SearcharxivSearch

arXiv subjects

Jing Yan

Publications and source records attributed to Jing Yan.

At least 19 recordsLinked to original sources

How Much MRI Preprocessing Is Enough? A Cost-Utility Study for Brain MRI Foundation Models

MRI preprocessing defines the input distribution seen by brain MRI foundation models, yet it is usually treated as routine data cleaning rather than a modeling choice. We ask how much preprocessing is worth its computational cost for self-supervised 3D MRI pretraining. Keeping the corpus, 3D ViT backbone, masking protocol, and downstream evaluations fixed, we compare a graded P0-P7 preprocessing spectrum for masked autoencoding (MAE) and joint-embedding predictive learning (JEPA) on 20,000 heterogeneous brain MRI volumes, then transfer the encoders to IDH prediction, MCI classification, brain age regression, and GLI/PED tumor segmentation. The results do not support a simple "more is better" rule. P0/P1 are numerically unstable, making P2 the lowest-cost feasible level; beyond P2, choosing the best feasible preprocessing level improves aggregate utility by only 3.4 percentage points for MAE and 1.8 percentage points for JEPA, with most paired gains statistically unresolved. Stronger preprocessing is beneficial only in selected regimes: IDH improves modestly, AGE and GLI/PED are often near or best at P2, and MCI shows the clearest empirical P7 gain. Cross-level MCI transfer further shows that much of the P7 advantage can be recovered by applying stronger preprocessing downstream, without requiring P7 throughout pretraining. These findings recast MRI preprocessing as a downstream-aware cost-utility decision rather than a default escalation pipeline. Code is available at https://github.com/PangJiangShuan/PreBrain.

cs.CV

Determinism in the Undetermined: Deterministic Output in Charge-Conserving Continuous-Time Neuromorphic Systems with Temporal Stochasticity

Achieving deterministic computation results in asynchronous neuromorphic systems remains a fundamental challenge due to the inherent temporal stochasticity of continuous-time hardware. To address this, we develop a unified continuous-time framework for spiking neural networks (SNNs) that couples the Law of Charge Conservation with minimal neuron-level constraints. This integration ensures that the terminal state depends solely on the aggregate input charge, providing a unique cumulated output invariant to temporal stochasticity. We prove that this mapping is strictly invariant to spike timing in acyclic networks, whereas recurrent connectivity can introduce temporal sensitivity. Furthermore, we establish an exact representational correspondence between these charge-conserving SNNs and quantized artificial neural networks, bridging the gap between static deep learning and event-driven dynamics without approximation errors. These results establish a rigorous theoretical basis for designing continuous-time neuromorphic systems that harness the efficiency of asynchronous processing while maintaining algorithmic determinism.

cs.LG

MERGE: Next-Generation Item Indexing Paradigm for Large-Scale Streaming Recommendation

Item indexing, which maps a large corpus of items into compact discrete representations, is critical for both discriminative and generative recommender systems, yet existing Vector Quantization (VQ)-based approaches struggle with the highly skewed and non-stationary item distributions common in industrial streaming recommenders, leading to poor assignment accuracy, imbalanced cluster occupancy, and insufficient cluster separation. To address these challenges, we propose MERGE, a next-generation item indexing paradigm that adaptively constructs clusters from scratch, dynamically monitors cluster occupancy, and forms hierarchical index structures via fine-to-coarse merging. Extensive experiments demonstrate that MERGE significantly improves assignment accuracy, cluster uniformity, and cluster separation compared with existing indexing methods, while online A/B tests show substantial gains in key business metrics, highlighting its potential as a foundational indexing approach for large-scale recommendation. Codes are available at https://github.com/baiyimeng/MERGE.

cs.IR

EIRES:Training-free AI-Generated Image Detection via Edit-Induced Reconstruction Error Shift

