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Kevin He

Publications and source records attributed to Kevin He.

At least 37 records · Page 2Linked to original sources

Private Private Information

Private signals model noisy information about an unknown state. Although these signals are called "private," they may still carry information about each other. Our paper introduces the concept of private private signals, which contain information about the state but not about other signals. To achieve privacy, signal quality may need to be sacrificed. We study the informativeness of private private signals and characterize those that are optimal in the sense that they cannot be made more informative without violating privacy. We discuss implications for privacy in recommendation systems, information design, causal inference, and mechanism design.

econ.TH↗

Recurrent CircuitSAT Sampling for Sequential Circuits

In this work, we introduce a novel GPU-accelerated circuit satisfiability (CircuitSAT) sampling technique for sequential circuits. This work is motivated by the requirement in constrained random verification (CRV) to generate input stimuli to validate the functionality of digital hardware circuits. A major challenge in CRV is generating inputs for sequential circuits, along with the appropriate number of clock cycles required to meet design constraints. Traditional approaches often use Boolean satisfiability (SAT) samplers to generate inputs by unrolling state transitions over a fixed number of clock cycles. However, these methods do not guarantee that a solution exists for the given number of cycles. Consequently, producing input stimuli together with the required clock cycles is essential for thorough testing and verification. Our approach converts the logical constraints and temporal behavior of sequential circuits into a recurrent CircuitSAT problem, optimized via gradient descent to efficiently explore a diverse set of valid solutions, including their associated number of clock cycles. By operating directly on the circuit structure, our method reinterprets the sampling process as a supervised multi-output regression task. This differentiable framework enables independent element-wise operations on each tensor element, facilitating parallel execution during learning. As a result, we achieve GPU-accelerated sampling with substantial runtime improvements (up to 105.1x) over state-of-the-art heuristic samplers. We demonstrate the effectiveness of our method through extensive evaluations on circuit problems from the ISCAS-89 and ITC'99 benchmark suites.

cs.AR↗

Efficient quantum tomography of a polynomial subspace

Quantum tomography is crucial for characterizing the quantum states of multipartite systems, but its practicality is often limited by the exponentially large dimension of the Hilbert space. Most existing approaches, such as compressed sensing and tensor network-based tomography, impose structural constraints on the state to enable more resource-efficient characterization. However, not all physical states can be well-approximated with highly structured states. Here, we develop a partial quantum tomography method based on direct fidelity estimation (DFE) that focuses on a neighborhood subspace -- the subspace spanned by states physically close to a given target state. Using this generalized DFE method, we estimate elements of the density operator within this subspace in a self-verifying manner. We investigate the efficiency of this approach under different sets of available measurements for various states and find that the set of available measurements significantly impacts the cost of DFE. For example, we show that Pauli measurements alone are insufficient for performing efficient DFE on all product states, whereas the full set of product measurements is sufficient. This method can be applied in many situations, including characterizing quantum systems with confined dynamics and verifying preparations of quantum states and processes.

quant-ph↗

High-Throughput SAT Sampling

In this work, we present a novel technique for GPU-accelerated Boolean satisfiability (SAT) sampling. Unlike conventional sampling algorithms that directly operate on conjunctive normal form (CNF), our method transforms the logical constraints of SAT problems by factoring their CNF representations into simplified multi-level, multi-output Boolean functions. It then leverages gradient-based optimization to guide the search for a diverse set of valid solutions. Our method operates directly on the circuit structure of refactored SAT instances, reinterpreting the SAT problem as a supervised multi-output regression task. This differentiable technique enables independent bit-wise operations on each tensor element, allowing parallel execution of learning processes. As a result, we achieve GPU-accelerated sampling with significant runtime improvements ranging from $33.6\times$ to $523.6\times$ over state-of-the-art heuristic samplers. We demonstrate the superior performance of our sampling method through an extensive evaluation on $60$ instances from a public domain benchmark suite utilized in previous studies.

