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Li Lin

Publications and source records attributed to Li Lin.

At least 91 records · Page 5Linked to original sources

Semantic Enhanced Text-to-SQL Parsing via Iteratively Learning Schema Linking Graph

The generalizability to new databases is of vital importance to Text-to-SQL systems which aim to parse human utterances into SQL statements. Existing works achieve this goal by leveraging the exact matching method to identify the lexical matching between the question words and the schema items. However, these methods fail in other challenging scenarios, such as the synonym substitution in which the surface form differs between the corresponding question words and schema items. In this paper, we propose a framework named ISESL-SQL to iteratively build a semantic enhanced schema-linking graph between question tokens and database schemas. First, we extract a schema linking graph from PLMs through a probing procedure in an unsupervised manner. Then the schema linking graph is further optimized during the training process through a deep graph learning method. Meanwhile, we also design an auxiliary task called graph regularization to improve the schema information mentioned in the schema-linking graph. Extensive experiments on three benchmarks demonstrate that ISESL-SQL could consistently outperform the baselines and further investigations show its generalizability and robustness.

cs.CL

AADG: Automatic Augmentation for Domain Generalization on Retinal Image Segmentation

Convolutional neural networks have been widely applied to medical image segmentation and have achieved considerable performance. However, the performance may be significantly affected by the domain gap between training data (source domain) and testing data (target domain). To address this issue, we propose a data manipulation based domain generalization method, called Automated Augmentation for Domain Generalization (AADG). Our AADG framework can effectively sample data augmentation policies that generate novel domains and diversify the training set from an appropriate search space. Specifically, we introduce a novel proxy task maximizing the diversity among multiple augmented novel domains as measured by the Sinkhorn distance in a unit sphere space, making automated augmentation tractable. Adversarial training and deep reinforcement learning are employed to efficiently search the objectives. Quantitative and qualitative experiments on 11 publicly-accessible fundus image datasets (four for retinal vessel segmentation, four for optic disc and cup (OD/OC) segmentation and three for retinal lesion segmentation) are comprehensively performed. Two OCTA datasets for retinal vasculature segmentation are further involved to validate cross-modality generalization. Our proposed AADG exhibits state-of-the-art generalization performance and outperforms existing approaches by considerable margins on retinal vessel, OD/OC and lesion segmentation tasks. The learned policies are empirically validated to be model-agnostic and can transfer well to other models. The source code is available at https://github.com/CRazorback/AADG.

eess.IV

Transcranial photoacoustic computed tomography of human brain function

Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a hemicraniectomy patient. The observed brain responses in these preliminary results demonstrate the potential of photoacoustic computed tomography for achieving transcranial functional imaging.

physics.med-ph

A Multi-level Supervised Contrastive Learning Framework for Low-Resource Natural Language Inference

Natural Language Inference (NLI) is a growingly essential task in natural language understanding, which requires inferring the relationship between the sentence pairs (premise and hypothesis). Recently, low-resource natural language inference has gained increasing attention, due to significant savings in manual annotation costs and a better fit with real-world scenarios. Existing works fail to characterize discriminative representations between different classes with limited training data, which may cause faults in label prediction. Here we propose a multi-level supervised contrastive learning framework named MultiSCL for low-resource natural language inference. MultiSCL leverages a sentence-level and pair-level contrastive learning objective to discriminate between different classes of sentence pairs by bringing those in one class together and pushing away those in different classes. MultiSCL adopts a data augmentation module that generates different views for input samples to better learn the latent representation. The pair-level representation is obtained from a cross attention module. We conduct extensive experiments on two public NLI datasets in low-resource settings, and the accuracy of MultiSCL exceeds other models by 3.1% on average. Moreover, our method outperforms the previous state-of-the-art method on cross-domain tasks of text classification.

cs.CL

Pair-Level Supervised Contrastive Learning for Natural Language Inference

Natural language inference (NLI) is an increasingly important task for natural language understanding, which requires one to infer the relationship between the sentence pair (premise and hypothesis). Many recent works have used contrastive learning by incorporating the relationship of the sentence pair from NLI datasets to learn sentence representation. However, these methods only focus on comparisons with sentence-level representations. In this paper, we propose a Pair-level Supervised Contrastive Learning approach (PairSCL). We adopt a cross attention module to learn the joint representations of the sentence pairs. A contrastive learning objective is designed to distinguish the varied classes of sentence pairs by pulling those in one class together and pushing apart the pairs in other classes. We evaluate PairSCL on two public datasets of NLI where the accuracy of PairSCL outperforms other methods by 2.1% on average. Furthermore, our method outperforms the previous state-of-the-art method on seven transfer tasks of text classification.