Diffusion models have recently achieved remarkable photorealism, making it increasingly difficult to distinguish real images from generated ones, raising significant privacy and security concerns. In response, we present a key finding: structural edits enhance the reconstruction of real images while degrading that of generated images, creating a distinctive edit-induced reconstruction error shift. This asymmetric shift enhances the separability between real and generated images. Building on this insight, we propose EIRES, a training-free method that leverages structural edits to reveal inherent differences between real and generated images. To explain the discriminative power of this shift, we derive the reconstruction error lower bound under edit perturbations. Since EIRES requires no training, thresholding depends solely on the natural separability of the signal, where a larger margin yields more reliable detection. Extensive experiments show that EIRES is effective across diverse generative models and remains robust on the unbiased subset, even under post-processing operations.

cs.CV

PoEmotion: Can AI Utilize Chinese Calligraphy to Express Emotion from Poems?

This paper presents PoEmotion, an approach to visualizing emotions in poetry with Chinese calligraphy strokes. Traditional textual emotion analysis often lacks emotional resonance due to its mechanical nature. PoEmotion combines natural language processing with deep learning generative algorithms to create Chinese calligraphy that effectively conveys the emotions in poetry. The created calligraphy represents four fundamental emotions: excitement, anger, sadness, and relaxation, making the visual representation of emotions intuitive and concise. Furthermore, the approach delves into the relationship be-tween time, emotion, and cultural communication. Its goal is to provide a more natural means of communicating emotions through non-verbal mediums to enhance human emotional expression.

cs.HC

Reconstructing Quantitative Cerebral Perfusion Images Directly From Measured Sinogram Data Acquired Using C-arm Cone-Beam CT

To shorten the door-to-puncture time for better treating patients with acute ischemic stroke, it is highly desired to obtain quantitative cerebral perfusion images using C-arm cone-beam computed tomography (CBCT) equipped in the interventional suite. However, limited by the slow gantry rotation speed, the temporal resolution and temporal sampling density of typical C-arm CBCT are much poorer than those of multi-detector-row CT in the diagnostic imaging suite. The current quantitative perfusion imaging includes two cascaded steps: time-resolved image reconstruction and perfusion parametric estimation. For time-resolved image reconstruction, the technical challenge imposed by poor temporal resolution and poor sampling density causes inaccurate quantification of the temporal variation of cerebral artery and tissue attenuation values. For perfusion parametric estimation, it remains a technical challenge to appropriately design the handcrafted regularization for better solving the associated deconvolution problem. These two challenges together prevent obtaining quantitatively accurate perfusion images using C-arm CBCT. The purpose of this work is to simultaneously address these two challenges by combining the two cascaded steps into a single joint optimization problem and reconstructing quantitative perfusion images directly from the measured sinogram data. In the developed direct cerebral perfusion parametric image reconstruction technique, TRAINER in short, the quantitative perfusion images have been represented as a subject-specific conditional generative model trained under the constraint of the time-resolved CT forward model, perfusion convolutional model, and the subject's own measured sinogram data. Results shown in this paper demonstrated that using TRAINER, quantitative cerebral perfusion images can be accurately obtained using C-arm CBCT in the interventional suite.

eess.IV

RLCP: A Reinforcement Learning-based Copyright Protection Method for Text-to-Image Diffusion Model

The increasing sophistication of text-to-image generative models has led to complex challenges in defining and enforcing copyright infringement criteria and protection. Existing methods, such as watermarking and dataset deduplication, fail to provide comprehensive solutions due to the lack of standardized metrics and the inherent complexity of addressing copyright infringement in diffusion models. To deal with these challenges, we propose a Reinforcement Learning-based Copyright Protection(RLCP) method for Text-to-Image Diffusion Model, which minimizes the generation of copyright-infringing content while maintaining the quality of the model-generated dataset. Our approach begins with the introduction of a novel copyright metric grounded in copyright law and court precedents on infringement. We then utilize the Denoising Diffusion Policy Optimization (DDPO) framework to guide the model through a multi-step decision-making process, optimizing it using a reward function that incorporates our proposed copyright metric. Additionally, we employ KL divergence as a regularization term to mitigate some failure modes and stabilize RL fine-tuning. Experiments conducted on 3 mixed datasets of copyright and non-copyright images demonstrate that our approach significantly reduces copyright infringement risk while maintaining image quality.

