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Li Shen

Publications and source records attributed to Li Shen.

At least 19 recordsLinked to original sources

Robust Community Detection for Noisy Networks with Covariates: Application to Functional Brain Networks

Community detection is fundamental to understanding the modular organization in functional brain networks, yet noise in neuroimaging-derived networks and auxiliary node-level covariates pose critical challenges. Existing methods typically either assume networks are noise-free or ignore covariate information. We propose a Bayesian framework for recovering a shared latent community structure from multiple noisy network realizations and auxiliary covariates. The model combines a degree-corrected stochastic block model for the latent network, a block-structured noise model linking noisy observations to latent edges, and a covariate cluster model for node-level attributes. This specification allows anatomical or functional attributes of regions of interest to contribute information when network signals are weak or sparse. We develop an efficient Markov chain Monte Carlo algorithm for posterior sampling and select the number of communities using the widely applicable information criterion, avoiding prior specification of this quantity. Simulation studies demonstrate improved community recovery relative to existing methods across varying noise levels, covariate signal strengths, and numbers of noisy networks, with larger gains when network noise is moderate to high or only a small number of noisy networks is available. Applications to functional brain networks from the Alzheimer's Disease Neuroimaging Initiative and the Human Connectome Project identify biologically interpretable structures and capture disease-related reorganization and individual-level variation.

stat.ME

Knowledge Acquisition During Pre-training? Large Language Models Learn Better With Auxiliary Views

Gaps remain in our understanding of how large language models (LLMs) acquire knowledge during pre-training. We posit that auxiliary views, reformulations of knowledge, are causally helpful for learning. We design controlled experiments to isolate this. First, we confirm that repetition is necessary for acquisition and clarify that paraphrasing helps only at smaller batch sizes. Second, holding the token budget fixed, allocating tokens from document repetition to auxiliary views improves learning, counterintuitively, even for factual recall. Third, the effectiveness of auxiliary views is not contingent on the strength of the teacher model that generates them. Fourth, we identify forms of knowledge, contextual and foundational, that aid learning in the presence of prior knowledge gaps. Finally, we examine how these effects manifest mechanistically via layer-wise biases and compression. Together, our findings suggest that auxiliary representations of knowledge, which arise naturally in large pre-training corpora, are a key factor in the success of pre-training and offer a plausible explanation for why data diversity matters.

cs.CL

Auditable CT Phenotyping Through Report-derived Radiological Observations

Medical image foundation models can predict clinical phenotypes from computed tomography (CT), but strong performance leaves open whether they read disease-specific findings or shortcuts that correlate with the diagnosis. We tested this in 221 electronic-health-record (EHR) phenotypes using Auditable CT phenotyping (ACT), built on report-derived radiological observations. We trained ACT on 38,317 patients, mined 376,194 observations and evaluated it in 25,183 held-out patients. ACT exceeded five vision-language baselines on zero-shot annotation, and CT-CLIP across 221 phenotypes from unseen CT pulmonary angiography, both under zero-shot scoring (0.651 versus 0.572) and under linear probing (0.709 versus 0.662). Reading each probe exposes what accuracy conceals: only 97 observations occupy the 221 rank-1 positions, and one phrase describing aortic and coronary calcification ranks first for 20 phenotypes, including osteoporosis, urinary tract infection and major depressive disorder. Restricting the bank to clinician-specified evidence redirects those probes onto phenotype-related observations in 86 phenotypes at no accuracy cost (0.751 versus 0.741). Accurate CT-based EHR phenotyping can therefore rest on observations that are not valid evidence for the coded phenotype and that ACT can identify and intervene on.

cs.CV

GenFAR: A generalized representation of brain structure, derived from 49,246 multi-cohort MRIs via deep learning

Deep learning models for neuroimaging have largely been developed for individual tasks, limiting knowledge transfer across applications. Here we introduce GenFAR, a modular deep learning framework that learns general, clinically informed features from brain MRIs. We trained this modular architecture on 49,246 individuals across 11 cohorts, using 17 diverse classification and regression tasks spanning cognition, clinical, diagnosis, demographics, and biomarkers. This yields aggregated, focused feature sets that capture rich, clinically- and biologically-relevant brain representations. We developed a sequential learning approach where tasks progressively build on previously learned representations. Through an analysis of 5,000 task sequences, we identified an optimal sequence length of six tasks and introduced a Donor Score metric to quantify each task's contribution to downstream performance. This analysis revealed five consistently strong donor tasks (Age, AD/MCI, MMSE, Hypertension, Hyperlipidemia) that formed the base of our sequential model. We demonstrated the utility of our learned representation, in various tasks beyond those included in the training set, to serve as the foundation for specialized secondary predictors. We further showed that using the learned feature representation can substantially increase the sample efficiency of secondary deep learning training tasks and models, as well as improve their accuracy.

