using artificially designed MNPs, where the MNPs serve as magnetic tracers, the surface functionalized reagents (e.g., antibodies, aptamers, peptides, etc.) and tiny probes capturing target analytes from biofluid samples. The biochemical complexes on MNP surfaces can be tailored for different bioassay requirements, while the design of MNPs are of less attention for MPS-based bioassays. For MNPs in most bioassay applications, superparamagnetism is prerequisite to avoid agglomerates and false magnetic signals. Single- and multi-core superparamagnetic nanoparticles (SPMNPs) are prevalently used in MPS-based bioassays. In this mini review, we compared the pros & cons of different MPS platforms realizing volumetric- and surface-based bioassays with single- and multi-core nanoparticles, respectively.

physics.app-ph↗

arXiv2019

Irregularly Shaped γ'-Fe4N Nanoparticles for Hyperthermia Treatment and T2 Contrast-Enhanced Magnetic Resonance Imaging with Minimum Dose

Magnetic nanoparticles (MNPs) have been extensively used in drug/gene delivery, hyperthermia therapy, magnetic particle imaging (MPI), magnetic resonance imaging (MRI), magnetic bioassays, etc. With proper surface chemical modifications, physicochemically stable and non-toxic MNPs are emerging contrast agents and tracers for in vivo MRI and MPI applications. Herein, we report the high magnetic moment, irregularly shaped γ'-Fe4N nanoparticles for enhanced hyperthermia therapy and T2 contrast agent for MRI application. The static and dynamic magnetic properties of γ'-Fe4N nanoparticles are characterized by vibrating sample magnetometer (VSM) and magnetic particle spectroscopy (MPS) systems, respectively. Compared to the γ-Fe2O3 nanoparticles, γ'-Fe4N show at least 3 times higher saturation magnetization (in emu/g), which, as a result, gives rise to the stronger dynamic magnetic responses as proved in the MPS measurement results. In addition, γ'-Fe4N nanoparticles are functionalized with oleic acid layer by a wet mechanical milling process, the morphologies of as-milled nanoparticles are characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS) and nanoparticle tracking analyzer (NTA). We report that with proper surface chemical modification and tuning on morphologies, γ'-Fe4N nanoparticles could be used as tiny heating sources for hyperthermia and contrast agents for MRI applications with minimum dose.

physics.app-ph↗

arXiv2019

Magnetic Weyl semimetals with diamond structure realized in spinel compounds

Diamond-structure materials have been extensively studied for decades, which form the foundation for most semiconductors and their modern day electronic devices. Here, we discover a e$_g$-orbital ($d_{z^2}$,$d_{x^2-y^2}$ ) model within the diamond lattice (e$_g$-diamond model) that hosts novel topological states. Specifically, the e$_g$-diamond model yields a 3D nodal cage (3D-NC), which is characterized by a $d$-$d$ band inversion protected by two types of degenerate states (i.e., e$_g$-orbital and diamond-sublattice degeneracies). We demonstrate materials realization of this model in the well-known spinel compounds (AB$_2$X$_4$), where the tetrahedron-site cations (A) form the diamond sub-lattice. An ideal half metal with one metallic spin channel formed by well-isolated and half-filled e$_g$-diamond bands, accompanied by a large spin gap (4.36 eV) is discovered in one 4-2 spinel compound (VMg$_2$O$_4$), which becomes a magnetic Weyl semimetal when spin-orbit coupling effect is further considered. Our discovery greatly enriches the physics of diamond structure and spinel compounds, opening a door to their application in spintronics.

cond-mat.mtrl-sci↗

arXiv2019

Detection of magnetic nanoparticles (MNPs) using spin current nano-oscillator (SCNO) biosensor: A frequency-based rapid, ultra-sensitive, magnetic bioassay

This Letter is a micromagnetic simulation-based study on the GHz-frequency ferromagnetic resonances for the detection of magnetic nanoparticles (MNPs) using spin current nano-oscillator (SCNO) operating in precession mode as a spintronic biosensor. The magnetic stray fields from the MNPs in an antibody-antigen-MNP complex on the SCNO surface modify the ferromagnetic resonance peaks and generate measurable resonance peak shifts. Moreover, our results strongly indicate the position-sensitive behavior of the SCNO biosensor and ways to eradicate this effect to facilitate better bio-sensing performance. Additionally, a study has been made on how nanoparticles with different sizes can alter the SCNO device performance. This simulation-based study on the SCNO device shows a promise of frequency-based nano-biosensor with a sensitivity of detecting even a single MNP, even in presence of thermal noise.

physics.app-ph↗

arXiv2019

Experimental Demonstration of Probabilistic Spin Logic by Magnetic Tunnel Junctions

The recently proposed probabilistic spin logic presents promising solutions to novel computing applications. Multiple cases of implementations, including invertible logic gate, have been studied numerically by simulations. Here we report an experimental demonstration of a magnetic tunnel junction-based hardware implementation of probabilistic spin logic.

cs.ET↗