cs.AI↗

DEMOTIC: A Differentiable Sampler for Multi-Level Digital Circuits

Efficient sampling of satisfying formulas for circuit satisfiability (CircuitSAT), a well-known NP-complete problem, is essential in modern front-end applications for thorough testing and verification of digital circuits. Generating such samples is a hard computational problem due to the inherent complexity of digital circuits, size of the search space, and resource constraints involved in the process. Addressing these challenges has prompted the development of specialized algorithms that heavily rely on heuristics. However, these heuristic-based approaches frequently encounter scalability issues when tasked with sampling from a larger number of solutions, primarily due to their sequential nature. Different from such heuristic algorithms, we propose a novel differentiable sampler for multi-level digital circuits, called {\sc Demotic}, that utilizes gradient descent (GD) to solve the CircuitSAT problem and obtain a wide range of valid and distinct solutions. {\sc Demotic} leverages the circuit structure of the problem instance to learn valid solutions using GD by re-framing the CircuitSAT problem as a supervised multi-output regression task. This differentiable approach allows bit-wise operations to be performed independently on each element of a tensor, enabling parallel execution of learning operations, and accordingly, GPU-accelerated sampling with significant runtime improvements compared to state-of-the-art heuristic samplers. We demonstrate the superior runtime performance of {\sc Demotic} in the sampling task across various CircuitSAT instances from the ISCAS-85 benchmark suite. Specifically, {\sc Demotic} outperforms the state-of-the-art sampler by more than two orders of magnitude in most cases.

cs.AR↗

Training-Aware Risk Control for Intensity Modulated Radiation Therapies Quality Assurance with Conformal Prediction

Measurement quality assurance (QA) practices play a key role in the safe use of Intensity Modulated Radiation Therapies (IMRT) for cancer treatment. These practices have reduced measurement-based IMRT QA failure below 1%. However, these practices are time and labor intensive which can lead to delays in patient care. In this study, we examine how conformal prediction methodologies can be used to robustly triage plans. We propose a new training-aware conformal risk control method by combining the benefit of conformal risk control and conformal training. We incorporate the decision making thresholds based on the gamma passing rate, along with the risk functions used in clinical evaluation, into the design of the risk control framework. Our method achieves high sensitivity and specificity and significantly reduces the number of plans needing measurement without generating a huge confidence interval. Our results demonstrate the validity and applicability of conformal prediction methods for improving efficiency and reducing the workload of the IMRT QA process.

cs.LG↗

Screening $p$-Hackers: Dissemination Noise as Bait

We show that adding noise before publishing data effectively screens $p$-hacked findings: spurious explanations produced by fitting many statistical models (data mining). Noise creates "baits" that affect two types of researchers differently. Uninformed $p$-hackers, who are fully ignorant of the true mechanism and engage in data mining, often fall for baits. Informed researchers, who start with an ex-ante hypothesis, are minimally affected. We show that as the number of observations grows large, dissemination noise asymptotically achieves optimal screening. In a tractable special case where the informed researchers' theory can identify the true causal mechanism with very little data, we characterize the optimal level of dissemination noise and highlight the relevant trade-offs. Dissemination noise is a tool that statistical agencies currently use to protect privacy. We argue this existing practice can be repurposed to screen $p$-hackers and thus improve research credibility.

econ.TH↗

Direct Collocation for Quantum Optimal Control

We present an adaptation of direct collocation -- a trajectory optimization method commonly used in robotics and aerospace applications -- to quantum optimal control (QOC); we refer to this method as Pade Integrator COllocation (PICO). This approach supports general nonlinear constraints on the states and controls, takes advantage of state-of-the-art large-scale nonlinear programming solvers, and has superior convergence properties compared to standard approaches like GRAPE and CRAB. PICO also allows for the formulation of novel free-time and minimum-time control problems -- crucial for realizing high-performance quantum computers when the optimal pulse duration is not known a priori. We demonstrate PICO's performance both in simulation and on hardware with a 3D circuit cavity quantum electrodynamics system.

quant-ph↗

Efficient multimode Wigner tomography

Advancements in quantum system lifetimes and control have enabled the creation of increasingly complex quantum states, such as those on multiple bosonic cavity modes. When characterizing these states, traditional tomography scales exponentially in both computational and experimental measurement requirement, which becomes prohibitive as the state size increases. Here, we implement a state reconstruction method whose sampling requirement instead scales polynomially with subspace size, and thus mode number, for states that can be expressed within such a subspace. We demonstrate this improved scaling with Wigner tomography of multimode entangled W states of up to 4 modes on a 3D circuit quantum electrodynamics (cQED) system. This approach performs similarly in efficiency to existing matrix inversion methods for 2 modes, and demonstrates a noticeable improvement for 3 and 4 modes, with even greater theoretical gains at higher mode numbers.

quant-ph↗

Robust Privacy-Preserving Models for Cluster-Level Confounding: Recognizing Disparities in Access to Transplantation