cs.CV

Invertible Logits Transformation for Accuracy-Preserving Post-Hoc Uncertainty Calibration

Post-hoc calibration aligns a classifier's predicted confidences with its empirical accuracy without retraining. An ideal calibrator should correct nonlinear miscalibration, scale gracefully to large label spaces, and preserve the original predictions; existing methods typically violate at least one of these properties---temperature scaling lacks expressivity, more flexible parametric alternatives introduce parameters that grow with the number of classes $C$, and other expressive methods do not preserve the rank ordering of class scores and may alter the predicted class. We propose \textbf{Invertible Logits Transformation (InvLT)}, which applies a learned scalar MLP $f:\mathbb{R}\to\mathbb{R}$ element-wise to the pre-softmax logits. Sharing $f$ across all logit dimensions makes the parameter count independent of $C$. Monotonicity of $f$---and hence preservation of the argmax prediction---is softly encouraged via a paired inverse network rather than enforced through the numerical integration required by prior monotone calibrators; this avoids their computational overhead while empirically preserving the original classification accuracy in every setting we evaluate. Across standard image classification benchmarks and a range of architectures, InvLT consistently outperforms a broad set of post-hoc baselines on standard calibration metrics.

cs.LG

VFAD: Variational Semantic Prompting Meets Frequency-Adaptive Representation Learning for Zero-Shot Anomaly Detection

Zero-shot anomaly detection (ZSAD) aims to detect and localize anomalies in unseen categories without access to target-specific training data. Although recent CLIP-based methods have demonstrated promising generalization through vision-language alignment, they remain limited in capturing diverse anomaly semantics and subtle local variations. To address these limitations, we propose VFAD, a unified framework that combines variational semantic prompting with frequency-adaptive representation learning. Specifically, we introduce a Variational Semantic Prompt Extractor (VSPE), which adaptively aggregates anomaly-relevant local semantics from dense patch tokens and regularizes them through a variational information bottleneck, thereby incorporating fine-grained visual cues and enabling more precise cross-modal alignment. Furthermore, we develop a Frequency-Adaptive Representation Aggregation (FARA) module that leverages wavelet-based frequency decomposition and frequency-specific expert aggregation to enhance anomaly-discriminative visual representations. By jointly strengthening semantic guidance and visual representation learning, VFAD improves both anomaly discrimination and fine-grained localization. Extensive experiments on 13 industrial and medical benchmarks demonstrate that VFAD consistently outperforms existing state-of-the-art ZSAD methods across diverse anomaly scenarios. The code will be publicly available upon publication.

cs.CV

ExToken: Structured Exploration for Efficient Vision-Language-Action Reinforcement Fine-tuning

Reinforcement Learning (RL) has demonstrated significant potential for improving Vision-Language-Action (VLA) models on complex manipulation tasks. However, its practical scalability remains severely limited by the substantial cost of environmental interactions. In this work, we first investigate the exploration stagnation bottleneck in current VLA-RL frameworks and reveal that trajectory diversity is fundamentally more important to sample efficiency than the sheer quantity of collected rollouts. Motivated by these insights, we introduce RL Exploration Token (ExToken), a simple yet general framework that condition VLA policies on discrete behavioral priors derived from offline demonstrations for structured exploration. By conditioning the policy on different tokens during rollout collection, ExToken encourages the agent to explore diverse behavioral modes, substantially improving state-action coverage and exploration efficiency. To bridge exploration during training with deterministic inference at deployment, ExToken further incorporates a state-conditioned token selector that adaptively predicts effective behavioral modes for unseen scenarios. Extensive experiments across simulated and real-world robotic manipulation tasks demonstrate that ExToken consistently accelerates convergence, improves task performance, and exhibits strong robustness under highly constrained interaction budgets.

cs.RO

CDCP: Conditional Diffusion Model with Contextual Prompts for Multi-task Offline Safe Reinforcement Learning

