arXiv subjects

Junyi Chen

Publications and source records attributed to Junyi Chen.

51 records · Page 3Linked to original sources

arXiv2024

Current Views on Mechanisms of the FLASH Effect in Cancer Radiotherapy

FLASH radiotherapy (FLASH-RT) is a new modality of radiotherapy by delivering doses with ultra-high dose rates. FLASH-RT has the ability to suppress tumor growth while sparing normal tissues, known as the FLASH effect. Although FLASH effect has proved valid in various models by different ionizing radiations, the exact underlying mechanism is still unclear. This article summarizes mainstream hypotheses of FLASH effect at physicochemical and biological levels, including oxygen depletion and free radical reactions, nuclear and mitochondria damage, as well as immune response. These hypotheses contribute reasonable explanations to the FLASH effect, and are interconnected according to the chronological order of the organism's response to ionizing radiation. By collating the existing consensus, evidence, and hypotheses, this article provides a comprehensive overview of potential mechanisms of FLASH effect and practical guidance for future investigation in the field of FLASH-RT.

physics.med-ph↗

arXiv2024

EVE: Efficient Vision-Language Pre-training with Masked Prediction and Modality-Aware MoE

Building scalable vision-language models to learn from diverse, multimodal data remains an open challenge. In this paper, we introduce an Efficient Vision-languagE foundation model, namely EVE, which is one unified multimodal Transformer pre-trained solely by one unified pre-training task. Specifically, EVE encodes both vision and language within a shared Transformer network integrated with modality-aware sparse Mixture-of-Experts (MoE) modules, which capture modality-specific information by selectively switching to different experts. To unify pre-training tasks of vision and language, EVE performs masked signal modeling on image-text pairs to reconstruct masked signals, i.e., image pixels and text tokens, given visible signals. This simple yet effective pre-training objective accelerates training by 3.5x compared to the model pre-trained with Image-Text Contrastive and Image-Text Matching losses. Owing to the combination of the unified architecture and pre-training task, EVE is easy to scale up, enabling better downstream performance with fewer resources and faster training speed. Despite its simplicity, EVE achieves state-of-the-art performance on various vision-language downstream tasks, including visual question answering, visual reasoning, and image-text retrieval.

cs.CV↗

arXiv2023

A Survey on Large Language Models for Personalized and Explainable Recommendations

In recent years, Recommender Systems(RS) have witnessed a transformative shift with the advent of Large Language Models(LLMs) in the field of Natural Language Processing(NLP). These models such as OpenAI's GPT-3.5/4, Llama from Meta, have demonstrated unprecedented capabilities in understanding and generating human-like text. This has led to a paradigm shift in the realm of personalized and explainable recommendations, as LLMs offer a versatile toolset for processing vast amounts of textual data to enhance user experiences. To provide a comprehensive understanding of the existing LLM-based recommendation systems, this survey aims to analyze how RS can benefit from LLM-based methodologies. Furthermore, we describe major challenges in Personalized Explanation Generating(PEG) tasks, which are cold-start problems, unfairness and bias problems in RS.

cs.IR↗

arXiv2023

Hierarchical-level rain image generative model based on GAN

Autonomous vehicles are exposed to various weather during operation, which is likely to trigger the performance limitations of the perception system, leading to the safety of the intended functionality (SOTIF) problems. To efficiently generate data for testing the performance of visual perception algorithms under various weather conditions, a hierarchical-level rain image generative model, rain conditional CycleGAN (RCCycleGAN), is constructed. RCCycleGAN is based on the generative adversarial network (GAN) and can generate images of light, medium, and heavy rain. Different rain intensities are introduced as labels in conditional GAN (CGAN). Meanwhile, the model structure is optimized and the training strategy is adjusted to alleviate the problem of mode collapse. In addition, natural rain images of different intensities are collected and processed for model training and validation. Compared with the two baseline models, CycleGAN and DerainCycleGAN, the peak signal-to-noise ratio (PSNR) of RCCycleGAN on the test dataset is improved by 2.58 dB and 0.74 dB, and the structural similarity (SSIM) is improved by 18% and 8%, respectively. The ablation experiments are also carried out to validate the effectiveness of the model tuning.

cs.CV↗

arXiv2023

Evolving Testing Scenario Generation Method and Intelligence Evaluation Framework for Automated Vehicles