cs.CL

DS3-Net: Difficulty-perceived Common-to-T1ce Semi-Supervised Multimodal MRI Synthesis Network

Contrast-enhanced T1 (T1ce) is one of the most essential magnetic resonance imaging (MRI) modalities for diagnosing and analyzing brain tumors, especially gliomas. In clinical practice, common MRI modalities such as T1, T2, and fluid attenuation inversion recovery are relatively easy to access while T1ce is more challenging considering the additional cost and potential risk of allergies to the contrast agent. Therefore, it is of great clinical necessity to develop a method to synthesize T1ce from other common modalities. Current paired image translation methods typically have the issue of requiring a large amount of paired data and do not focus on specific regions of interest, e.g., the tumor region, in the synthesization process. To address these issues, we propose a Difficulty-perceived common-to-T1ce Semi-Supervised multimodal MRI Synthesis network (DS3-Net), involving both paired and unpaired data together with dual-level knowledge distillation. DS3-Net predicts a difficulty map to progressively promote the synthesis task. Specifically, a pixelwise constraint and a patchwise contrastive constraint are guided by the predicted difficulty map. Through extensive experiments on the publiclyavailable BraTS2020 dataset, DS3-Net outperforms its supervised counterpart in each respect. Furthermore, with only 5% paired data, the proposed DS3-Net achieves competitive performance with state-of-theart image translation methods utilizing 100% paired data, delivering an average SSIM of 0.8947 and an average PSNR of 23.60.

eess.IV

Uni4Eye: Unified 2D and 3D Self-supervised Pre-training via Masked Image Modeling Transformer for Ophthalmic Image Classification

A large-scale labeled dataset is a key factor for the success of supervised deep learning in computer vision. However, a limited number of annotated data is very common, especially in ophthalmic image analysis, since manual annotation is time-consuming and labor-intensive. Self-supervised learning (SSL) methods bring huge opportunities for better utilizing unlabeled data, as they do not need massive annotations. With an attempt to use as many as possible unlabeled ophthalmic images, it is necessary to break the dimension barrier, simultaneously making use of both 2D and 3D images. In this paper, we propose a universal self-supervised Transformer framework, named Uni4Eye, to discover the inherent image property and capture domain-specific feature embedding in ophthalmic images. Uni4Eye can serve as a global feature extractor, which builds its basis on a Masked Image Modeling task with a Vision Transformer (ViT) architecture. We employ a Unified Patch Embedding module to replace the origin patch embedding module in ViT for jointly processing both 2D and 3D input images. Besides, we design a dual-branch multitask decoder module to simultaneously perform two reconstruction tasks on the input image and its gradient map, delivering discriminative representations for better convergence. We evaluate the performance of our pre-trained Uni4Eye encoder by fine-tuning it on six downstream ophthalmic image classification tasks. The superiority of Uni4Eye is successfully established through comparisons to other state-of-the-art SSL pre-training methods.

eess.IV

Multi-modal Brain Tumor Segmentation via Missing Modality Synthesis and Modality-level Attention Fusion

Multi-modal magnetic resonance (MR) imaging provides great potential for diagnosing and analyzing brain gliomas. In clinical scenarios, common MR sequences such as T1, T2 and FLAIR can be obtained simultaneously in a single scanning process. However, acquiring contrast enhanced modalities such as T1ce requires additional time, cost, and injection of contrast agent. As such, it is clinically meaningful to develop a method to synthesize unavailable modalities which can also be used as additional inputs to downstream tasks (e.g., brain tumor segmentation) for performance enhancing. In this work, we propose an end-to-end framework named Modality-Level Attention Fusion Network (MAF-Net), wherein we innovatively conduct patchwise contrastive learning for extracting multi-modal latent features and dynamically assigning attention weights to fuse different modalities. Through extensive experiments on BraTS2020, our proposed MAF-Net is found to yield superior T1ce synthesis performance (SSIM of 0.8879 and PSNR of 22.78) and accurate brain tumor segmentation (mean Dice scores of 67.9%, 41.8% and 88.0% on segmenting the tumor core, enhancing tumor and whole tumor).

eess.IV

JOINED : Prior Guided Multi-task Learning for Joint Optic Disc/Cup Segmentation and Fovea Detection

Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and optic cup (OC) are important anatomical landmarks. Identification of those anatomical landmarks is of great clinical importance. However, the presence of lesions, drusen, and other abnormalities during retinal degeneration severely complicates automatic landmark detection and segmentation. Most existing works treat the identification of each landmark as a single task and typically do not make use of any clinical prior information. In this paper, we present a novel method, named JOINED, for prior guided multi-task learning for joint OD/OC segmentation and fovea detection. An auxiliary branch for distance prediction, in addition to a segmentation branch and a detection branch, is constructed to effectively utilize the distance information from each image pixel to landmarks of interest. Our proposed JOINED pipeline consists of a coarse stage and a fine stage. At the coarse stage, we obtain the OD/OC coarse segmentation and the heatmap localization of fovea through a joint segmentation and detection module. Afterwards, we crop the regions of interest for subsequent fine processing and use predictions obtained at the coarse stage as additional information for better performance and faster convergence. Experimental results reveal that our proposed JOINED outperforms existing state-of-the-art approaches on the publicly-available GAMMA, PALM, and REFUGE datasets of fundus images. Furthermore, JOINED ranked the 5th on the OD/OC segmentation and fovea detection tasks in the GAMMA challenge hosted by the MICCAI2021 workshop OMIA8.

eess.IV

COROLLA: An Efficient Multi-Modality Fusion Framework with Supervised Contrastive Learning for Glaucoma Grading

Glaucoma is one of the ophthalmic diseases that may cause blindness, for which early detection and treatment are very important. Fundus images and optical coherence tomography (OCT) images are both widely-used modalities in diagnosing glaucoma. However, existing glaucoma grading approaches mainly utilize a single modality, ignoring the complementary information between fundus and OCT. In this paper, we propose an efficient multi-modality supervised contrastive learning framework, named COROLLA, for glaucoma grading. Through layer segmentation as well as thickness calculation and projection, retinal thickness maps are extracted from the original OCT volumes and used as a replacing modality, resulting in more efficient calculations with less memory usage. Given the high structure and distribution similarities across medical image samples, we employ supervised contrastive learning to increase our models' discriminative power with better convergence. Moreover, feature-level fusion of paired fundus image and thickness map is conducted for enhanced diagnosis accuracy. On the GAMMA dataset, our COROLLA framework achieves overwhelming glaucoma grading performance compared to state-of-the-art methods.

eess.IV

Unsupervised Domain Adaptation for Cross-Modality Retinal Vessel Segmentation via Disentangling Representation Style Transfer and Collaborative Consistency Learning

Various deep learning models have been developed to segment anatomical structures from medical images, but they typically have poor performance when tested on another target domain with different data distribution. Recently, unsupervised domain adaptation methods have been proposed to alleviate this so-called domain shift issue, but most of them are designed for scenarios with relatively small domain shifts and are likely to fail when encountering a large domain gap. In this paper, we propose DCDA, a novel cross-modality unsupervised domain adaptation framework for tasks with large domain shifts, e.g., segmenting retinal vessels from OCTA and OCT images. DCDA mainly consists of a disentangling representation style transfer (DRST) module and a collaborative consistency learning (CCL) module. DRST decomposes images into content components and style codes and performs style transfer and image reconstruction. CCL contains two segmentation models, one for source domain and the other for target domain. The two models use labeled data (together with the corresponding transferred images) for supervised learning and perform collaborative consistency learning on unlabeled data. Each model focuses on the corresponding single domain and aims to yield an expertized domain-specific segmentation model. Through extensive experiments on retinal vessel segmentation, our framework achieves Dice scores close to target-trained oracle both from OCTA to OCT and from OCT to OCTA, significantly outperforming other state-of-the-art methods.

eess.IV

Gradient Imitation Reinforcement Learning for Low Resource Relation Extraction

Low-resource Relation Extraction (LRE) aims to extract relation facts from limited labeled corpora when human annotation is scarce. Existing works either utilize self-training scheme to generate pseudo labels that will cause the gradual drift problem, or leverage meta-learning scheme which does not solicit feedback explicitly. To alleviate selection bias due to the lack of feedback loops in existing LRE learning paradigms, we developed a Gradient Imitation Reinforcement Learning method to encourage pseudo label data to imitate the gradient descent direction on labeled data and bootstrap its optimization capability through trial and error. We also propose a framework called GradLRE, which handles two major scenarios in low-resource relation extraction. Besides the scenario where unlabeled data is sufficient, GradLRE handles the situation where no unlabeled data is available, by exploiting a contextualized augmentation method to generate data. Experimental results on two public datasets demonstrate the effectiveness of GradLRE on low resource relation extraction when comparing with baselines.