Multi-task offline safe reinforcement learning (RL) promises to learn a shared optimal safe policy from offline data across multiple tasks. This paradigm provides an effective means for the widespread application of RL in multi-task scenarios with high risk and interaction costs. However, the triple challenges of multi-tasking, safety constraints, and out-of-distribution (OOD) actions pose a significant hurdle for existing methods to ensure safety while maximizing reward returns. In this work, we propose a Conditional Diffusion model with Contextual Prompts (CDCP) to address these challenges. Concretely, we first rethink the requirements and challenges in current multi-task decision-making and control scenarios and establish the objectives of multi-task offline safe RL. Subsequently, we transform the multi-task constrained optimization problem into a conditional generation problem using the diffusion model. Based on this, we design a classifier-free guided cost-constraint strategy to provide flexible cost constraints and eliminate extrapolation errors from OOD actions via supervised learning. Additionally, we introduce a novel contextual prompting method to enhance multi-task representation accuracy and adaptability to unseen tasks. A gradient loss synchronization strategy is also introduced to eliminate gradient interference, improving training stability. Finally, extensive experiments demonstrate that the CDCP algorithm exhibits higher performance and safety in multi-task scenarios than the current state-of-the-art baseline methods. It meets different cost constraints without further training, providing a more flexible cost-constraint solution for the multi-task safe RL.

cs.LG

Beyond Activation Alignment:The Alignment-Diversity Tradeoff in Task-Aware LLM Quantization

Mixed-precision quantization (MPQ) has become a key technique for deploying large language models under stringent memory and compute constraints. We first identify a phenomenon that we term the Perplexity Illusion: layers ranked as important by perplexity-based sensitivity show little rank correlation with those that are most influential for complex reasoning performance, with Kendall $\tau \approx 0$ in our analysis. We further reveal an Alignment-Diversity Tradeoff: using only target-task calibration data can degrade post-quantization performance, whereas incorporating general-domain data stabilizes sensitivity estimation and improves robustness across tasks. Based on these observations, we propose TASA (Task-Aware Sensitivity Analysis), a two-level framework that jointly optimizes calibration-data composition and mixed-precision bit allocation. Specifically, TASA searches for a calibration-data mixture using a training-free gradient-trace alignment criterion, and then aggregates perplexity and reasoning-oriented sensitivity signals to guide both inter-layer and intra-layer bit allocation. Experiments on LLaMA-3-8B and Qwen2.5-7B reveal a precision inversion: appropriately allocated 3.5-bit models can match or surpass less task-aware 4-bit baselines. At an average precision of 3.5 bits, TASA matches or outperforms several competitive 4-bit uniform baselines in aggregate accuracy, and improves over the strongest W3 baseline on GSM8K by more than 20 absolute points on LLaMA-3-8B. These results show that calibration-data composition substantially affects task-sensitive quantization, a factor underexplored in prior work.

cs.LG

LLM Evolution as an Industry-Scale Ecosystem: A Lifecycle Perspective on Continual Learning

Continual learning capability is critical for Industrial LLMs, as deployed models must be continuously updated to meet evolving requirements and environments, rather than repeatedly retrained from scratch. However, most existing research focuses on improvements on static benchmarks, failing to capture real industrial needs. In this survey, we reformulate Industrial Continual Learning (ICL) for LLMs as a closed-loop update-and-release problem in a versioned ecosystem, where updates propagate hierarchically to industrial, application-specific models and LLM-powered applications, with capability inheritance and transfer across versions and model families. From this ecosystem perspective, we identify three core challenges: repeated adaptation erodes model plasticity, foundation-model upgrades break capability inheritance, and long-term sustainability is constrained by deployment requirements. We then organize the technical landscape of ICL around five lifecycle design principles: preserving plasticity headroom, treating upgrades as capability transfer, enabling trustworthy continual reinforcement learning, making training recipes self-optimizing, and building accountability as a base layer for long-term iteration. For each principle, we synthesize representative technical directions. Finally, we evaluate the maturity of each principle and its technical components via an evidence-based lens, identify key gaps hindering real-world deployment, and outline a practical ICL deployment blueprint and a pathway for feeding industrial realities back into academic research.

cs.LG

iLENS: Interpretable LLM-Guided Mixture-of-Experts for Neuroimaging Survival Analysis

Alzheimer's Disease (AD) is a complex neurodegenerative disorder that continues to impact millions of people worldwide. Predicting AD conversion during the prodromal stage remains critical for disease understanding and patient care. As such, survival models are widely used for AD risk prediction, yet they are typically static predictors with limited interpretability and no capacity for natural language reasoning. In this work, we propose iLENS, an interpretable large language model (LLM) guided framework based on mixture-of-experts (MoE) for survival prediction in AD conversion. Our approach uses LLM to synthesize structured neuroimaging measurements and unstructured information to guide expert routing. Our framework demonstrates competitive predictive performance and capability in patient subtyping. Furthermore, our framework provides transparent, biologically grounded rationales for its routing decisions, bridging the gap between high-performance survival analysis and interpretable clinical decision support.