cs.CY

State-dependent Filtering of the Ring Model

Robustness is a measure of functional reliability of a system against perturbations. To achieve a good and robust performance, a system must filter out external perturbations by its internal priors. These priors are usually distilled in the structure and the states of the system. Biophysical neural network are known to be robust but the exact mechanisms are still elusive. In this paper, we probe how orientation-selective neurons organized on a 1-D ring network respond to perturbations in the hope of gaining some insights on the robustness of visual system in brain. We analyze the steady-state of the rate-based network and prove that the activation state of neurons, rather than their firing rates, determines how the model respond to perturbations. We then identify specific perturbation patterns that induce the largest responses for different configurations of activation states, and find them to be sinusoidal or sinusoidal-like while other patterns are largely attenuated. Similar results are observed in a spiking ring model. Finally, we remap the perturbations in orientation back into the 2-D image space using Gabor functions. The resulted optimal perturbation patterns mirror adversarial attacks in deep learning that exploit the priors of the system. Our results suggest that based on different state configurations, these priors could underlie some of the illusionary experiences as the cost of visual robustness.

q-bio.NC

Trinity: Syncretizing Multi-/Long-tail/Long-term Interests All in One

Interest modeling in recommender system has been a constant topic for improving user experience, and typical interest modeling tasks (e.g. multi-interest, long-tail interest and long-term interest) have been investigated in many existing works. However, most of them only consider one interest in isolation, while neglecting their interrelationships. In this paper, we argue that these tasks suffer from a common "interest amnesia" problem, and a solution exists to mitigate it simultaneously. We figure that long-term cues can be the cornerstone since they reveal multi-interest and clarify long-tail interest. Inspired by the observation, we propose a novel and unified framework in the retrieval stage, "Trinity", to solve interest amnesia problem and improve multiple interest modeling tasks. We construct a real-time clustering system that enables us to project items into enumerable clusters, and calculate statistical interest histograms over these clusters. Based on these histograms, Trinity recognizes underdelivered themes and remains stable when facing emerging hot topics. Trinity is more appropriate for large-scale industry scenarios because of its modest computational overheads. Its derived retrievers have been deployed on the recommender system of Douyin, significantly improving user experience and retention. We believe that such practical experience can be well generalized to other scenarios.

cs.IR

Flocking by Turning Away

Flocking, as paradigmatically exemplified by birds, is the coherent collective motion of active agents. As originally conceived, flocking emerges through alignment interactions between the agents. Here, we report that flocking can also emerge through interactions that turn agents away from each other. Combining simulations, kinetic theory, and experiments, we demonstrate this mechanism of flocking in self-propelled Janus colloids with stronger repulsion on the front than on the rear. The polar state is stable because particles achieve a compromise between turning away from left and right neighbors. Unlike for alignment interactions, the emergence of polar order from turn-away interactions requires particle repulsion. At high concentration, repulsion produces flocking Wigner crystals. Whereas repulsion often leads to motility-induced phase separation of active particles, here it combines with turn-away torques to produce flocking. Therefore, our findings bridge the classes of aligning and non-aligning active matter. Our results could help to reconcile the observations that cells can flock despite turning away from each other via contact inhibition of locomotion. Overall, our work shows that flocking is a very robust phenomenon that arises even when the orientational interactions would seem to prevent it.

cond-mat.soft

The Blessings of Multiple Treatments and Outcomes in Treatment Effect Estimation

Assessing causal effects in the presence of unobserved confounding is a challenging problem. Existing studies leveraged proxy variables or multiple treatments to adjust for the confounding bias. In particular, the latter approach attributes the impact on a single outcome to multiple treatments, allowing estimating latent variables for confounding control. Nevertheless, these methods primarily focus on a single outcome, whereas in many real-world scenarios, there is greater interest in studying the effects on multiple outcomes. Besides, these outcomes are often coupled with multiple treatments. Examples include the intensive care unit (ICU), where health providers evaluate the effectiveness of therapies on multiple health indicators. To accommodate these scenarios, we consider a new setting dubbed as multiple treatments and multiple outcomes. We then show that parallel studies of multiple outcomes involved in this setting can assist each other in causal identification, in the sense that we can exploit other treatments and outcomes as proxies for each treatment effect under study. We proceed with a causal discovery method that can effectively identify such proxies for causal estimation. The utility of our method is demonstrated in synthetic data and sepsis disease.

