arXiv subjects
Publications and source records attributed to Jose Gonzalez Suarez.
This research reports the entropy and information transfer throughout seven different enzymatic systems, namely, TIM-Barrel, Human Lysozyme, Ribonuclease A1, Pepsin , b-lactamase, Human Glucokinase and Carbonic anhydrase II. A general trend is detected: entropy and information is transported form the peripherical regions towards the catalytic site of the analyzed enzymatic systems.
This research reports the entropy transfer throughout the tridimensional structure of PDZ-2 and TIM barrel structures using the dynamic Gaussian Network Model. The model predicts the allocation of the allosteric pathways of the PDZ-2. Moreover. A visualization analysis reveals that entropy and information is transported towards the effector site in PDZ-2 and near to the catalytic site of the TIM-Barrel protein. The results suggest the presence of a functional hierarchy that determine information and entropy flow directionality.