cs.LG

Expert-Driven Survival Machines: Improving Stratification and Interpretability in Multiple Clinical Cohorts

Survival prediction plays a central role for healthcare providers and clinical researchers. Accurate risk stratification enables early intervention and improved patient management. Most existing deep survival models learn one common feature representation for all patients, which may hide important differences between patient subgroups. In contrast, a Mixture-of-Experts (MoE) framework allows different parts of the model to focus on different patient patterns, leading to more individualized representations. Therefore, in this work, we propose a mixture-of-experts enhanced adaptive deep clustering survival framework (AdaCSM) for modeling such heterogeneous survival patterns. We introduce a routing-based expert mechanism that enables conditional specialization within a parametric survival modeling framework. The proposed architecture allocates patients to specialized risk predictors dynamically while preserving the patient survival and subtype clustering objectives. We compare our method with state-of-the-art survival and deep clustering models on multiple real-world longitudinal clinical cohorts spanning diverse disease domains. The proposed method demonstrates improved predictive performance and leads to interpretable results in survival analysis.

cs.LG

Polar Decoding Tree Pruning Based on Soft Output Extraction

Although the successive cancellation list (SCL) decoding of polar codes exhibits excellent performance, it retains many decoding paths in the list with negligible contribution to the final output, resulting in high sorting and computational complexity. In this letter, we propose a novel pruning strategy to mitigate the decoding complexity. By leveraging the blockwise soft output extraction process of soft-output SCL and soft-output fast SCL decoding, we provide an accurate approximation of the probability that a decoding path is correct, and thus accordingly prune the paths failing to meet a pre-defined reliability threshold. The complexity reduction achieved by the proposed soft-output-based pruned SCL (SOP-SCL) decoder and its fast version, SOP-FSCL decoder, is significant, without any compromise in error-correction performance. Meanwhile, they also prove to be more efficient than state-of-the-art pruned polar decoders.

cs.IT

Khovanov homology: pro-tangles, derived colimits and spectral sequences

This paper introduces \emph{pro-tangles}, a natural generalization of classical tangles, which are functors from the Boolean cube to Bar-Natan's cobordism category. By employing the simplicial Yoneda embedding, we construct the Khovanov simplicial presheaf of a pro-tangle as the total homotopy cofiber over the punctured Boolean cube, and prove that this simplicial presheaf is representable, with representing object the classical Khovanov simplicial object. We establish a fully faithful embedding showing that the weak equivalence class of this simplicial presheaf is determined by the chain homotopy type of the Khovanov complex. Furthermore, we utilize Boolean cube decompositions to construct an algebraic spectral sequence for pro-tangles. This spectral sequence converges to the total Khovanov homology, and its $E_1$ page is explicitly expressed in terms of the Khovanov homology of reduced tangles. This categorical setup yields a functorial interpretation of Reidemeister invariance in terms of morphisms of spectral sequences. By applying the tangle TQFT construction, we study this spectral sequence for Hopf clasps, the fundamental structural building blocks in tangle and link theory. We show that the spectral sequence collapses at the $E_3$ page, which further specializes to an $E_2$-collapse under the restriction to Hopf sums. Finally, we investigate connected sums of pro-tangles and pro-links. To address the module-action dependencies arising from tensor products in multi-connected sums, we introduce a state-dependent modified tensor operator and prove a structural decomposition theorem that generalizes the classical result at the chain complex level.

math.GT

Closed-Form Spectral Regularization for Multi-Task Model Merging

Model merging combines several independently fine-tuned experts into a single multi-task model without any training data, reducing the storage, serving, and decentralized-development costs of large foundation models. State-of-the-art merging methods formulate merging as a layer-wise quadratic interference minimization problem. Although this problem admits an exact closed-form pseudoinverse solution, that solution underperforms hundreds of iterations of gradient descent in practice. The iterative loop dominates the cost of the pipeline, yet its effectiveness has remained unexplained. We revisit this regime and show that the iterative solver does not primarily act as an optimizer; rather, it serves as an implicit spectral regularizer for an ill-posed normal equation, where small-eigenvalue directions of the per-layer interference operator amplify proxy noise. Building on this finding, we formalize multi-task model merging as a noisy linear inverse problem and propose a spectral filtering estimator parameterized by a per-direction filter. We instantiate this estimator with SWUDI, a closed-form method that combines a soft exponential filter, which matches the gradient-flow trajectory of iterative descent, with a hard top-K truncation that suppresses noise-amplifying small-eigenvalue directions. Furthermore, we propose SWUDI-A, an adaptive variant that replaces the global rank hyperparameter with per-layer rank rules, further improving robustness across architectures. Both variants share a single symmetric eigendecomposition per linear layer and require no training data or optimizer state. Across four general benchmarks and a multimodal merging benchmark spanning VQA, Geometry, Chart, OCR, Grounding, and modality merging, our proposed spectral solvers match or outperform state-of-the-art merging methods. Crucially, they reduce wall-clock time by 28-72x and peak GPU memory by up to 50%.