In applications where the study data are collected within cluster units (e.g., patients within transplant centers), it is often of interest to estimate and perform inference on the treatment effects of the cluster units. However, it is well-established that cluster-level confounding variables can bias these assessments, and many of these confounding factors may be unobservable. In healthcare settings, data sharing restrictions often make it impossible to directly fit conventional risk-adjustment models on patient-level data, and existing privacy-preserving approaches cannot adequately adjust for both observed and unobserved cluster-level confounding factors. In this paper, we propose a privacy-preserving model for cluster-level confounding that only depends on publicly-available summary statistics, can be fit using a single optimization routine, and is robust to outlying cluster unit effects. In addition, we develop a Pseudo-Bayesian inference procedure that accounts for the estimated cluster-level confounding effects and corrects for the impact of unobservable factors. Simulations show that our estimates are robust and accurate, and the proposed inference approach has better Frequentist properties than existing methods. Motivated by efforts to improve equity in transplant care, we apply these methods to evaluate transplant centers while adjusting for observed geographic disparities in donor organ availability and unobservable confounders.

stat.AP↗

Stimulated emission of signal photons from dark matter waves

The manipulation of quantum states of light has resulted in significant advancements in both dark matter searches and gravitational wave detectors [1-4]. Current dark matter searches operating in the microwave frequency range use nearly quantum-limited amplifiers [3, 5, 6]. Future high frequency searches will use photon counting techniques [1] to evade the standard quantum limit. We present a signal enhancement technique that utilizes a superconducting qubit to prepare a superconducting microwave cavity in a non-classical Fock state and stimulate the emission of a photon from a dark matter wave. By initializing the cavity in an $|n=4\rangle$ Fock state, we demonstrate a quantum enhancement technique that increases the signal photon rate and hence also the dark matter scan rate each by a factor of 2.78. Using this technique, we conduct a dark photon search in a band around $\mathrm{5.965\, GHz \, (24.67\, μeV)}$, where the kinetic mixing angle $ε\geq 4.35 \times 10^{-13}$ is excluded at the $90\%$ confidence level.

quant-ph↗

KL-divergence Based Deep Learning for Discrete Time Model

Neural Network (Deep Learning) is a modern model in Artificial Intelligence and it has been exploited in Survival Analysis. Although several improvements have been shown by previous works, training an excellent deep learning model requires a huge amount of data, which may not hold in practice. To address this challenge, we develop a Kullback-Leibler-based (KL) deep learning procedure to integrate external survival prediction models with newly collected time-to-event data. Time-dependent KL discrimination information is utilized to measure the discrepancy between the external and internal data. This is the first work considering using prior information to deal with short data problem in Survival Analysis for deep learning. Simulation and real data results show that the proposed model achieves better performance and higher robustness compared with previous works.

stat.ML↗

Incorporating External Risk Information with the Cox Model under Population Heterogeneity: Applications to Trans-Ancestry Polygenic Hazard Scores

Polygenic hazard score (PHS) models designed for European ancestry (EUR) individuals provide ample information regarding survival risk discrimination. Incorporating such information can improve the performance of risk discrimination in an internal small-sized non-EUR cohort. However, given that external EUR-based model and internal individual-level data come from different populations, ignoring population heterogeneity can introduce substantial bias. In this paper, we develop a Kullback-Leibler-based Cox model (CoxKL) to integrate internal individual-level time-to-event data with external risk scores derived from published prediction models, accounting for population heterogeneity. Partial-likelihood-based KL information is utilized to measure the discrepancy between the external risk information and the internal data. We establish the asymptotic properties of the CoxKL estimator. Simulation studies show that the integration model by the proposed CoxKL method achieves improved estimation efficiency and prediction accuracy. We applied the proposed method to develop a trans-ancestry PHS model for prostate cancer and found that integrating a previously published EUR-based PHS with an internal genotype data of African ancestry (AFR) males yielded considerable improvement on the prostate cancer risk discrimination.

stat.ME↗

Evolutionarily Stable (Mis)specifications: Theory and Applications

Toward explaining the persistence of biased inferences, we propose a framework to evaluate competing (mis)specifications in strategic settings. Agents with heterogeneous (mis)specifications coexist and draw Bayesian inferences about their environment through repeated play. The relative stability of (mis)specifications depends on their adherents' equilibrium payoffs. A key mechanism is the learning channel: the endogeneity of perceived best replies due to inference. We characterize when a rational society is only vulnerable to invasion by some misspecification through the learning channel. The learning channel leads to new stability phenomena, and can confer an evolutionary advantage to otherwise detrimental biases in economically relevant applications.