stat.ME

Using a virtual reality interview simulator to explore factors influencing people's behavior

Virtual reality interview simulator (VRIS) provides an effective and manageable approach for candidates prone to being very nervous during interviews, yet, the major anxiety-inducing elements remain unknown. During an interview, the anxiety levels, overall experience, and performance of interviewees might be affected by various circumstances. By analyzing electrodermal activity and questionnaire, we investigated the influence of five variables: (I) \textit{Realism}; (II) \textit{Question type}; (III) \textit{Interviewer attitude}; (IV) \textit{Timing}; and (V) \textit{Preparation}. As such, an orthogonal design $L_8(4^1 \times 2^4)$ with eight experiments ($O A_8$ matrix) was implemented, in which 19 college students took part in the experiments. Considering the anxiety, overall experience, and performance of the interviewees, results indicate that \textit{Question type} plays a major role; secondly, \textit{Realism}, \textit{Preparation}, and \textit{Interviewer attitude} all have some degree of influence; lastly, \textit{Timing} have little to no impact. Specifically, professional interview questions elicited a greater degree of anxiety than personal ones among the categories of interview questions. This work contributes to our understanding of anxiety-stimulating factors during job interviews in virtual reality and provides cues for designing future VRIS.

cs.HC

SMoA: Sparse Mixture of Adapters to Mitigate Multiple Dataset Biases

Recent studies reveal that various biases exist in different NLP tasks, and over-reliance on biases results in models' poor generalization ability and low adversarial robustness. To mitigate datasets biases, previous works propose lots of debiasing techniques to tackle specific biases, which perform well on respective adversarial sets but fail to mitigate other biases. In this paper, we propose a new debiasing method Sparse Mixture-of-Adapters (SMoA), which can mitigate multiple dataset biases effectively and efficiently. Experiments on Natural Language Inference and Paraphrase Identification tasks demonstrate that SMoA outperforms full-finetuning, adapter tuning baselines, and prior strong debiasing methods. Further analysis indicates the interpretability of SMoA that sub-adapter can capture specific pattern from the training data and specialize to handle specific bias.

cs.CL

Mechano-lithography: stress anisotropy driven nematic order in growing three-dimensional bacterial biofilms

Living active collectives have evolved with remarkable self-patterning ability to meet the physical and biological constraints for growth and survival. However, how complex multicellular patterns emerge from a single founder cell remains elusive. Here, by recourse to an agent-based model, we track the three-dimensional (3D) morphodynamics and cell orientational order of growing bacterial biofilms encased by agarose gels. Confined growth causes spatiotemporally heterogeneous stress buildup in the biofilm. High hydrostatic and low shear stresses at the core of the biofilm promote viscous-to-elastic transition and randomize cell packing, whereas the opposite stress state near the gel-cell interface drives nematic ordering with a time delay inherent to shear stress relaxation. Overall, stress anisotropy spatiotemporally coincides with nematic order in the confined biofilms, suggesting an anisotropic-stress-driven ordering mechanism. The strong reciprocity between stress anisotropy and cell ordering inspires innovative 3D mechano-lithography of living active collectives for a variety of environmental and biomedical applications.