Interaction between the background vehicles (BVs) and automated vehicles (AVs) in scenario-based testing plays a critical role in evaluating the intelligence of the AVs. Current testing scenarios typically employ predefined or scripted BVs, which inadequately reflect the complexity of human-like social behaviors in real-world driving scenarios, and also lack a systematic metric for evaluating the comprehensive intelligence of AVs. Therefore, this paper proposes an evolving scenario generation method that utilizes deep reinforcement learning (DRL) to create human-like BVs for testing and intelligence evaluation of AVs. Firstly, a class of driver models with human-like competitive, cooperative, and mutual driving motivations is designed. Then, utilizing an improved "level-k" training procedure, the three distinct driver models acquire game-based interactive driving policies. And these models are assigned to BVs for generating evolving scenarios in which all BVs can interact continuously and evolve diverse contents. Next, a framework including safety, driving efficiency, and interaction utility are presented to evaluate and quantify the intelligence performance of 3 systems under test (SUTs), indicating the effectiveness of the evolving scenario for intelligence testing. Finally, the complexity and fidelity of the proposed evolving testing scenario are validated. The results demonstrate that the proposed evolving scenario exhibits the highest level of complexity compared to other baseline scenarios and has more than 85% similarity to naturalistic driving data. This highlights the potential of the proposed method to facilitate the development and evaluation of high-level AVs in a realistic and challenging environment.

eess.SY↗

arXiv2022

PiggyBack: Pretrained Visual Question Answering Environment for Backing up Non-deep Learning Professionals

We propose a PiggyBack, a Visual Question Answering platform that allows users to apply the state-of-the-art visual-language pretrained models easily. The PiggyBack supports the full stack of visual question answering tasks, specifically data processing, model fine-tuning, and result visualisation. We integrate visual-language models, pretrained by HuggingFace, an open-source API platform of deep learning technologies; however, it cannot be runnable without programming skills or deep learning understanding. Hence, our PiggyBack supports an easy-to-use browser-based user interface with several deep learning visual language pretrained models for general users and domain experts. The PiggyBack includes the following benefits: Free availability under the MIT License, Portability due to web-based and thus runs on almost any platform, A comprehensive data creation and processing technique, and ease of use on deep learning-based visual language pretrained models. The demo video is available on YouTube and can be found at https://youtu.be/iz44RZ1lF4s.

cs.CV↗

arXiv2022

An Ontology-based Method to Identify Triggering Conditions for Perception Insufficiency of Autonomous Vehicles

The autonomous vehicle (AV) is a safety-critical system relying on complex sensors and algorithms. The AV may confront risk conditions if these sensors and algorithms misunderstand the environment and situation, even though all components are fault-free. The ISO 21448 defined the safety of the intended functionality (SOTIF), aiming to enhance the AV's safety by specifying AV's development and validation process. As required in the ISO 21448, the triggering conditions, which may lead to the vehicle's functional insufficiencies, should be analyzed and verified. However, there is not yet a method to realize a comprehensive and systematic identification of triggering conditions so far. This paper proposed an analysis framework of triggering conditions for the perception system based on the propagation chain of events model, which consists of triggering source, influenced perception stage, and triggering effect. According to the analysis framework, ontologies of triggering source and perception stage were constructed, and the relationships between concepts in ontologies are defined. According to these ontologies, triggering conditions can be generated comprehensively and systematically. The proposed method was applied on an L3 autonomous vehicle, and 20 from 87 triggering conditions identified were tested in the field, among which eight triggering conditions triggered risky behaviors of the vehicle.

eess.IV↗

arXiv2022

LAMBDA: Covering the Solution Set of Black-Box Inequality by Search Space Quantization

Black-box functions are broadly used to model complex problems that provide no explicit information but the input and output. Despite existing studies of black-box function optimization, the solution set satisfying an inequality with a black-box function plays a more significant role than only one optimum in many practical situations. Covering as much as possible of the solution set through limited evaluations to the black-box objective function is defined as the Black-Box Coverage (BBC) problem in this paper. We formalized this problem in a sample-based search paradigm and constructed a coverage criterion with Confusion Matrix Analysis. Further, we propose LAMBDA (Latent-Action Monte-Carlo Beam Search with Density Adaption) to solve BBC problems. LAMBDA can focus around the solution set quickly by recursively partitioning the search space into accepted and rejected sub-spaces. Compared with La-MCTS, LAMBDA introduces density information to overcome the sampling bias of optimization and obtain more exploration. Benchmarking shows, LAMBDA achieved state-of-the-art performance among all baselines and was at most 33x faster to get 95% coverage than Random Search. Experiments also demonstrate that LAMBDA has a promising future in the verification of autonomous systems in virtual tests.

cs.LG↗

arXiv2021

Local vaccination and systemic tumor suppression via irradiation and manganese adjuvant in mice

Presently 4T-1 luc cells were irradiated with proton under ultra-high dose rate FLASH or with gamma-ray with conventional dose rate, and then subcutaneous vaccination with or without Mn immuno-enhancing adjuvant into the mice for three times. One week later, we injected untreated 4T-1 luc cells on the other side of the vaccinated mice, and found that the untreated 4T-1 luc cells injected later nearly totally did not grow tumor (1/17) while controls without previous vaccination all grow tumors (18/18). The result is very interesting and the findings may help to explore in situ tumor vaccination as well as new combined radiotherapy strategies to effectively ablate primary and disseminated tumors. To our limited knowledge, this is the first paper reporting the high efficiency induction of systemic vaccination suppressing the metastasized/disseminated tumor progression.