cs.CL

Bohmian Trajectories of the Time-oscillating Schrödinger Equations

Bohmian mechanics is a non-relativistic quantum theory based on a particle approach. In this paper we study the Schrödinger equation with rapidly oscillating potential and the associated Bohmian trajectory. We prove that the corresponding Bohmian trajectory converges locally in measure, and the limit coincides with the Bohmian trajectory for the effective Schrödinger equation on a finite time interval. This is beneficial for the efficient simulation of the Bohmian trajectories in oscillating potential fields.

math-ph

An Intelligent Material with Chemical Pathway Networks

A new type of material with embedded intelligence, namely 'intelligent plasma', is introduced. Such new material exhibits programmable chemical pathway networks resembling artificial neural networks. As a Markov process of chemistry, the chemical pathway network can be customized and thus the intelligent plasmas can be programmed to make their own decisions to react to the dynamic external and internal conditions. It finally can accomplish complex missions without any external controls from the humans while relying on its preprogrammed chemical network topology before the mission. To that end, only basic data input and readings are required without any external controls during the mission. The approach to 'if' conditions and 'while' loops of the programmable intelligent plasmas are also discussed with examples of applications including automatic workflows, and signal processing.

cs.ET

Lesion-based Contrastive Learning for Diabetic Retinopathy Grading from Fundus Images

Manually annotating medical images is extremely expensive, especially for large-scale datasets. Self-supervised contrastive learning has been explored to learn feature representations from unlabeled images. However, unlike natural images, the application of contrastive learning to medical images is relatively limited. In this work, we propose a self-supervised framework, namely lesion-based contrastive learning for automated diabetic retinopathy (DR) grading. Instead of taking entire images as the input in the common contrastive learning scheme, lesion patches are employed to encourage the feature extractor to learn representations that are highly discriminative for DR grading. We also investigate different data augmentation operations in defining our contrastive prediction task. Extensive experiments are conducted on the publicly-accessible dataset EyePACS, demonstrating that our proposed framework performs outstandingly on DR grading in terms of both linear evaluation and transfer capacity evaluation.

cs.CV

BSDA-Net: A Boundary Shape and Distance Aware Joint Learning Framework for Segmenting and Classifying OCTA Images

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging technique that allows visualizations of vasculature and foveal avascular zone (FAZ) across retinal layers. Clinical researches suggest that the morphology and contour irregularity of FAZ are important biomarkers of various ocular pathologies. Therefore, precise segmentation of FAZ has great clinical interest. Also, there is no existing research reporting that FAZ features can improve the performance of deep diagnostic classification networks. In this paper, we propose a novel multi-level boundary shape and distance aware joint learning framework, named BSDA-Net, for FAZ segmentation and diagnostic classification from OCTA images. Two auxiliary branches, namely boundary heatmap regression and signed distance map reconstruction branches, are constructed in addition to the segmentation branch to improve the segmentation performance, resulting in more accurate FAZ contours and fewer outliers. Moreover, both low-level and high-level features from the aforementioned three branches, including shape, size, boundary, and signed directional distance map of FAZ, are fused hierarchically with features from the diagnostic classifier. Through extensive experiments, the proposed BSDA-Net is found to yield state-of-the-art segmentation and classification results on the OCTA-500, OCTAGON, and FAZID datasets.

eess.IV

Dynamical behavior of a nonlocal Fokker-Planck equation for a stochastic system with tempered stable noise

We characterize a stochastic dynamical system with tempered stable noise, by examining its probability density evolution. This probability density function satisfies a nonlocal Fokker-Planck equation. First, we prove a superposition principle that the probability measure-valued solution to this nonlocal Fokker-Planck equation is equivalent to the martingale solution composed with the inverse stochastic flow. This result together with a Schauder estimate leads to the existence and uniqueness of strong solution for the nonlocal Fokker-Planck equation. Second, we devise a convergent finite difference method to simulate the probability density function by solving the nonlocal Fokker-Planck equation. Finally, we apply our aforementioned theoretical and numerical results to a nonlinear filtering system by simulating a nonlocal Zakai equation.

math.DS

Convergence rate for homogenization of a nonlocal model with oscillating coefficients

This letter deals with homogenization of a nonlocal model with Levy-type operator of rapidly oscillating coefficients. This nonlocal model describes mean residence time and other escape phenomena for stochastic dynamical systems with non-Gaussian Levy noise. We derive an effective model with a specific convergence rate. This enables efficient analysis and simulation of escape phenomena under non-Gaussian fluctuations.

math.FA