physics.bio-ph

Biofilms as self-shaping growing nematics

Active nematics are the nonequilibrium analog of passive liquid crystals in which anisotropic units consume free energy to drive emergent behavior. Similar to liquid crystal (LC) molecules in displays, ordering and dynamics in active nematics are sensitive to boundary conditions; however, unlike passive liquid crystals, active nematics, such as those composed of living matter, have the potential to regulate their boundaries through self-generated stresses. Here, using bacterial biofilms confined by a hydrogel as a model system, we show how a three-dimensional, living nematic can actively shape itself and its boundary in order to regulate its internal architecture through growth-induced stresses. We show that biofilms exhibit a sharp transition in shape from domes to lenses upon changing environmental stiffness or cell-substrate friction, which is explained by a theoretical model considering the competition between confinement and interfacial forces. The growth mode defines the progression of the boundary, which in turn determines the trajectories and spatial distribution of cell lineages. We further demonstrate that the evolving boundary defines the orientational ordering of cells and the emergence of topological defects in the interior of the biofilm. Our findings reveal novel self-organization phenomena in confined active matter and provide strategies for guiding the development of programmed microbial consortia with emergent material properties.

q-bio.QM

Flow Rate Independent Multiscale Liquid Biopsy for Precision Oncology

Immunoaffinity-based liquid biopsies of circulating tumor cells (CTCs) hold great promise for cancer management, but typically suffer from low throughput, relative complexity and post-processing limitations. Here we address these issues simultaneously by decoupling and independently optimizing the nano-, micro- and macro-scales of an enrichment device that is simple to fabricate and operate. Unlike other affinity-based devices, our scalable mesh approach enables optimum capture conditions at any flow rate, as demonstrated with constant capture efficiencies, above 75% between 50-200 uL/min. The device achieved 96% sensitivity and 100% specificity when used to detect CTCs in the blood of 79 cancer patients and 20 healthy controls. We demonstrate its post processing capacity with the identification of potential responders to immune checkpoint inhibition therapy and the detection of HER2 positive breast cancer. The results compare well with other assays, including clinical standards. This suggests that our approach, which overcomes major limitations associated with affinity-based liquid biopsies, could help improve cancer management.

q-bio.QM

Less Learn Shortcut: Analyzing and Mitigating Learning of Spurious Feature-Label Correlation

Recent research has revealed that deep neural networks often take dataset biases as a shortcut to make decisions rather than understand tasks, leading to failures in real-world applications. In this study, we focus on the spurious correlation between word features and labels that models learn from the biased data distribution of training data. In particular, we define the word highly co-occurring with a specific label as biased word, and the example containing biased word as biased example. Our analysis shows that biased examples are easier for models to learn, while at the time of prediction, biased words make a significantly higher contribution to the models' predictions, and models tend to assign predicted labels over-relying on the spurious correlation between words and labels. To mitigate models' over-reliance on the shortcut (i.e. spurious correlation), we propose a training strategy Less-Learn-Shortcut (LLS): our strategy quantifies the biased degree of the biased examples and down-weights them accordingly. Experimental results on Question Matching, Natural Language Inference and Sentiment Analysis tasks show that LLS is a task-agnostic strategy and can improve the model performance on adversarial data while maintaining good performance on in-domain data.

cs.CL

Interfacial Cavitation

Cavitation has long been recognized as a crucial predictor, or precursor, to the ultimate failure of various materials, ranging from ductile metals to soft and biological materials. Traditionally, cavitation in solids is defined as an unstable expansion of a void or a defect within a material. The critical applied load needed to trigger this instability - the critical pressure - is a lengthscale independent material property and has been predicted by numerous theoretical studies for a breadth of constitutive models. While these studies usually assume that cavitation initiates from defects in the bulk of an otherwise homogeneous medium, an alternative and potentially more ubiquitous scenario can occur if the defects are found at interfaces between two distinct media within the body. Such interfaces are becoming increasingly common in modern materials with the use of multi-material composites and layer-by-layer additive manufacturing methods. However, a criterion to determine the threshold for interfacial failure, in analogy to the bulk cavitation limit, has yet to be reported. In this work we fill this gap. Our theoretical model captures a lengthscale independent limit for interfacial cavitation, and is shown to agree with our observations at two distinct lengthscales, via two different experimental systems. To further understand the competition between the two cavitation modes (bulk versus interface) we expand our investigation beyond the elastic response to understand the ensuing unstable propagation of delamination at the interface. A phase diagram summarizes these results, showing regimes in which interfacial failure becomes the dominant mechanism.

cond-mat.soft