physics.med-ph↗

arXiv2020

Towards an Astronomical Science Platform: Experiences and Lessons Learned from Chinese Virtual Observatory

In the era of big data astronomy, next generation telescopes and large sky surveys produce data sets at the TB or even PB level. Due to their large data volumes, these astronomical data sets are extremely difficult to transfer and analyze using personal computers or small clusters. In order to offer better access to data, data centers now generally provide online science platforms that enable analysis close to the data. The Chinese Virtual Observatory (China-VO) is one of the member projects in the International Virtual Observatory Alliance and it is dedicated to providing a research and education environment where globally distributed astronomy archives are simple to find, access, and interoperate. In this study, we summarize highlights of the work conducted at the China-VO, as well the experiences and lessons learned during the full life-cycle management of astronomical data. Finally, We discuss the challenges and future trends for astronomical science platforms.

astro-ph.IM↗

arXiv2018

Towards an Open Science Platform for the Evaluation of Data Fusion

Combining the results of different search engines in order to improve upon their performance has been the subject of many research papers. This has become known as the "Data Fusion" task, and has great promise in dealing with the vast quantity of unstructured textual data that is a feature of many Big Data scenarios. However, no universally-accepted evaluation methodology has emerged in the community. This makes it difficult to make meaningful comparisons between the various proposed techniques from reading the literature alone. Variations in the datasets, metrics, and baseline results have all contributed to this difficulty. This paper argues that a more unified approach is required, and that a centralised software platform should be developed to aid researchers in making comparisons between their algorithms and others. The desirable qualities of such a system have been identified and proposed, and an early prototype has been developed. Re-implementing algorithms published by other researchers is a great burden on those proposing new techniques. The prototype system has the potential to greatly reduce this burden and thus encourage more comparable results being generated and published more easily.

cs.IR↗

arXiv2018

A hybrid architecture for astronomical computing

With many large science equipment constructing and putting into use, astronomy has stepped into the big data era. The new method and infrastructure of big data processing has become a new requirement of many astronomers. Cloud computing, Map/Reduce, Hadoop, Spark, etc. many new technology has sprung up in recent years. Comparing to the high performance computing(HPC), Data is the center of these new technology. So, a new computing architecture infrastructure is necessary, which can be shared by both HPC and big data processing. Based on Astronomy Cloud project of Chinese Virtual Observatory (China-VO), we have made much efforts to optimize the designation of the hybrid computing platform. which include the hardware architecture, cluster management, Job and Resource scheduling.

cs.DC↗

arXiv2017

AstroCloud: A Distributed Cloud Computing and Application Platform for Astronomy

Virtual Observatory (VO) is a data-intensively online astronomical research and education environment, which takes advantages of advanced information technologies to achieve seamless and global access to astronomical information. AstroCloud is a cyber-infrastructure for astronomy research initiated by Chinese Virtual Observatory (China-VO) project, and also a kind of physical distributed platform which integrates lots of tasks such as telescope access proposal management, data archiving, data quality control, data release and open access, cloud based data processing and analysis. It consists of five application channels, i.e. observation, data, tools, cloud and public and is acting as a full lifecycle management system and gateway for astronomical data and telescopes. Physically, the platform is hosted in six cities currently, i.e. Beijing, Nanjing, Shanghai, Kunming, Lijiang and Urumqi, and serving more than 17 thousand users. Achievements from international Virtual Observatories and Cloud Computing are adopted heavily. In the paper, backgrounds of the project, architecture, Cloud Computing environment, key features of the system, current status and future plans are introduced.

astro-ph.IM↗

arXiv2016

Update of the China-VO AstroCloud

As the cyber-infrastructure for Astronomical research from Chinese Virtual Observatory (China-VO) project, AstroCloud has been archived solid progresses during the last one year. Proposal management system and data access system are re-designed. Several new sub-systems are developed, including China-VO PaperData, AstroCloud Statics and Public channel. More data sets and application environments are integrated into the platform. LAMOST DR1, the largest astronomical spectrum archive was released to the public using the platform. The latest progresses will be introduced.

astro-ph.IM↗

arXiv2014

AstroCloud, a Cyber-Infrastructure for Astronomy Research: Data Archiving and Quality Control

AstroCloud is a cyber-Infrastructure for Astronomy Research initiated by Chinese Virtual Observatory (China-VO) under funding support from NDRC (National Development and Reform commission) and CAS (Chinese Academy of Sciences){\url{http://astrocloud.china-vo.org}}\citep{O8-5_Cui_adassxxiv}. To archive the astronomical data in China, we present the implementation of the astronomical data archiving system (ADAS). Data archiving and quality control are the infrastructure for the AstroCloud. Throughout the data of the entire life cycle, data archiving system standardized data, transferring data, logging observational data, archiving ambient data, And storing these data and metadata in database. Quality control covers the whole process and all aspects of data archiving.

astro-ph.IM↗