cs.LG

STARS: Spike Tail-Aware Relational Synthesis for ANN-to-SNN Data-Free Knowledge Distillation

SNNs promise energy-efficient and low-latency inference, but their performance still trails that of ANNs. ANN-to-SNN knowledge distillation helps narrow this gap, yet the original training data are often unavailable in practical deployment settings. Existing data-free knowledge distillation (DFKD) methods synthesize surrogate data by matching teacher-side priors, especially BN statistics, but these ANN-oriented constraints mainly regularize mean and variance and therefore remain under-constrained for SNN students whose responses depend on threshold-crossing dynamics. In this paper, we propose Spike Tail-Aware Relational Synthesis (STARS), a plug-and-play method for ANN-to-SNN DFKD that augments standard BN-guided synthesis with two complementary objectives: Relational Consistency Alignment, which preserves cross-sample relational consistency between teacher and student, and Tail-Aware Regularization, which regularizes threshold-relevant tail probabilities through soft exceedance over teacher-derived thresholds. Together, these objectives generate synthetic batches that remain teacher-valid while becoming more informative for SNN students. Experiments on CIFAR-10, CIFAR-100, and Tiny-ImageNet across multiple ANN-SNN pairs show that our method consistently improves conventional DFKD baselines and even surpasses several KD methods, with gains of up to 4.6\% on CIFAR-10 and 6.7\% on CIFAR-100, highlighting the importance of complementing BN matching with relational and tail-aware constraints in SNN-oriented DFKD.

cs.NE

Provable Sparse Inversion and Token Relabel Enhanced One-shot Federated Learning with ViTs

One-Shot Federated Learning, where a central server learns a global model in a single communication round, has emerged as a promising paradigm. However, under extremely non-IID settings, existing data-free methods often generate low-quality data that suffers from severe semantic misalignment with ground-truth labels. To overcome these issues, we propose a novel Federated Model Inversion and Token Relabel (FedMITR) framework, which trains the global model by fully exploiting all patches of synthetic images. Specifically, FedMITR employs sparse model inversion during data generation, selectively inverting semantic foregrounds while halting the inversion of uninformative backgrounds. To address semantically meaningless tokens that hinder ViT predictions, we implement a differentiated strategy: patches with high information density utilize generated pseudo-labels, while patches with low information density are relabeled via ensemble models for robust distillation. Theoretically, our analysis based on algorithmic stability reveals that Sparse Model Inversion eliminates gradient instability arising from background noise, while Token Relabel effectively reduces gradient variance, collectively guaranteeing a tighter generalization bound. Empirically, extensive experimental results demonstrate that FedMITR substantially outperforms existing baselines under various settings.

cs.LG

SimReg: Achieving Higher Performance in the Pretraining via Embedding Similarity Regularization

Pretraining large language models (LLMs) with next-token prediction has led to remarkable advances, yet the context-dependent nature of token embeddings in such models results in high intra-class variance and inter-class similarity, thus hindering the efficiency of representation learning. While similarity-based regularization has demonstrated benefit in supervised fine-tuning and classification tasks, its application and efficacy in large-scale LLM pretraining remains underexplored. In this work, we propose the SimReg, an embedding similarity regularization loss that explicitly encourages token representations with the same ground-truth label within each sequence to be more similar, while enforcing separation from different-label tokens via a contrastive loss. Our analysis reveals that this mechanism introduces gains by enlarging multi-classification margins, thereby enabling more efficient classification. Extensive experiments across dense and Mixture-of-Experts (MoE) architectures demonstrate that SimReg consistently accelerates training convergence by over 30% and improves average zero-shot downstream performance by over 1% across standard benchmarks. Further ablation studies and analyses offer practical insights into hyperparameter tuning and loss effectiveness.

cs.CL