econ.TH↗

Dynamic Information Design with Diminishing Sensitivity Over News

A Bayesian agent experiences gain-loss utility each period over changes in belief about future consumption ("news utility"), with diminishing sensitivity over the magnitude of news. Diminishing sensitivity induces a preference over news skewness: gradual bad news, one-shot good news is worse than one-shot resolution, which is in turn worse than gradual good news, one-shot bad news. So, the agent's preference between gradual information and one-shot resolution can depend on his consumption ranking of different states. In a dynamic cheap-talk framework where a benevolent sender communicates the state over multiple periods, the babbling equilibrium is essentially unique without loss aversion. More loss-averse agents may enjoy higher news utility in equilibrium, contrary to the commitment case. We characterize the family of gradual good news equilibria that exist with high enough loss aversion, and find the sender conveys progressively larger pieces of good news. We discuss applications to media competition and game shows.

econ.TH↗

Bregman Divergence-Based Data Integration with Application to Polygenic Risk Score (PRS) Heterogeneity Adjustment

Polygenic risk scores (PRS) have recently received much attention for genetics risk prediction. While successful for the Caucasian population, the PRS based on the minority population suffer from small sample sizes, high dimensionality and low signal-to-noise ratios, exacerbating already severe health disparities. Due to population heterogeneity, direct trans-ethnic prediction by utilizing the Caucasian model for the minority population also has limited performance. In addition, due to data privacy, the individual genotype data is not accessible for either the Caucasian population or the minority population. To address these challenges, we propose a Bregman divergence-based estimation procedure to measure and optimally balance the information from different populations. The proposed method only requires the use of encrypted summary statistics and improves the PRS performance for ethnic minority groups by incorporating additional information. We provide the asymptotic consistency and weak oracle property for the proposed method. Simulations and real data analyses also show its advantages in prediction and variable selection.

stat.ME↗

Understanding the dynamic impact of COVID-19 through competing risk modeling with bivariate varying coefficients

The coronavirus disease 2019 (COVID-19) pandemic has exerted a profound impact on patients with end-stage renal disease relying on kidney dialysis to sustain their lives. Motivated by a request by the U.S. Centers for Medicare & Medicaid Services, our analysis of their postdischarge hospital readmissions and deaths in 2020 revealed that the COVID-19 effect has varied significantly with postdischarge time and time since the onset of the pandemic. However, the complex dynamics of the COVID-19 effect trajectories cannot be characterized by existing varying coefficient models. To address this issue, we propose a bivariate varying coefficient model for competing risks within a cause-specific hazard framework, where tensor-product B-splines are used to estimate the surface of the COVID-19 effect. An efficient proximal Newton algorithm is developed to facilitate the fitting of the new model to the massive Medicare data for dialysis patients. Difference-based anisotropic penalization is introduced to mitigate model overfitting and the wiggliness of the estimated trajectories; various cross-validation methods are considered in the determination of optimal tuning parameters. Hypothesis testing procedures are designed to examine whether the COVID-19 effect varies significantly with postdischarge time and the time since pandemic onset, either jointly or separately. Simulation experiments are conducted to evaluate the estimation accuracy, type I error rate, statistical power, and model selection procedures. Applications to Medicare dialysis patients demonstrate the real-world performance of the proposed methods.

stat.ME↗

Kullback-Leibler-Based Discrete Failure Time Models for Integration of Published Prediction Models with New Time-To-Event Dataset

Prediction of time-to-event data often suffers from rare event rates, small sample sizes, high dimensionality and low signal-to-noise ratios. Incorporating published prediction models from large-scale studies is expected to improve the performance of prognosis prediction on internal individual-level time-to-event data. However, existing integration approaches typically assume that underlying distributions from the external and internal data sources are similar, which is often invalid. To account for challenges including heterogeneity, data sharing, and privacy constraints, we propose a discrete failure time modeling procedure, which utilizes a discrete hazard-based Kullback-Leibler discriminatory information measuring the discrepancy between the published models and the internal dataset. Simulations show the advantage of the proposed method compared with those solely based on the internal data or published models. We apply the proposed method to improve prediction performance on a kidney transplant dataset from a local hospital by integrating this small-scale dataset with published survival models obtained from the national transplant registry.

stat.ME↗